Results 51 to 60 of about 2,445 (197)
Frontiers in Chemical Engineering, 2022 GM1 gangliosidosis is a lysosomal storage disorder caused by deficiency of β-galactosidase (βgal) and subsequent accumulation of GM1 ganglioside in lysosomes. One of the pathological aspects of GM1 gangliosidosis, and other storage disorders, is impaired
Bipin Chakravarthy Paruchuri +3 more
doaj +1 more source
The Role of Membrane Fluidization in the Gel-Assisted Formation of Giant Polymersomes. [PDF]
PLoS ONE, 2016 Polymersomes are being widely explored as synthetic analogs of lipid vesicles based on their enhanced stability and potential uses in a wide variety of applications in (e.g., drug delivery, cell analogs, etc.).
Adrienne C Greene +5 more
doaj +1 more source
Probing and Tuning the Permeability of Polymersomes [PDF]
ACS Central Science, 2020 Abstract Polymersomes are a class of synthetic vesicles composed of a polymer membrane surrounding an aqueous inner cavity. In addition to their overall size, the thickness and composition of polymersome membranes determine the range of potential applications in which they can be employed.
Alisha J. Miller +3 more
openaire +3 more sources
Polymersome Shape Transformation at the Nanoscale [PDF]
ACS Nano, 2013 Polymer vesicles, also named polymersomes, are valuable candidates for drug delivery and micro- or nanoreactor applications. As far as drug delivery is concerned, the shape of the carrier is believed to have a strong influence on the biodistribution and cell internalization.
Salva, Romain +6 more
openaire +3 more sources
Polymersome Nanoreactors for Enzymatic Ring-Opening Polymerization
, 2016 Polystyrene-polyisocyanopeptide (PS-PIAT) polymersomes containing CALB in two different locations, one in the aqueous inner compartment and one in the bilayer, were investigated for enzymatic ring-opening polymerization of lactones in water.
Jeroen J. L. M. Cornelissen (1530451) +5 more
core +1 more source
International Journal of Nanomedicine, 2021 Duan X, Lu L, Wang Y, et al. Int J Nanomedicine. 2017;12:6705–6719. The authors have advised that Figures 6, 8 and 9 on pages 6713, 6715 and 6716, respectively, of the published paper are incorrect. The errors were introduced by the Editorial staff
Duan X +9 more
doaj
, 2021 Diabetic wounds are difficult to heal due to recurrent bacterial infection, decreased proliferation, and migration of epidermal and endothelial cells. This is related to impaired leukocyte function and low blood concentrations of H2S in diabetic patients.
Jianzhong Du +21 more
core +1 more source
ChemPhysMater, 2022 Temozolomide (TMZ) is a clinically approved drug for glioblastoma (GBM) therapy. However, as a result of methylguanine-DNA-methyltransferase (MGMT), which is able to repair damaged DNA-damage repairing, TMZ usually yields unsatisfactory therapeutic ...
Meng Zheng +10 more
doaj +1 more source
Modular Approach to the Functionalization of Polymersomes [PDF]
Biomacromolecules, 2020 Abstract Functionalizing polymersomes remains a challenge due to the limitation in reaction conditions applicable to the chemistry on the surface, hindering their application for selective targeting. In order to overcome this limitation, functionalization can be introduced right before the self-assembly.
Sjoerd J. Rijpkema +5 more
openaire +3 more sources
DNA-based assembly of multi-compartment polymersome networks
, 2020 Polymersomes exhibit increased stability and reduced permeability compared to conventional lipid‐based compartments—making them an increasingly popular choice for the bottom‐up construction of synthetic cells.
Rongcong Luo +7 more
core +1 more source