Results 11 to 20 of about 2,445 (197)
Bio-Inspired Polymersome Nanoreactors [PDF]
CHIMIA, 2019 : Two key concepts in living organisms are that biochemical reactions are sequestered into reaction compartments such as cells and organelles, and that many of the complex biological reaction cascades involve transient activation of reactions in response
Omar Rifaie-Graham +2 more
doaj +11 more sources
Polymersome-Enabled Multimodal Delivery of Tobramycin and Doripenem for Targeted Eradication of Pseudomonas aeruginosa Biofilms in Chronic Rhinosinusitis. [PDF]
SmallSchematic representation of diffusion‐based versus pH‐triggered drug release within a bacterial biofilm. In diffusion‐based systems, drug cargo is gradually released independent of local pH, resulting in rapid burst release and reduced sustained concentrations.
Andresen AK +9 more
europepmc +3 more sources
Adaptive Polymersome Nanoreactors [PDF]
ChemNanoMat, 2019 Abstract Adaptive polymersome systems have gained much interest in a wide variety of research fields, ranging from cell mimics to nanomedicine, because of their high stability, tunable shape and size. Furthermore, polymersomes can be effectively transformed into nanoreactors via
Che, Hailong, van Hest, Jan C. M.
openaire +3 more sources
DNA-tethered Polymersome Clusters as Nanotheranostic Platform [PDF]
CHIMIA, 2021 Nanotheranostics combine the use of nanomaterials and biologically active compounds to achieve diagnosis and treatment at the same time. To date, severe limitations compromise the use of nanotheranostic systems as potent nanomaterials are often ...
Claire E. Meyer +4 more
doaj +2 more sources
Photopolymerization-Induced Polymersome Rupture [PDF]
Langmuir, 2019 Poly(butadiene)- b-poly(ethylene oxide) (PBut2.5- b-PEO1.3) giant polymersomes were prepared using an emulsion-centrifugation method. The impact of a fast decrease of the osmotic pressure inside the lumen of giant PBut- b-PEO vesicles was studied by confocal microscopy. This osmotic imbalance was created by performing the photoinduced polymerization of
Larnaudie, Sophie +4 more
core +4 more sources
Coarse-Grained Molecular Dynamics Modelling of a Magnetic Polymersome [PDF]
Nanomaterials, 2018 A coarse-grained molecular dynamics framework is proposed to investigate the equilibrium structure and quasi-static deformational response of a magnetic polymersome, a hollow object whose magnetoactive part is its shell (membrane).
Aleksandr Ryzhkov, Yuriy Raikher
doaj +2 more sources
Polymerization-Induced Polymersome Fusion [PDF]
Journal of the American
Chemical Society, 2019 Abstract The dynamic interactions of membranes, particularly their fusion and fission, are critical for the transmission of chemical information between cells. Fusion is primarily driven by membrane tension built up through membrane deformation.
Spyridon Varlas +5 more
openaire +4 more sources
Charge-Complementary Polymersomes for Enhanced mRNA Delivery
Pharmaceutics, 2023 Messenger RNA (mRNA) therapies have emerged as potent and personalized alternatives to conventional DNA-based therapies. However, their therapeutic potential is frequently constrained by their molecular instability, susceptibility to degradation, and ...
HakSeon Kim +5 more
doaj +1 more source
Development of Polymersomes Co-Delivering Doxorubicin and Melittin to Overcome Multidrug Resistance
Molecules, 2023 Multidrug resistance (MDR) is one of the major barriers in chemotherapy. It is often related to the overexpression of efflux receptors such as P-glycoprotein (P-gp).
Eunkyung Han +5 more
doaj +1 more source
Polymersome-based protein drug delivery – quo vadis? [PDF]
, 2022 Protein-based therapeutics are an attractive alternative to established therapeutic approaches and represent one of the fastest growing families of drugs.
Scholten, Philip B. V. +5 more
core +1 more source