Results 141 to 150 of about 1,447 (174)
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Nachrichten aus der Chemie, 2012
AbstractPolymersome sind artifizielle Strukturen, die das Bauprinzip der Liposomen nutzen. Sie eignen sich unter anderem als Wirkstofftransporter und als Nanoreaktoren für Biomedizin und Biotechnik.
Jens Gaitzsch +2 more
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AbstractPolymersome sind artifizielle Strukturen, die das Bauprinzip der Liposomen nutzen. Sie eignen sich unter anderem als Wirkstofftransporter und als Nanoreaktoren für Biomedizin und Biotechnik.
Jens Gaitzsch +2 more
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Journal of Drug Delivery Science and Technology, 2013
In spite of the clear potential of personalized medicine, its pace of implementation has not yet fulfilled initial hopes. Polymeric vesicles, also named polymersomes, are presented as versatile systems able to address issues of efficacy, specificity and controlled release of drugs in a wide range of pathological scenarios that might show the way to ...
J. Thevenot +2 more
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In spite of the clear potential of personalized medicine, its pace of implementation has not yet fulfilled initial hopes. Polymeric vesicles, also named polymersomes, are presented as versatile systems able to address issues of efficacy, specificity and controlled release of drugs in a wide range of pathological scenarios that might show the way to ...
J. Thevenot +2 more
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Sequential Synthesis of Coordination Polymersomes
Angewandte Chemie International Edition, 2014AbstractNovel organic–inorganic hybrid liposomes, so‐called coordination polymersomes (CPsomes), with artificial domains that exhibit strong lateral cohesion were prepared by a three‐step procedure that formed a coordinative interaction leading to a lipid bilayer.
Ryo, Ohtani +6 more
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2013
Amphiphilic block copolymers represent a major field of research in the design and creation of innovative materials for biomedical applications. Self-directed assemblies of such copolymers have been of great value in the development of novel drug delivery systems.
Núria Sancho Oltra +5 more
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Amphiphilic block copolymers represent a major field of research in the design and creation of innovative materials for biomedical applications. Self-directed assemblies of such copolymers have been of great value in the development of novel drug delivery systems.
Núria Sancho Oltra +5 more
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Covalent Attachment of Polymersomes to Surfaces
Langmuir, 2010We show that vesicles made of block copolymers with aldehyde end groups can be covalently attached to aminated and non-aminated, untreated glass surfaces. The attached vesicles were sufficiently stable to allow a detailed investigation of vesicle shapes by confocal laser scanning microscopy (CLSM) and AFM in aqueous solutions allowing reconstruction of
Stephanie, Domes +4 more
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Adhesion of Antibody-Functionalized Polymersomes
Langmuir, 2006Polymersomes are vesicles made from synthetic block copolymers. The adhesiveness of micron-sized polymersomes, functionalized with antibodies that bind to vascular cell adhesion molecules, which could be useful for vascular targeting, was measured. Intercellular adhesion molecule-1 (ICAM-1) is an endothelial cell adhesion molecule whose expression ...
John J, Lin +3 more
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A review of polypeptide-based polymersomes
Biomaterials, 2014Self-assembled systems from biodegradable amphiphilic polymers at the nanometer scale, such as nanotubes, nanoparticles, polymer micelles, nanogels, and polymersomes, have attracted much attention especially in biomedical fields. Among these nano-aggregates, polymersomes have attracted tremendous interests as versatile carriers due to their colloidal ...
Lanxia, Zhao +5 more
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Membrane Stabilization of Biodegradable Polymersomes
Langmuir, 2009Biodegradable polymersomes are promising vehicles for a range of applications. Their stabilization would improve many properties, including the retention and controlled release of polymersome contents, yet this has not been previously accomplished. Here, we present the first example of stabilizing fully biodegradable polymersomes through acrylation of ...
Joshua S, Katz +5 more
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Structural and mechanical characteristics of polymersomes
Soft Matter, 2014Polymersomes self-assembled from amphiphilic macromolecules have attracted growing attention because of their multifunctionality and stability. By controlling the structural characteristics of polymersomes, including vesicle shape, size, and membrane thickness, their mechanical and transport properties as well as their fusion behavior can be ...
Hung-Yu, Chang +2 more
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Can Polymersomes Form Colloidosomes?
Journal of the American Chemical Society, 2012Hydroxy-functionalized polymersomes (or block copolymer vesicles) were prepared via a facile one-pot RAFT aqueous dispersion polymerization protocol and evaluated as Pickering emulsifiers for the stabilization of emulsions of n-dodecane emulsion droplets in water.
Thompson, K +3 more
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