Results 41 to 50 of about 2,445 (197)
Multicompartment polymersome gel for encapsulation [PDF]
, 2011 We introduce an approach that combines the concepts of emulsion-templating and dewetting for fabricating polymersomes with a large number of compartments.
Weitz, DA +3 more
core +1 more source
Angewandte Chemie, EarlyView.This work presents a thermodynamically programmable nanoplatform based on calixarenes that enables precise, tunable drug loading and release with broad applicability. Across diverse drugs and ratios, both loading and delivery matched preset values with > 95% accuracy in cells and tumors.
Yu‐Chen Pan +9 more
wiley +2 more sources
The Nature of Cell‐Penetrating Poly(disulfide)s
Angewandte Chemie, EarlyView.The mode of action of cell‐penetrating poly(disulfide)s (CPDs) is elucidated to understand thiol‐mediated uptake (TMU) in general and guide future efforts to control cellular entry for chemicals delivery and pathogen defense. ABSTRACT Cell‐penetrating poly(disulfide)s (CPDs) are the most popular thiol‐mediated uptake (TMU) tools for delivering attached
Saidbakhrom Saidjalolov +7 more
wiley +2 more sources
Photoactivated nanomotors via aggregation induced emission for enhanced phototherapy
Nature Communications, 2021 Induced motion has emerged as a method to increase the efficacy of delivery and therapeutic outcomes using nanomaterials. Here, the authors report on a Janus gold shell polymersome with aggregation-induced emission molecules for phototactic and ...
Shoupeng Cao +9 more
doaj +1 more source
Design of chimaeric polymersomes
Faraday Discussions, 2005 We discuss the development of hierarchical polymer particles, or variegated polymersome composites, in which at least two different components are phase separated within one polymersome chimaera. We briefly discuss the present status in experimental polymersome research, and then discuss a speculative design strategy, based on mesoscopic simulations ...
J. G. E. M. Fraaije +4 more
openaire +3 more sources
Apoptosis induction and proliferation inhibition by silibinin encapsulated in nanoparticles in MIA PaCa-2 cancer cells and deregulation of some miRNAs [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): Silibinin, as an herbal compound, has anti-cancer activity. Because of low solubility of silibinin in water and body fluids, it was encapsulated in polymersome nanoparticles and its effects were evaluated on pancreatic cancer cells and ...
Fatemeh Khakinezhad Tehrani +3 more
doaj +1 more source
, 2022 <p>Research data supporting Rifaie-Graham et al. "Photoswitchable gating of non-equilibrium enzymatic feedback in chemically communicating polymersome nanoreactors."Nature Chemistry. 2022.
Wang, Richard +13 more
core +1 more source
Generating biomembrane-like local curvature in polymersomes via dynamic polymer insertion
Nature Communications, 2021 Investigating biomembrane curvature formation is important for studying intracellular processes, but the instability of liposome models mimicking these membranes restricts exploration of membrane processes.
Jiawei Sun +4 more
doaj +1 more source
Light-Triggered Polymersome-Based Anticancer Therapeutics Delivery
Nanomaterials, 2022 Polymersomes are biomimetic cell membrane-like model structures that are self-assembled stepwise from amphiphilic copolymers. These polymeric (nano)carriers have gained the scientific community’s attention due to their biocompatibility, versatility, and ...
Elisa Hernández Becerra +3 more
doaj +1 more source
Advanced Science, 2021 The challenge of effective integration and use of artificial organelles with orthogonal‐responsive membranes and their communication in eukaryotic protocells is to understand the intrinsic membrane characteristics.
Xueyi Wang +7 more
doaj +1 more source