Results 31 to 40 of about 3,285 (181)
Engineering Polymersome Protocells [PDF]
The Journal of Physical Chemistry Letters, 2011 The field of biomimicry is embracing the construction of complex assemblies that imitate both biological structure and function. Advancements in the design of these mimetics have generated a growing vision for creating an artificial or proto- cell. Polymersomes are vesicles that can be made from synthetic, biological or hybrid polymers and can be used ...
Neha P, Kamat +2 more
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Hallmarks of Polymersome Characterization. [PDF]
ACS Mater AuPolymersomes have the potential to become the next generation of vesicular drug delivery systems. Their high chemical versatility and in certain cases higher membrane stability than liposomes raised the high hopes for polymersomes as a drug carrier, but the clinical translation has been slow.
Matoori S.
europepmc +4 more sources
Bio-Inspired Polymersome Nanoreactors [PDF]
CHIMIA, 2019 Abstract: Two key concepts in living organisms are that biochemical reactions are sequestered into reaction compartments such as cells and organelles, and that many of the complex biological reaction cascades involve transient activation of reactions in response to external triggers. Here we review our efforts to implement these concepts into
Rifaie-Graham, Omar +2 more
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Asymmetrical Polymer Vesicles for Drug delivery and Other Applications
Frontiers in Pharmacology, 2017 Scientists have been attracted by polymersomes as versatile drug delivery systems since the last two decades. Polymersomes have the potential to be versatile drug delivery systems because of their tunable membrane formulations, stabilities in vivo ...
Yi Zhao +6 more
doaj +1 more source
Cascade Reactions in Multicompartmentalized Polymersomes [PDF]
Angewandte Chemie, 2013 AbstractEnzyme‐filled polystyrene‐b‐poly(3‐(isocyano‐L‐alanyl‐aminoethyl)thiophene) (PS‐b‐PIAT) nanoreactors are encapsulated together with free enzymes and substrates in a larger polybutadiene‐b‐poly(ethylene oxide) (PB‐b‐PEO) polymersome, forming a multicompartmentalized structure, which shows structural resemblance to the cell and its organelles. An
Peters, R.J.R.W. +6 more
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Design of chimaeric polymersomes
Faraday Discussions, 2005 We discuss the development of hierarchical polymer particles, or variegated polymersome composites, in which at least two different components are phase separated within one polymersome chimaera. We briefly discuss the present status in experimental polymersome research, and then discuss a speculative design strategy, based on mesoscopic simulations ...
J. G. E. M. Fraaije +4 more
openaire +3 more sources
Bioengineering & Translational Medicine, 2023 Membrane proteins (MPs) play key roles in cellular signaling pathways and are responsible for intercellular and intracellular interactions. Dysfunctional MPs are directly related to the pathogenesis of various diseases, and they have been exploited as ...
Chih Hung Lo, Jialiu Zeng
doaj +1 more source
Frontiers in Chemical Engineering, 2022 GM1 gangliosidosis is a lysosomal storage disorder caused by deficiency of β-galactosidase (βgal) and subsequent accumulation of GM1 ganglioside in lysosomes. One of the pathological aspects of GM1 gangliosidosis, and other storage disorders, is impaired
Bipin Chakravarthy Paruchuri +3 more
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Pharmaceutics, 2023 The development of new approaches for the treatment of the increasingly antibiotic-resistant pathogen Pseudomonas aeruginosa was targeted by enhancing the effect of local antimicrobial photodynamic therapy (aPDT) using poly(ethylene glycol)-block-poly ...
Kawaljit Kaur +3 more
doaj +1 more source
Advanced Science, 2019 Understanding the diffusion of nanoparticles through permeable membranes in cell mimics paves the way for the construction of more sophisticated synthetic protocells with control over the exchange of nanoparticles or biomacromolecules between different ...
Hannes Gumz +7 more
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