Results 71 to 80 of about 3,285 (181)
Artificial cell: An emerging bioactive material with advanced applications in cancer theranostics
Artificial cells are emerging as attractive biomimetic bioactive materials that recapitulate key structures and functions of natural cells. This review systematically summarizes their major types, versatile fabrication strategies, tuneable properties and programmable biomimetic behaviours, highlights their cutting‐edge integrated applications in cancer
Daikun Wu, Shuo Yang, Hongjing Dou
wiley +1 more source
Polymersomes with micellar patches
Hollow block copolymer particles called polymer vesicles (polymersomes) serve as versatile containers for compartmentalization in synthetic biology and drug delivery. Recently, there has been growing interest in using polymersomes as colloidal building blocks for creating higher-order clustered structures.
Chin Ken Wong +2 more
openaire +2 more sources
A micro-incubator for cell and tissue imaging
A low-cost micro-incubator for imaging dynamic processes in living cells and tissues has been developed. This micro-incubator provides a tunable environment that can be altered to study responses of cell monolayers for several days as well as relatively ...
Cyril Picard +6 more
doaj +1 more source
Polymersome Crack Film and Its Templating Function in Silica and Gold Deposition
Polymersome dispersion self‐assembled from PEI‐b‐PPOZ block copolymer in aqueous media can be drop‐cast onto substrates to give cracked films. The cracked film served as an effective catalytic template for the hydrolytic polycondensation of TMOS, producing silica‐coated films that retained the original crack pattern. In addition, gold deposition on the
Yuya Saza +5 more
wiley +1 more source
Enzymatically triggered rupture of polymersomes [PDF]
Polymersomes are robust vesicles made from di-block co-polymers. We have engineered a two step enzymatic cascade to trigger the release of contents from polymersomes, in which extravesicular glucose oxidase makes hydrogen peroxide, when then penetrates the membrane and is converted by entrapped catalase to oxygen, leading to vesicle failure.
Woo-Sik, Jang +6 more
openaire +2 more sources
Poly(dimethylsiloxane-ethylene oxide) (PDMS-PEO) and poly(butadiene-b-ethylene oxide) (PBd-PEO) are two block copolymers which separately form vesicles with disparate membrane permeabilities and fluidities. Thus, hybrid vesicles formed from both PDMS-PEO
Jeffery Gaspard +5 more
doaj +1 more source
Advances in Polyethyleneimine‐Derived Nanoformulations
This article illustrates the cytotoxic effects of polyethyleneimine (PEI) on cell membranes and mitochondria, the strategies employed to mitigate PEI‐associated toxicity through chemical modification, PEGylation, and structural optimization, and the major types of PEI‐based formulations developed for the delivery of therapeutic drugs, nucleic acids ...
Mohamed S. Attia +2 more
wiley +1 more source
Current Perspectives on STING Agonists for Anticancer Drug Development
The molecular structures of STING agonists play a decisive role in regulating the STING pathway. Their distinct scaffolds and functional groups orchestrate receptor binding, conformational activation, and the subsequent immune response. ABSTRACT The cyclic GMP‐AMP (cGAS) synthase and stimulator of interferon genes signaling pathway plays a central role
Dilay Kahvecioglu Cicek
wiley +1 more source
POLIMEROSSOMOS VERSUS LIPOSSOMOS: A EVOLUÇÃO DA “BALA MÁGICA”
Polymeric vesicles known as polymersomes are formed by the self-assemble of amphiphilic block copolymers and have structural organization similar to liposomes.
Alexsandra Conceição Apolinário +3 more
doaj +1 more source
Targeted delivery of Tet1 peptide functionalized polymersomes to the rat cochlear nerve
Ya Zhang1, Weikai Zhang1*, Alexander H Johnston2*, Tracey A Newman3, Ilmari Pyykkö1, Jing Zou1 1Department of Otolaryngology, University of Tampere, Medical School, Tampere, Finland; 2Centre for Biological Sciences, 3Clinical Neurosciences ...
Zhang Y +5 more
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