Results 11 to 20 of about 3,285 (181)
Morphogenesis of starfish polymersomes
Nature Communications, 2023 The enhanced membrane stability and chemical versatility of polymeric vesicles have made them promising tools in micro/nanoreactors, drug delivery, cell mimicking, etc. However, shape control over polymersomes remains a challenge and has restricted their
Jiawei Sun +7 more
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Click Chemistry in Polymersome Technology
PharmaceuticalsPolymersomes, self-assembled nanoparticles composed of amphiphilic block copolymers, have emerged as promising versatile nanovesicles with various applications, such as drug delivery, medical imaging, and diagnostics.
Nuno M. Saraiva +3 more
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Faraday Discussions, 2008 Polymersomes are vesicles whose membranes are comprised of self-assembled amphiphilic block co-polymers. Synthetic control of block co-polymer chemistry provides an advantageous diversity of polymersome functions, ranging from tunable materials strength, superior encaspulation of hydrophobic and hydrophilic drugs and optical dyes, and facile ...
Daniel A, Hammer +8 more
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Fabrication of Polymersomes: A Macromolecular Architecture in Nanotherapeutics
Chemistry, 2022 In consideration of the issues of drug delivery systems, the artificial vesicle structures composed of block copolymers called polymersomes recently gained considerable attention.
Pragya Pallavi +4 more
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The Role of Membrane Fluidization in the Gel-Assisted Formation of Giant Polymersomes. [PDF]
PLoS ONE, 2016 Polymersomes are being widely explored as synthetic analogs of lipid vesicles based on their enhanced stability and potential uses in a wide variety of applications in (e.g., drug delivery, cell analogs, etc.).
Adrienne C Greene +5 more
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Polymersomes in “Gelly” Polymersomes: Toward Structural Cell Mimicry [PDF]
Langmuir, 2011 We demonstrate here the formation of compartmentalized polymersomes with an internal "gelly" cavity using an original and versatile process. Nanosize polymersomes of poly(trimethylene carbonate)-b-poly(L-glutamic acid) (PTMC-b-PGA), formed by a solvent displacement method are encapsulated with a rough "cytoplasm mimic" in giant polymersomes of poly ...
Marguet, Maïté +2 more
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Brazilian Journal of Pharmaceutical Sciences, 2023 Polymersomes are nanometric vesicles that can encapsulate large and hydrophilic biomolecules, such as proteins, in the aqueous core. Data in literature show large variation in encapsulation efficiency (%EE) values depending on the method used for ...
Jorge Javier Muso-Cachumba +3 more
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A mathematical investigation into the uptake kinetics of nanoparticles in vitro.
PLoS ONE, 2021 Nanoparticles have the potential to increase the efficacy of anticancer drugs whilst reducing off-target side effects. However, there remain uncertainties regarding the cellular uptake kinetics of nanoparticles which could have implications for ...
Hannah West +8 more
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The Impact of MiR-33a-5p Inhibition in Pro-Inflammatory Endothelial Cells
Diseases, 2023 Evidence suggests cholesterol accumulation in pro-inflammatory endothelial cells (EC) contributes to triggering atherogenesis and driving atherosclerosis progression.
Kun Huang +8 more
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Photo-Responsive Polymersomes as Drug Delivery System for Potential Medical Applications
Molecules, 2020 Due to a strong retardation effect of o-nitrobenzyl ester on polymerization, it is still a great challenge to prepare amphiphilic block copolymers for polymersomes with a o-nitrobenzyl ester-based hydrophobic block.
Wanting Hou +5 more
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