Results 31 to 40 of about 2,445 (197)

Polymersome-Encapsulated Chemosensors: New Design Strategies toward Biofluid-Applicable Cucurbit[7]uril Indicator Displacement Assays [PDF]

The development of supramolecular cucurbit[7]uril-based chemosensors for the detection of bioanalytes in biofluids such as untreated human serum and inside cells is a challenging task due to competition with proteins and inorganic salts.
Rachel K. O’Reilly (1293360), Sam J. Parkinson (17404391), Pierre Picchetti (8148897), Laura M. Grimm (11920232), Amanda K. Pearce (1514062), Frank Biedermann (1303992)   +5 more
core   +4 more sources

Intravitreal Polymeric Nanocarriers with Long Ocular Retention and Targeted Delivery to the Retina and Optic Nerve Head Region

Pharmaceutics, 2021
Posterior eye tissues, such as retina, are affected in many serious eye diseases, but drug delivery to these targets is challenging due to various anatomical eye barriers.
Vijayabhaskarreddy Junnuthula, Amir Sadeghi Boroujeni, Shoupeng Cao, Shirin Tavakoli, Roxane Ridolfo, Elisa Toropainen, Marika Ruponen, Jan C. M. van Hest, Arto Urtti   +8 more
doaj   +1 more source

“Clickable” polymersomes

Chemical Communications, 2007
Polymersomes, composed of amphiphilic polystyrene-block-poly(acrylic acid) (PS-b-PAA), with the periphery being covered with azide groups, were used for further functionalization using "click" chemistry.
Opsteen, J.A., Brinkhuis, R.P., Teeuwen, R.L.M., Lowik, D.W.P.M., Hest, J.C.M. van   +4 more
openaire   +3 more sources

Electromechanical Limits of Polymersomes [PDF]

Physical Review Letters, 2001
Physical Review ...
Aranda-Espinoza, Helim, Bermudez, Harry, Bates, Frank S, Discher, Dennis E   +3 more
openaire   +4 more sources

Polymersome-encapsulated chemosensors: New design strategies toward biofluid-pplicable cucurbit[7]uril indicator displacement assays

The development of supramolecular cucurbit[7]uril-based chemosensors for the detection of bioanalytes in biofluids such as untreated human serum and inside cells is a challenging task due to competition with proteins and inorganic salts.
Laura M. Grimm (20878666), Rachel K. O'Reilly (2472382), Sam J. Parkinson (17404391), Amanda Pearce (13768648), Pierre Picchetti (8148897), Frank Biedermann (1303992)   +5 more
core   +5 more sources

Toward Functional Synthetic Cells: In‐Depth Study of Nanoparticle and Enzyme Diffusion through a Cross‐Linked Polymersome Membrane

Advanced Science, 2019
Understanding the diffusion of nanoparticles through permeable membranes in cell mimics paves the way for the construction of more sophisticated synthetic protocells with control over the exchange of nanoparticles or biomacromolecules between different ...
Hannes Gumz, Susanne Boye, Banu Iyisan, Vera Krönert, Petr Formanek, Brigitte Voit, Albena Lederer, Dietmar Appelhans   +7 more
doaj   +1 more source

Engineering Polymersome Protocells [PDF]

The Journal of Physical Chemistry Letters, 2011
The field of biomimicry is embracing the construction of complex assemblies that imitate both biological structure and function. Advancements in the design of these mimetics have generated a growing vision for creating an artificial or proto- cell. Polymersomes are vesicles that can be made from synthetic, biological or hybrid polymers and can be used ...
Neha P, Kamat, Joshua S, Katz, Daniel A, Hammer   +2 more
openaire   +2 more sources

Cascade Reactions in Multicompartmentalized Polymersomes [PDF]

Angewandte Chemie, 2013
AbstractEnzyme‐filled polystyrene‐b‐poly(3‐(isocyano‐L‐alanyl‐aminoethyl)thiophene) (PS‐b‐PIAT) nanoreactors are encapsulated together with free enzymes and substrates in a larger polybutadiene‐b‐poly(ethylene oxide) (PB‐b‐PEO) polymersome, forming a multicompartmentalized structure, which shows structural resemblance to the cell and its organelles. An
Peters, R.J.R.W., Marguet, M., Marais, S., Fraaije, M.W., van Hest, J.C.M., van Hest, J.C.M., Lecommandoux, S.   +6 more
openaire   +5 more sources

Programmable Budding and Fission of Janus Polymersomes for Tunable Cargo Release

Angewandte Chemie, EarlyView.
A thermodynamic framework establishes the conditions for the formation of kinetically stable Janus polymersomes using a solvent‐assisted strategy. Osmotic stress subsequently drives their membrane remodeling from reversible budding to controlled fission.
Chloé Manseau, Éloïse Equy, Prakriti Patnaik, Angela Mutschler, Emmanuel Ibarboure, Timothy P. Lodge, Sébastien Lecommandoux   +6 more
wiley   +2 more sources

A minimalistic catalytically-active cell mimetic made of a supra-molecular hydrogel encapsulated into a polymersome

, 2020
A minimalistic multicomponent cell mimetic is described consisting of a fibrillar network formed by the self-assembly of a low molecular weight compound (cytoskeleton-like) that is entrapped into a polymersome (membrane-like), namely a jelly-polymersome.
Martí-Centelles, Rosa, RUBIO-MAGNIETO, JENIFER, Escuder, Beatriu   +2 more
core   +1 more source