Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]
open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura +6 more
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A facile method for anti-cancer drug encapsulation into polymersomes with a core-satellite structure
Polymersomes possess the self-assembly vesicular structure similar to liposomes. Although a variety of comparisons between polymersomes and liposomes in the aspects of physical properties, preparation and applications have been elaborated in many studies,
Hongchao Xu +10 more
doaj +1 more source
Preparation and characterization of PCL-PEG-PCL polymersomes for delivery of clavulanic acid
The Clavulanic acid (CLV) is a suicide inhibitor of bacterial beta-lactamase enzymes from Streptomyces clavuligerus. In the present study, a reliable drug delivery system using poly (ε-caprolactone)-poly (ethylene glycol)-poly (ε-caprolactone) (PCL-PEG ...
Hossein Danafar
doaj +1 more source
Tuning the Elasticity of Polymersomes for Brain Tumor Targeting
Nanoformulations show great potential for delivering drugs to treat brain tumors. However, how the mechanical properties of nanoformulations affect their ultimate brain destination is still unknown.
Meng Zheng +10 more
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Redox-Responsive Polymersomes as Smart Doxorubicin Delivery Systems
Stimuli-responsive polymersomes have emerged as smart drug delivery systems for programmed release of highly cytotoxic anticancer agents such as doxorubicin hydrochloride (Dox·HCl).
Carmen Ferrero +2 more
doaj +1 more source
A new approach to high resolution, high contrast electron microscopy of macromolecular block copolymer assemblies [PDF]
Determining the structure of macromolecular samples is vital for understanding and adapting their function. Transmission electron microscopy (TEM) is widely used to achieve this, but, owing to the weak electron scattering cross-section of carbon, TEM ...
Allen +36 more
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Construction of membrane-bound artificial cells using microfluidics: a new frontier in bottom-up synthetic biology [PDF]
The quest to construct artificial cells from the bottom-up using simple building blocks has received much attention over recent decades and is one of the grand challenges in synthetic biology.
Elani, Y
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Photoactivated Polymersome Nanomotors: Traversing Biological Barriers [PDF]
AbstractSynthetic nanomotors are appealing delivery vehicles for the dynamic transport of functional cargo. Their translation toward biological applications is limited owing to the use of non‐degradable components. Furthermore, size has been an impediment owing to the importance of achieving nanoscale (ca.
Jingxin Shao +4 more
openaire +5 more sources
Photopolymerization-Induced Polymersome Rupture [PDF]
Poly(butadiene)- b-poly(ethylene oxide) (PBut2.5- b-PEO1.3) giant polymersomes were prepared using an emulsion-centrifugation method. The impact of a fast decrease of the osmotic pressure inside the lumen of giant PBut- b-PEO vesicles was studied by confocal microscopy. This osmotic imbalance was created by performing the photoinduced polymerization of
Sophie C. Larnaudie +4 more
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Asymmetrical Polymer Vesicles for Drug delivery and Other Applications
Scientists have been attracted by polymersomes as versatile drug delivery systems since the last two decades. Polymersomes have the potential to be versatile drug delivery systems because of their tunable membrane formulations, stabilities in vivo ...
Yi Zhao +6 more
doaj +1 more source

