Results 161 to 170 of about 2,445 (197)

Polymersomes in Polymersomes: Multiple Loading and Permeability Control

Angewandte Chemie International Edition, 2011
With such a compartmentalized structure, a mol-ecule encapsulated in the inner liposome, would have topermeate through two successive membranes, instead of asingle one before leaking into the outside environment. Thisdouble-membrane effect was demonstrated by observing theserumhalf-lifeofciprofloxacindrugincreasingfrom10 mininsingle liposomes to 6 h in
Marguet, Maïté, Edembe, Lise, Lecommandoux, Sébastien   +2 more
openaire   +2 more sources

Polymersomes: Preparation and Characterization

2019
Polymersomes, also called polymeric vesicles, are self-assembled by amphiphilic copolymers. Due to their unique characters, polymersomes are attracting more and more interest as an important class of vehicles for nanopharmaceuticals. In this chapter, various methods to prepare and characterize polymersomes are introduced systematically with several ...
Yumiao, Hu, Liyan, Qiu
openaire   +2 more sources

Detergent-Aided Polymersome Preparation

Biomacromolecules, 2010
Until now, most preparative methods used to form polymeric vesicles involve either organic cosolvents or sonication. In this communication, we demonstrate for the first time a detergent-aided method to produce polymersomes. Peptidic polymersomes were formed from the rod-rod block copolymer PBLG(36)-E, where PBLG is hydrophobic poly(gamma-benzyl l ...
Marsden H. R., Quer C. B., Sanchez E. Y., Gabrielli L., Jiskoot W., Kros A.   +5 more
openaire   +2 more sources

An intercompartmental enzymatic cascade reaction in channel-equipped polymersome-in-polymersome architectures

J. Mater. Chem. B, 2014
A multicompartment cascade reaction is presented in a polymersome-in-polymersome architecture, which is regulated by insertion of a channel protein in the inner compartment's polymer membrane.
Winna, Siti, Hans-Peter M, de Hoog, Ozana, Fischer, Wong Yee, Shan, Nikodem, Tomczak, Madhavan, Nallani, Bo, Liedberg   +6 more
openaire   +2 more sources

Responsive Polymersome

Nachrichten aus der Chemie, 2012
AbstractPolymersome sind artifizielle Strukturen, die das Bauprinzip der Liposomen nutzen. Sie eignen sich unter anderem als Wirkstofftransporter und als Nanoreaktoren für Biomedizin und Biotechnik.
Jens Gaitzsch, Dietmar Appelhans, Brigitte Voit   +2 more
openaire   +1 more source

Polymersomes for theranostics

Journal of Drug Delivery Science and Technology, 2013
In spite of the clear potential of personalized medicine, its pace of implementation has not yet fulfilled initial hopes. Polymeric vesicles, also named polymersomes, are presented as versatile systems able to address issues of efficacy, specificity and controlled release of drugs in a wide range of pathological scenarios that might show the way to ...
J. Thevenot, H. Oliveira, S. Lecommandoux   +2 more
openaire   +1 more source

Sequential Synthesis of Coordination Polymersomes

Angewandte Chemie International Edition, 2014
AbstractNovel organic–inorganic hybrid liposomes, so‐called coordination polymersomes (CPsomes), with artificial domains that exhibit strong lateral cohesion were prepared by a three‐step procedure that formed a coordinative interaction leading to a lipid bilayer.
Ryo, Ohtani, Munehiro, Inukai, Yuh, Hijikata, Tetsuya, Ogawa, Mikihito, Takenaka, Masaaki, Ohba, Susumu, Kitagawa   +6 more
openaire   +2 more sources

Polymersomes and Filomicelles

2013
Amphiphilic block copolymers represent a major field of research in the design and creation of innovative materials for biomedical applications. Self-directed assemblies of such copolymers have been of great value in the development of novel drug delivery systems.
Núria Sancho Oltra, Sharon M. Loverde, Takamasa Harada, Abdullah Mahmud, Karthikan Rajagopal, Dennis E. Discher   +5 more
openaire   +1 more source

A review of polypeptide-based polymersomes

Biomaterials, 2014
Self-assembled systems from biodegradable amphiphilic polymers at the nanometer scale, such as nanotubes, nanoparticles, polymer micelles, nanogels, and polymersomes, have attracted much attention especially in biomedical fields. Among these nano-aggregates, polymersomes have attracted tremendous interests as versatile carriers due to their colloidal ...
Lanxia, Zhao, Nuannuan, Li, Kaiming, Wang, Chunhuan, Shi, Longlong, Zhang, Yuxia, Luan   +5 more
openaire   +2 more sources

Membrane Stabilization of Biodegradable Polymersomes

Langmuir, 2009
Biodegradable polymersomes are promising vehicles for a range of applications. Their stabilization would improve many properties, including the retention and controlled release of polymersome contents, yet this has not been previously accomplished. Here, we present the first example of stabilizing fully biodegradable polymersomes through acrylation of ...
Joshua S, Katz, Dalia H, Levine, Kevin P, Davis, Frank S, Bates, Daniel A, Hammer, Jason A, Burdick   +5 more
openaire   +2 more sources