Results 11 to 20 of about 1,447 (174)
Bio-Inspired Polymersome Nanoreactors [PDF]
CHIMIA, 2019 : Two key concepts in living organisms are that biochemical reactions are sequestered into reaction compartments such as cells and organelles, and that many of the complex biological reaction cascades involve transient activation of reactions in response
Omar Rifaie-Graham +2 more
doaj +6 more sources
Dynamic metastable polymersomes enable continuous flow manufacturing
Nature Communications, 2023 Polymersomes are polymeric analogues of liposomes with exceptional physical and chemical properties. Despite being dubbed as next-generation vesicles since their inception nearly three decades ago, polymersomes have yet to experience translation into the
Chin Ken Wong +2 more
doaj +1 more source
Redox-Responsive Polymersomes as Smart Doxorubicin Delivery Systems
Pharmaceutics, 2022 Stimuli-responsive polymersomes have emerged as smart drug delivery systems for programmed release of highly cytotoxic anticancer agents such as doxorubicin hydrochloride (Dox·HCl).
Carmen Ferrero +2 more
doaj +1 more source
Charge-Complementary Polymersomes for Enhanced mRNA Delivery
Pharmaceutics, 2023 Messenger RNA (mRNA) therapies have emerged as potent and personalized alternatives to conventional DNA-based therapies. However, their therapeutic potential is frequently constrained by their molecular instability, susceptibility to degradation, and ...
HakSeon Kim +5 more
doaj +1 more source
Development of Polymersomes Co-Delivering Doxorubicin and Melittin to Overcome Multidrug Resistance
Molecules, 2023 Multidrug resistance (MDR) is one of the major barriers in chemotherapy. It is often related to the overexpression of efflux receptors such as P-glycoprotein (P-gp).
Eunkyung Han +5 more
doaj +1 more source
Faraday Discussions, 2008 Polymersomes are vesicles whose membranes are comprised of self-assembled amphiphilic block co-polymers. Synthetic control of block co-polymer chemistry provides an advantageous diversity of polymersome functions, ranging from tunable materials strength, superior encaspulation of hydrophobic and hydrophilic drugs and optical dyes, and facile ...
Daniel A, Hammer +8 more
openaire +2 more sources
Molecules, 2022 Limited tissue selectivity and targeting of anticancer therapeutics in systemic administration can produce harmful side effects in the body. Various polymer nano-vehicles have been developed to encapsulate therapeutics and prevent premature drug release.
Veronika Kozlovskaya +6 more
doaj +1 more source
Polymersomes in “Gelly” Polymersomes: Toward Structural Cell Mimicry [PDF]
Langmuir, 2011 We demonstrate here the formation of compartmentalized polymersomes with an internal "gelly" cavity using an original and versatile process. Nanosize polymersomes of poly(trimethylene carbonate)-b-poly(L-glutamic acid) (PTMC-b-PGA), formed by a solvent displacement method are encapsulated with a rough "cytoplasm mimic" in giant polymersomes of poly ...
Marguet, Maïté +2 more
openaire +3 more sources
Pharmaceutics, 2021 Posterior eye tissues, such as retina, are affected in many serious eye diseases, but drug delivery to these targets is challenging due to various anatomical eye barriers.
Vijayabhaskarreddy Junnuthula +8 more
doaj +1 more source
Morphogenesis of starfish polymersomes
Nature Communications, 2023 AbstractThe enhanced membrane stability and chemical versatility of polymeric vesicles have made them promising tools in micro/nanoreactors, drug delivery, cell mimicking, etc. However, shape control over polymersomes remains a challenge and has restricted their full potential.
Jiawei Sun +7 more
openaire +5 more sources