Results 21 to 30 of about 3,624 (199)

DNA-tethered Polymersome Clusters as Nanotheranostic Platform

open access: yesCHIMIA, 2021
Nanotheranostics combine the use of nanomaterials and biologically active compounds to achieve diagnosis and treatment at the same time. To date, severe limitations compromise the use of nanotheranostic systems as potent nanomaterials are often ...
Claire E. Meyer   +4 more
doaj   +1 more source

Adaptive Polymersome Nanoreactors [PDF]

open access: yesChemNanoMat, 2019
AbstractAdaptive polymersome systems have gained much interest in a wide variety of research fields, ranging from cell mimics to nanomedicine, because of their high stability, tunable shape and size. Furthermore, polymersomes can be effectively transformed into nanoreactors via the incorporation of catalytic species. By employing polymersomes which are
Che, Hailong, van Hest, Jan C. M.
openaire   +1 more source

Polymersomes in “Gelly” Polymersomes: Toward Structural Cell Mimicry [PDF]

open access: yesLangmuir, 2011
We demonstrate here the formation of compartmentalized polymersomes with an internal "gelly" cavity using an original and versatile process. Nanosize polymersomes of poly(trimethylene carbonate)-b-poly(L-glutamic acid) (PTMC-b-PGA), formed by a solvent displacement method are encapsulated with a rough "cytoplasm mimic" in giant polymersomes of poly ...
Maïté, Marguet   +2 more
openaire   +2 more sources

Paramagnetic Porous Polymersomes [PDF]

open access: yesLangmuir, 2008
The ability of chelated Gd to serve as an effective magnetic resonance (MR) contrast agent largely depends on fast exchange rates between the Gd-bound water molecules and the surrounding bulk water. Because water diffuses slowly across lipid bilayers, liposomes with encapsulated chelated Gd have not been widely adopted as MR contrast agents.
Cheng, Zhiliang, Tsourkas, Andrew
openaire   +2 more sources

Engineering Polymersome Protocells [PDF]

open access: yesThe Journal of Physical Chemistry Letters, 2011
The field of biomimicry is embracing the construction of complex assemblies that imitate both biological structure and function. Advancements in the design of these mimetics have generated a growing vision for creating an artificial or proto- cell. Polymersomes are vesicles that can be made from synthetic, biological or hybrid polymers and can be used ...
Neha P, Kamat   +2 more
openaire   +2 more sources

DENV-Mimetic Polymersome Nanoparticles Bearing Multi-Epitope Lipopeptides Antigen as the Next-Generation Dengue Vaccine

open access: yesPharmaceutics, 2022
Dengue remains a severe threat to public health. The safety and efficacy of the licensed dengue vaccine is not clinically satisfactory, which necessitate the need of new approach in designing an effective dengue vaccine without eliciting adverse reaction.
Nur Adilah Abdul Rahman   +7 more
doaj   +1 more source

Intravitreal Polymeric Nanocarriers with Long Ocular Retention and Targeted Delivery to the Retina and Optic Nerve Head Region

open access: yesPharmaceutics, 2021
Posterior eye tissues, such as retina, are affected in many serious eye diseases, but drug delivery to these targets is challenging due to various anatomical eye barriers.
Vijayabhaskarreddy Junnuthula   +8 more
doaj   +1 more source

A new approach to high resolution, high contrast electron microscopy of macromolecular block copolymer assemblies [PDF]

open access: yes, 2013
Determining the structure of macromolecular samples is vital for understanding and adapting their function. Transmission electron microscopy (TEM) is widely used to achieve this, but, owing to the weak electron scattering cross-section of carbon, TEM ...
Allen   +36 more
core   +1 more source

“Clickable” polymersomes

open access: yesChemical Communications, 2007
Polymersomes, composed of amphiphilic polystyrene-block-poly(acrylic acid) (PS-b-PAA), with the periphery being covered with azide groups, were used for further functionalization using "click" chemistry.
Opsteen, J.A.   +4 more
openaire   +3 more sources

A novel diblock copolymer of (monomethoxy poly [ethylene glycol]-oleate) with a small hydrophobic fraction to make stable micelles/polymersomes for curcumin delivery to cancer cells [PDF]

open access: yes, 2014
Curcumin is a potent natural anticancer agent, but its effectiveness is limited by properties such as very low solubility, high rate of degradation, and low rate of absorption of its hydrophobic molecules in vivo.
Erfani-Moghadam, V.   +5 more
core   +2 more sources

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