Results 51 to 60 of about 3,285 (181)

Ionic Combisomes: A New Class of Biomimetic Vesicles to Fuse with Life

open access: yesAdvanced Science, 2022
The construction of biomembranes that faithfully capture the properties and dynamic functions of cell membranes remains a challenge in the development of synthetic cells and their application.
Anna M. Wagner   +13 more
doaj   +1 more source

Crystalline Poly(L‐Lactic Acid) Nanoparticles via Nonsolvent‐Induced Cascade Phase Separation

open access: yesJournal of Polymer Science, EarlyView.
Water is used as the nonsolvent to induce liquid/liquid phase separation (LLPS) of poly(L‐lactic acid) (PLLA)/propylene carbonate solution and PLLA crystallization. Due to the two levels of cascade LLPS coupled with confined PLLA crystallization, three types of polymeric nanoparticles, including PLLA single crystals, Ouzo crystalsomes, and sheaf‐like ...
Niloofar Esmati   +3 more
wiley   +1 more source

Elucidating the Influence of Tumor Presence on the Polymersome Circulation Time in Mice

open access: yesPharmaceutics, 2019
The use of nanoparticles as tumor-targeting agents is steadily increasing, and the influence of nanoparticle characteristics such as size and stealthiness have been established for a large number of nanocarrier systems.
Robin M. de Kruijff   +7 more
doaj   +1 more source

Polymersome‐Enabled Multimodal Delivery of Tobramycin and Doripenem for Targeted Eradication of Pseudomonas aeruginosa Biofilms in Chronic Rhinosinusitis

open access: yesSmall, EarlyView.
Schematic representation of diffusion‐based versus pH‐triggered drug release within a bacterial biofilm. In diffusion‐based systems, drug cargo is gradually released independent of local pH, resulting in rapid burst release and reduced sustained concentrations.
Amalie Kjær Andresen   +9 more
wiley   +1 more source

Environmental Impact of Synthetic Cell Technology: Review of Life Cycle Assessment Data for Feedstocks and Production Methods

open access: yesChemBioChem, Volume 27, Issue 15, 14 August 2026.
Synthetic cells are positioned as enablers of green technology. But what is known about the environmental impact of synthetic cell production? In this review, we examine drivers of greenhouse gas emissions, toxicity, and other environmental impact categories of synthetic cell components.
Christina Hopf   +2 more
wiley   +1 more source

The Therapeutic Potential of H2S‐Releasing Platforms in Cardiovascular Applications

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 8, August 2026.
The Therapeutic Potential of H2S‐Releasing Platforms. ABSTRACT Once known as a toxic gas, hydrogen sulfide (H2S) is now making its way into many therapeutic applications. Similar to its other fellow endogenous gasotransmitters, nitric oxide and carbon monoxide, H2S is a small gas with a short half‐life, making it extremely capable of penetrating ...
Tia N. Shorter, Elizabeth J. Brisbois
wiley   +1 more source

Stimuli-responsive polymersomes and nanoreactors [PDF]

open access: yesJournal of Materials Chemistry B, 2016
Macromolecular self-assembly is attracting increasing scientific interest in polymer science.
Che, H.   +2 more
openaire   +3 more sources

Photoactivated Signaling Networks using DNA‐Based Synthetic Organelles as Biomimetic Protocells

open access: yesAngewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Light‐triggered intercommunication between two types of organelle‐loaded liposomes lead to DNAzyme‐mediated on transcription‐guided structural reconfiguration of the organelles. ABSTRACT Membraneless organelles formed by phase‐separated nucleic acid or protein condensates play vital roles in regulating cellular functions.
Huiying Xue   +6 more
wiley   +2 more sources

Redox-sensitive iodinated polymersomes carrying histone deacetylase inhibitor as a dual-functional nano-radiosensitizer for enhanced radiotherapy of breast cancer

open access: yesDrug Delivery, 2021
Radiotherapy (RT) is a frequently used means in clinical tumor treatment. The outcome of RT varies, however, to a great extent, due to RT resistance or intolerable dose, which might be resolved by the development of radio-sensitizing strategies. Here, we
Zhehong Zhu   +9 more
doaj   +1 more source

Preparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation

open access: yesPharmaceuticals, 2023
Dual centrifugation (DC) is an innovative in-vial homogenization and in-vial nanomilling technique that has been in use for the preparation of liposomes for more than one decade.
Jonas K. Koehler   +4 more
doaj   +1 more source

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