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Detergent-Aided Polymersome Preparation
Biomacromolecules, 2010Until now, most preparative methods used to form polymeric vesicles involve either organic cosolvents or sonication. In this communication, we demonstrate for the first time a detergent-aided method to produce polymersomes. Peptidic polymersomes were formed from the rod-rod block copolymer PBLG(36)-E, where PBLG is hydrophobic poly(gamma-benzyl l ...
Marsden H. R. +5 more
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Nachrichten aus der Chemie, 2012
AbstractPolymersome sind artifizielle Strukturen, die das Bauprinzip der Liposomen nutzen. Sie eignen sich unter anderem als Wirkstofftransporter und als Nanoreaktoren für Biomedizin und Biotechnik.
Jens Gaitzsch +2 more
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AbstractPolymersome sind artifizielle Strukturen, die das Bauprinzip der Liposomen nutzen. Sie eignen sich unter anderem als Wirkstofftransporter und als Nanoreaktoren für Biomedizin und Biotechnik.
Jens Gaitzsch +2 more
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Can Polymersomes Form Colloidosomes?
Journal of the American Chemical Society, 2012Hydroxy-functionalized polymersomes (or block copolymer vesicles) were prepared via a facile one-pot RAFT aqueous dispersion polymerization protocol and evaluated as Pickering emulsifiers for the stabilization of emulsions of n-dodecane emulsion droplets in water.
Thompson, Kate L. +3 more
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Renoprotective Angiographic Polymersomes
Advanced Functional Materials, 2020AbstractComputed tomography (CT) angiography is powerful for the diagnosis of vascular diseases. Unfortunately, this method usually requires a high dosage of iodinated contrast agents, which can lead to severe elevation of reactive oxygen species (ROS) levels within kidneys.
Danqing Liu +2 more
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Polymersome-Embedded Nanoparticles
Macromolecular Symposia, 2007AbstractSummary: Polymersomes are self assembled vesicles composed of fully synthetic amphiphilic diblock copolymers. Many of their properties are similar to lipid vesicles, although with often higher thermal and mechanical stability within their curved membrane. Incorporation of nanosized objects into their hydrophilic interior or hydrophobic membrane
Robert Sachsenhofer +3 more
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Multicompartment Polymersomes from Double Emulsions
Angewandte Chemie International Edition, 2011Versatile chambers: A microfluidic technique is used to generate polymersomes with multiple compartments using double emulsions with different morphology as templates (see scheme). The polymersomes could be utilized for encapsulation of multiple substances and as reaction vessels that enable triggered reaction with controlled stoichometry of the ...
Kim, SH, Shum, HC, Weitz, DA, Zhao, YJ
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Polymersomes: Preparation and Characterization
2019Polymersomes, also called polymeric vesicles, are self-assembled by amphiphilic copolymers. Due to their unique characters, polymersomes are attracting more and more interest as an important class of vehicles for nanopharmaceuticals. In this chapter, various methods to prepare and characterize polymersomes are introduced systematically with several ...
Yumiao, Hu, Liyan, Qiu
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Sequential Synthesis of Coordination Polymersomes
Angewandte Chemie International Edition, 2014AbstractNovel organic–inorganic hybrid liposomes, so‐called coordination polymersomes (CPsomes), with artificial domains that exhibit strong lateral cohesion were prepared by a three‐step procedure that formed a coordinative interaction leading to a lipid bilayer.
Ryo, Ohtani +6 more
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Membrane Stabilization of Biodegradable Polymersomes
Langmuir, 2009Biodegradable polymersomes are promising vehicles for a range of applications. Their stabilization would improve many properties, including the retention and controlled release of polymersome contents, yet this has not been previously accomplished. Here, we present the first example of stabilizing fully biodegradable polymersomes through acrylation of ...
Joshua S, Katz +5 more
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Journal of Drug Delivery Science and Technology, 2013
In spite of the clear potential of personalized medicine, its pace of implementation has not yet fulfilled initial hopes. Polymeric vesicles, also named polymersomes, are presented as versatile systems able to address issues of efficacy, specificity and controlled release of drugs in a wide range of pathological scenarios that might show the way to ...
J. Thevenot +2 more
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In spite of the clear potential of personalized medicine, its pace of implementation has not yet fulfilled initial hopes. Polymeric vesicles, also named polymersomes, are presented as versatile systems able to address issues of efficacy, specificity and controlled release of drugs in a wide range of pathological scenarios that might show the way to ...
J. Thevenot +2 more
openaire +1 more source