Results 71 to 80 of about 2,445 (197)
Molecular engineering of polymersome surface topology [PDF]
, 2016 Biological systems exploit self-assembly to create complex structures whose arrangements are finely controlled from the molecular to mesoscopic level. We report an example of using fully synthetic systems that mimic two levels of self-assembly.
Gaitzsch, J +13 more
core +1 more source
Near-Infrared Laser-Triggered, Self-Immolative Smart Polymersomes for in vivo Cancer Therapy
International Journal of Nanomedicine, 2020 Qing Tang,* Ping Hu,* Haibo Peng, Ning Zhang, Qiang Zheng, Yun He School of Pharmaceutical Sciences and Chongqing Key Laboratory of Natural Drug Research, Chongqing University, Chongqing 401331, People’s Republic of China*These authors contributed ...
Tang Q +5 more
doaj
Shaping polymersomes into predictable morphologies via out-of-equilibrium self-assembly
Nature Communications, 2016 Polymersomes are used in many applications, ranging from drug delivery to microfluidics, but controlling their shape is difficult. Here, Christianen and co-workers have precisely controlled polymersome shape via an out-of-equilibrium process and fully ...
R. S. M. Rikken +6 more
doaj +1 more source
Expression of Human CYP2D6 in Artificial Cells Based on Polymer‐Lipid Hybrid Vesicles
ChemBioChem, Volume 27, Issue 21, 12 November 2026.Expression of eGFP and human cytochrome P450 2D6 (CYP2D6) within the lumen of giant polymer‐lipid hybrid vesicles using a Leishmania tarentolae‐based cell‐free protein expression system is illustrated. Both proteins were expressed in the vesicle lumen, and low‐polymer‐content hybrid vesicles were the most suitable scaffolds for CYP2D6 expression with ...
Sarah Dahl +7 more
wiley +1 more source
Programmable Enzymatic Reaction Network in Artificial Cell‐Like Polymersomes
Advanced ScienceThe ability to precisely control in vitro enzymatic reactions in synthetic cells plays a crucial role in the bottom‐up design of artificial cell models that can recapitulate the key cellular features and functions such as metabolism. However, integration
Hanjin Seo, Hyomin Lee
doaj +1 more source
PharmaceuticsIn this study, three new 3,7-dihydroxyflavone (1) derivatives with different sugars were designed and synthesised by click chemistry. Click chemistry requires the previously modification of building blocks with azide and alkyne groups and therefore, the ...
Nuno M. Saraiva +6 more
doaj +1 more source
Curcumin Intervention in Diabetic Neuropathy: Molecular Mechanisms and Preclinical Insights
Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.This review highlights curcumin's neuroprotective potential, showing how it mitigates oxidative stress and inflammation by modulating Nrf2, MAPK, and NF‐κB signaling. Preclinical data shows it stabilizes glucose metabolism and reduces nerve degradation.
Sanket Sharma +5 more
wiley +1 more source
Microfluidic production of monodisperse food‐additive polymer capsules for biological applications
Droplet, Volume 5, Issue 4, October 2026.Monodisperse TGPR polymer capsules are generated via a robust microfluidic approach exploiting droplet interface transfer across the oil‒water interface. Unlike lipid vesicles, these capsules offer high thermal stability and biocompatibility. They successfully demonstrated utility as robust bioreactors for in‐capsule PCR and bacterial cultivation ...
Yuki Gondo +5 more
wiley +1 more source
Tailoring Polymersome Shape Using the Hofmeister Effect
, 2019 Reshaping polymersomes remains a challenge for both size and shape control, methodology development, and mechanism understanding, which hindered their application in nanomedicine and nanomachine.
Wei Li (7081) +4 more
core +1 more source
Energetic and Entropic Motifs in Vesicle Morphogenesis in Amphiphilic Diblock Copolymer Solutions
Colloids and InterfacesCoarse-grained molecular dynamic simulations are employed to investigate the spatiotemporal evolution of vesicles (polymersomes) via self-assembly of randomly distributed amphiphilic diblock copolymers PB-PEO (Poly(Butadiene)-b-Poly(Ethylene Oxide)) in ...
Senyuan Liu, Radhakrishna Sureshkumar
doaj +1 more source