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Architecture-Encoded Degradation Kinetics and Pathways through the Shape and Size of Polymeric Vesicles. [PDF]
J Am Chem SocWang D, Luan J, White PB, Wilson DA.
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Journal of the American Chemical Society, 2020
Hollow nanoparticles such as polymersomes have promising potentials in many fields. However, the design and construction of higher-order polymersomes with precisely controlled spatial compartments is still very challenging. Herein, we report a unique tetrapod polymersome that is assembled by the controlled fusion of four traditional spherical ...
Jiangang Xiao, Jianzhong Du
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Hollow nanoparticles such as polymersomes have promising potentials in many fields. However, the design and construction of higher-order polymersomes with precisely controlled spatial compartments is still very challenging. Herein, we report a unique tetrapod polymersome that is assembled by the controlled fusion of four traditional spherical ...
Jiangang Xiao, Jianzhong Du
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Annual Review of Biomedical Engineering, 2006
Polymersomes are self-assembled polymer shells composed of block copolymer amphiphiles. These synthetic amphiphiles have amphiphilicity similar to lipids, but they have much larger molecular weights, so for this reason—along with others reviewed here—comparisons of polymersomes with viral capsids composed of large polypeptide chains are highly ...
Discher, Dennis E, Ahmed, Fariyal
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Polymersomes are self-assembled polymer shells composed of block copolymer amphiphiles. These synthetic amphiphiles have amphiphilicity similar to lipids, but they have much larger molecular weights, so for this reason—along with others reviewed here—comparisons of polymersomes with viral capsids composed of large polypeptide chains are highly ...
Discher, Dennis E, Ahmed, Fariyal
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Polymersomes in Polymersomes: Multiple Loading and Permeability Control
Angewandte Chemie International Edition, 2011With such a compartmentalized structure, a mol-ecule encapsulated in the inner liposome, would have topermeate through two successive membranes, instead of asingle one before leaking into the outside environment. Thisdouble-membrane effect was demonstrated by observing theserumhalf-lifeofciprofloxacindrugincreasingfrom10 mininsingle liposomes to 6 h in
Maïté, Marguet +2 more
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Polymersomes: Preparation and Characterization
2019Polymersomes, also called polymeric vesicles, are self-assembled by amphiphilic copolymers. Due to their unique characters, polymersomes are attracting more and more interest as an important class of vehicles for nanopharmaceuticals. In this chapter, various methods to prepare and characterize polymersomes are introduced systematically with several ...
Yumiao, Hu, Liyan, Qiu
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Citation: 'polymersome' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13848 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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Detergent-Aided Polymersome Preparation
Biomacromolecules, 2010Until now, most preparative methods used to form polymeric vesicles involve either organic cosolvents or sonication. In this communication, we demonstrate for the first time a detergent-aided method to produce polymersomes. Peptidic polymersomes were formed from the rod-rod block copolymer PBLG(36)-E, where PBLG is hydrophobic poly(gamma-benzyl l ...
Marsden H. R. +5 more
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J. Mater. Chem. B, 2014
A multicompartment cascade reaction is presented in a polymersome-in-polymersome architecture, which is regulated by insertion of a channel protein in the inner compartment's polymer membrane.
Winna, Siti +6 more
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A multicompartment cascade reaction is presented in a polymersome-in-polymersome architecture, which is regulated by insertion of a channel protein in the inner compartment's polymer membrane.
Winna, Siti +6 more
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