Results 31 to 40 of about 1,447 (174)
Photoactivated nanomotors via aggregation induced emission for enhanced phototherapy
Nature Communications, 2021 Induced motion has emerged as a method to increase the efficacy of delivery and therapeutic outcomes using nanomaterials. Here, the authors report on a Janus gold shell polymersome with aggregation-induced emission molecules for phototactic and ...
Shoupeng Cao +9 more
doaj +1 more source
Apoptosis induction and proliferation inhibition by silibinin encapsulated in nanoparticles in MIA PaCa-2 cancer cells and deregulation of some miRNAs [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): Silibinin, as an herbal compound, has anti-cancer activity. Because of low solubility of silibinin in water and body fluids, it was encapsulated in polymersome nanoparticles and its effects were evaluated on pancreatic cancer cells and ...
Fatemeh Khakinezhad Tehrani +3 more
doaj +1 more source
Design of chimaeric polymersomes
Faraday Discussions, 2005 We discuss the development of hierarchical polymer particles, or variegated polymersome composites, in which at least two different components are phase separated within one polymersome chimaera. We briefly discuss the present status in experimental polymersome research, and then discuss a speculative design strategy, based on mesoscopic simulations ...
J. G. E. M. Fraaije +4 more
openaire +3 more sources
Light-Triggered Polymersome-Based Anticancer Therapeutics Delivery
Nanomaterials, 2022 Polymersomes are biomimetic cell membrane-like model structures that are self-assembled stepwise from amphiphilic copolymers. These polymeric (nano)carriers have gained the scientific community’s attention due to their biocompatibility, versatility, and ...
Elisa Hernández Becerra +3 more
doaj +1 more source
Generating biomembrane-like local curvature in polymersomes via dynamic polymer insertion
Nature Communications, 2021 Investigating biomembrane curvature formation is important for studying intracellular processes, but the instability of liposome models mimicking these membranes restricts exploration of membrane processes.
Jiawei Sun +4 more
doaj +1 more source
Advanced Science, 2021 The challenge of effective integration and use of artificial organelles with orthogonal‐responsive membranes and their communication in eukaryotic protocells is to understand the intrinsic membrane characteristics.
Xueyi Wang +7 more
doaj +1 more source
Frontiers in Chemical Engineering, 2022 GM1 gangliosidosis is a lysosomal storage disorder caused by deficiency of β-galactosidase (βgal) and subsequent accumulation of GM1 ganglioside in lysosomes. One of the pathological aspects of GM1 gangliosidosis, and other storage disorders, is impaired
Bipin Chakravarthy Paruchuri +3 more
doaj +1 more source
The Role of Membrane Fluidization in the Gel-Assisted Formation of Giant Polymersomes. [PDF]
PLoS ONE, 2016 Polymersomes are being widely explored as synthetic analogs of lipid vesicles based on their enhanced stability and potential uses in a wide variety of applications in (e.g., drug delivery, cell analogs, etc.).
Adrienne C Greene +5 more
doaj +1 more source
Polymersome Shape Transformation at the Nanoscale [PDF]
ACS Nano, 2013 Polymer vesicles, also named polymersomes, are valuable candidates for drug delivery and micro- or nanoreactor applications. As far as drug delivery is concerned, the shape of the carrier is believed to have a strong influence on the biodistribution and cell internalization.
Salva, Romain +6 more
openaire +3 more sources
Probing and Tuning the Permeability of Polymersomes [PDF]
ACS Central Science, 2020 Polymersomes are a class of synthetic vesicles composed of a polymer membrane surrounding an aqueous inner cavity. In addition to their overall size, the thickness and composition of polymersome membranes determine the range of potential applications in which they can be employed.
Alisha J. Miller +3 more
openaire +3 more sources