Results 41 to 50 of about 9,178 (213)
Polymersome-Mediated Delivery of Combination Anticancer Therapy to Head and Neck Cancer Cells: 2D and 3D in Vitro Evaluation [PDF]
, 2014 Polymersomes have the potential to encapsulate and deliver chemotherapeutic drugs into tumor cells, reducing off-target toxicity that often compromises anticancer treatment.
Acton S. L. +65 more
core +1 more source
Hallmarks of Polymersome Characterization. [PDF]
ACS Mater AuPolymersomes have the potential to become the next generation of vesicular drug delivery systems. Their high chemical versatility and in certain cases higher membrane stability than liposomes raised the high hopes for polymersomes as a drug carrier, but the clinical translation has been slow.
Matoori S.
europepmc +4 more sources
Nanoporous silica-based protocells at multiple scales for designs of life and nanomedicine. [PDF]
, 2015 Various protocell models have been constructed de novo with the bottom-up approach. Here we describe a silica-based protocell composed of a nanoporous amorphous silica core encapsulated within a lipid bilayer built by self-assembly that provides for ...
Brinker, C Jeffrey +3 more
core +2 more sources
Bioengineering & Translational Medicine, 2023 Membrane proteins (MPs) play key roles in cellular signaling pathways and are responsible for intercellular and intracellular interactions. Dysfunctional MPs are directly related to the pathogenesis of various diseases, and they have been exploited as ...
Chih Hung Lo, Jialiu Zeng
doaj +1 more source
Frontiers in Chemical Engineering, 2022 GM1 gangliosidosis is a lysosomal storage disorder caused by deficiency of β-galactosidase (βgal) and subsequent accumulation of GM1 ganglioside in lysosomes. One of the pathological aspects of GM1 gangliosidosis, and other storage disorders, is impaired
Bipin Chakravarthy Paruchuri +3 more
doaj +1 more source
Smart systems related to polypeptide sequences [PDF]
, 2016 Increasing interest for the application of polypeptide-based smart systems in the biomedical field has developed due to the advantages given by the peptidic sequence.
Franco García, María Lourdes +2 more
core +2 more sources
Cascade Reactions in Multicompartmentalized Polymersomes [PDF]
Angewandte Chemie, 2013 AbstractEnzyme‐filled polystyrene‐b‐poly(3‐(isocyano‐L‐alanyl‐aminoethyl)thiophene) (PS‐b‐PIAT) nanoreactors are encapsulated together with free enzymes and substrates in a larger polybutadiene‐b‐poly(ethylene oxide) (PB‐b‐PEO) polymersome, forming a multicompartmentalized structure, which shows structural resemblance to the cell and its organelles. An
Peters, R.J.R.W. +6 more
openaire +4 more sources
Fluid Vesicles with Viscous Membranes in Shear Flow [PDF]
, 2004 The effect of membrane viscosity on the dynamics of vesicles in shear flow is studied. We present a new simulation technique, which combines three-dimensional multi-particle collision dynamics for the solvent with a dynamically-triangulated membrane ...
Gompper, Gerhard, Noguchi, Hiroshi
core +2 more sources
Polymerization-Induced Polymersome Fusion [PDF]
Journal of the American Chemical Society, 2019 The dynamic interactions of membranes, particularly their fusion and fission, are critical for the transmission of chemical information between cells. Fusion is primarily driven by membrane tension built up through membrane deformation. For artificial polymersomes, fusion is commonly induced via the external application of a force field. Herein, fusion-
Spyridon Varlas +5 more
openaire +3 more sources
Angewandte Chemie, EarlyView.Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo +3 more
wiley +2 more sources