Results 21 to 30 of about 9,178 (213)
Adaptive Polymersome Nanoreactors [PDF]
ChemNanoMat, 2019 AbstractAdaptive polymersome systems have gained much interest in a wide variety of research fields, ranging from cell mimics to nanomedicine, because of their high stability, tunable shape and size. Furthermore, polymersomes can be effectively transformed into nanoreactors via the incorporation of catalytic species. By employing polymersomes which are
Che, Hailong, van Hest, Jan C. M.
openaire +1 more source
Polymersomes in “Gelly” Polymersomes: Toward Structural Cell Mimicry [PDF]
Langmuir, 2011 We demonstrate here the formation of compartmentalized polymersomes with an internal "gelly" cavity using an original and versatile process. Nanosize polymersomes of poly(trimethylene carbonate)-b-poly(L-glutamic acid) (PTMC-b-PGA), formed by a solvent displacement method are encapsulated with a rough "cytoplasm mimic" in giant polymersomes of poly ...
Maïté, Marguet +2 more
openaire +2 more sources
A mathematical investigation into the uptake kinetics of nanoparticles in vitro.
PLoS ONE, 2021 Nanoparticles have the potential to increase the efficacy of anticancer drugs whilst reducing off-target side effects. However, there remain uncertainties regarding the cellular uptake kinetics of nanoparticles which could have implications for ...
Hannah West +8 more
doaj +1 more source
Paramagnetic Porous Polymersomes [PDF]
Langmuir, 2008 The ability of chelated Gd to serve as an effective magnetic resonance (MR) contrast agent largely depends on fast exchange rates between the Gd-bound water molecules and the surrounding bulk water. Because water diffuses slowly across lipid bilayers, liposomes with encapsulated chelated Gd have not been widely adopted as MR contrast agents.
Cheng, Zhiliang, Tsourkas, Andrew
openaire +2 more sources
The Impact of MiR-33a-5p Inhibition in Pro-Inflammatory Endothelial Cells
Diseases, 2023 Evidence suggests cholesterol accumulation in pro-inflammatory endothelial cells (EC) contributes to triggering atherogenesis and driving atherosclerosis progression.
Kun Huang +8 more
doaj +1 more source
Engineering Polymersome Protocells [PDF]
The Journal of Physical Chemistry Letters, 2011 The field of biomimicry is embracing the construction of complex assemblies that imitate both biological structure and function. Advancements in the design of these mimetics have generated a growing vision for creating an artificial or proto- cell. Polymersomes are vesicles that can be made from synthetic, biological or hybrid polymers and can be used ...
Neha P, Kamat +2 more
openaire +2 more sources
Photo-Responsive Polymersomes as Drug Delivery System for Potential Medical Applications
Molecules, 2020 Due to a strong retardation effect of o-nitrobenzyl ester on polymerization, it is still a great challenge to prepare amphiphilic block copolymers for polymersomes with a o-nitrobenzyl ester-based hydrophobic block.
Wanting Hou +5 more
doaj +1 more source
Bio-Inspired Polymersome Nanoreactors [PDF]
CHIMIA, 2019 Abstract: Two key concepts in living organisms are that biochemical reactions are sequestered into reaction compartments such as cells and organelles, and that many of the complex biological reaction cascades involve transient activation of reactions in response to external triggers. Here we review our efforts to implement these concepts into
Rifaie-Graham, Omar +2 more
openaire +5 more sources
A novel diblock copolymer of (monomethoxy poly [ethylene glycol]-oleate) with a small hydrophobic fraction to make stable micelles/polymersomes for curcumin delivery to cancer cells [PDF]
, 2014 Curcumin is a potent natural anticancer agent, but its effectiveness is limited by properties such as very low solubility, high rate of degradation, and low rate of absorption of its hydrophobic molecules in vivo.
Erfani-Moghadam, V. +5 more
core +2 more sources
Chemical Communications, 2007 Polymersomes, composed of amphiphilic polystyrene-block-poly(acrylic acid) (PS-b-PAA), with the periphery being covered with azide groups, were used for further functionalization using "click" chemistry.
Opsteen, J.A. +4 more
openaire +3 more sources