Results 11 to 20 of about 9,178 (213)

Morphogenesis of starfish polymersomes

Nature Communications, 2023
The enhanced membrane stability and chemical versatility of polymeric vesicles have made them promising tools in micro/nanoreactors, drug delivery, cell mimicking, etc. However, shape control over polymersomes remains a challenge and has restricted their
Jiawei Sun, Sandra Kleuskens, Jiabin Luan, Danni Wang, Shaohua Zhang, Wei Li, Gizem Uysal, Daniela A. Wilson   +7 more
doaj   +5 more sources

Click Chemistry in Polymersome Technology

Pharmaceuticals
Polymersomes, self-assembled nanoparticles composed of amphiphilic block copolymers, have emerged as promising versatile nanovesicles with various applications, such as drug delivery, medical imaging, and diagnostics.
Nuno M. Saraiva, Ana Alves, Paulo C. Costa, Marta Correia-da-Silva   +3 more
doaj   +3 more sources

Hydrogels Incorporating Donor-Acceptor Stenhouse Adducts as a Platform for Photoinduced, On-Off Switchable Release of Small Molecule Cargos. [PDF]

Macromol Rapid Commun
Donor–acceptor Stenhouse aDdducts (DASAs) are known for their photoinduced tautomerization, which, when conjugated to block copolymers, can self‐assemble into tuneable polymersomes. These DASA‐polymersomes are being investigated for light‐controlled cargo release in biomedical applications.
Dell TN, Cammack-Najera A, Tresa R, Matubbar F, Kaya B, Lathan U, Chami M, DiNardi RG, Rifaie-Graham O, Wojciechowski JP, Stevens MM.   +10 more
europepmc   +2 more sources

Triggered Polymersome Fusion

Journal of the American Chemical Society, 2023
The contents of biological cells are retained within compartments formed of phospholipid membranes. The movement of material within and between cells is often mediated by the fusion of phospholipid membranes, which allows mixing of contents or excretion of material into the surrounding environment.
Stephen D. P. Fielden, Matthew J. Derry, Alisha J. Miller, Paul D. Topham, Rachel K. O’Reilly   +4 more
openaire   +2 more sources

Leuko-polymersomes [PDF]

Faraday Discussions, 2008
Polymersomes are vesicles whose membranes are comprised of self-assembled amphiphilic block co-polymers. Synthetic control of block co-polymer chemistry provides an advantageous diversity of polymersome functions, ranging from tunable materials strength, superior encaspulation of hydrophobic and hydrophilic drugs and optical dyes, and facile ...
Daniel A, Hammer, Gregory P, Robbins, Jered B, Haun, John J, Lin, Wei, Qi, Lee A, Smith, P Peter, Ghoroghchian, Michael J, Therien, Frank S, Bates   +8 more
openaire   +2 more sources

Polymersomes Eradicating Intracellular Bacteria [PDF]

ACS Nano, 2020
Mononuclear phagocytes such as monocytes, tissue-specific macrophages, and dendritic cells are primary actors in both innate and adaptive immunity. These professional phagocytes can be parasitized by intracellular bacteria, turning them from housekeepers to hiding places and favoring chronic and/or disseminated infection.
Fenaroli F., Robertson J. D., Scarpa E., Gouveia V. M., Di Guglielmo C., De Pace C., Elks P. M., Poma A., Evangelopoulos D., Canseco J. O., Prajsnar T. K., Marriott H. M., Dockrell D. H., Foster S. J., McHugh T. D., Renshaw S. A., Marti J. S., Battaglia G., Rizzello L.   +18 more
openaire   +6 more sources

Fabrication of Polymersomes: A Macromolecular Architecture in Nanotherapeutics

Chemistry, 2022
In consideration of the issues of drug delivery systems, the artificial vesicle structures composed of block copolymers called polymersomes recently gained considerable attention.
Pragya Pallavi, Karthick Harini, Pemula Gowtham, Koyeli Girigoswami, Agnishwar Girigoswami   +4 more
doaj   +1 more source

The Role of Membrane Fluidization in the Gel-Assisted Formation of Giant Polymersomes. [PDF]

PLoS ONE, 2016
Polymersomes are being widely explored as synthetic analogs of lipid vesicles based on their enhanced stability and potential uses in a wide variety of applications in (e.g., drug delivery, cell analogs, etc.).
Adrienne C Greene, Ian M Henderson, Andrew Gomez, Walter F Paxton, Virginia VanDelinder, George D Bachand   +5 more
doaj   +1 more source

Challenges in estimating the encapsulation efficiency of proteins in polymersomes - Which is the best method?

Brazilian Journal of Pharmaceutical Sciences, 2023
Polymersomes are nanometric vesicles that can encapsulate large and hydrophilic biomolecules, such as proteins, in the aqueous core. Data in literature show large variation in encapsulation efficiency (%EE) values depending on the method used for ...
Jorge Javier Muso-Cachumba, Grace Ruiz-Lara, Gisele Monteiro, Carlota de Oliveira Rangel-Yagui   +3 more
doaj   +1 more source

Bio-Inspired Amphiphilic Block-Copolymers Based on Synthetic Glycopolymer and Poly(Amino Acid) as Potential Drug Delivery Systems [PDF]

, 2020
In this work, a method to prepare hybrid amphiphilic block copolymers consisting of biocompatible synthetic glycopolymer with non-degradable backbone and biodegradable poly(amino acid) (PAA) was developed.
Dobrodumov, Anatoliy, Kashina, Anna, Korzhikova-Vlakh, Evgenia, Lavrentieva, Antonina, Levit, Mariia, Rühl, Eckart, Scheper, Thomas, Tennikova, Tatiana, Vdovchenko, Alena, Zakharova, Natalya, Zashikhina, Natalia   +10 more
core   +1 more source