Results 211 to 220 of about 3,539,255 (350)

Impact of Renin-Angiotensin-Aldosterone System (RAAS) Gene Polymorphism in Essential Hypertension and Antihypertensive Drug Therapy: A Review. [PDF]

Int J Hypertens
Adhikari A, Sharma C, Lhamu Sherpa M, Karaunakran G, Dhakal M, Sharma A.   +5 more
europepmc   +1 more source

JA‐Mediated Regulation of Amino Acid Homeostasis Adjusts Metabolic Flux and Enhances Spider Mite Tolerance via the SlJAZ8‐SlWRKY57‐SlAVT6s Module in Tomato

Advanced Science, EarlyView.
This study elucidates a novel SlJAZ8‐SlWRKY57‐SlAVT6A/SlAVT6B module that effectively channels metabolic flux from primary to secondary metabolism, impacting plant growth, development, and resistance. Two novel vacuolar amino acid exporters, SlAVT6A and SlAVT6B, fine‐tunes trichomes, terpenes, and gibberellins, bolstering spider mite resistance.
Yingchen Hao, Xiaolong Wang, Langchen Guo, Lijun Xiang, Enxi Luo, Peng Cao, Penghui Liu, Yue Zhong, Chun Li, Jun Lai, Jun Yang, Shouchuang Wang   +11 more
wiley   +1 more source

Impact of IGFBP-3 A-202C genetic variant on breast cancer susceptibility and serum biomarkers (IGFBP-3 and IGF-1) in Palestinian women. [PDF]

PLoS One
Arafat HM, Al-Astani TAD, Shafii N, Muhamad R, Shamallakh OM, Naser I, Al Laham N, Siddig A.   +7 more
europepmc   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source

Importance of selected genetic determinants on endurance performance and physical strength: a narrative review. [PDF]

Front Physiol
Yao J, Saraf F, Rathore VS, Darkazanli K, Liu Y, Korivi M, Bhaskar LVKS.   +6 more
europepmc   +1 more source

GbSER02 Interacts With GhVOZ1 to Promote Fiber Elongation by Modulating Gibberellin Synthesis in Cotton

Advanced Science, EarlyView.
GbSER02 with a single base change (SNP517G) encodes normal serpin protein and interacts with transcription factor VOZ1 to alleviate the repression of VOZ1 on GA3ox1 and promote GA3 biosynthesis. Further, GA3 induces the expression of cell wall loosening‐related genes and decreases flavonoid content, ultimately facilitating fiber cell elongation in ...
Hao Jia, Dongmei Zhang, Qishen Gu, Yanbin Li, Jing Li, Wannian Li, Zhengwen Sun, Huifeng Ke, Jun Yang, Liqiang Wu, Yan Zhang, Zhiying Ma, Xingfen Wang   +12 more
wiley   +1 more source

<i>COL5A1</i> rs13946 Polymorphism and Anterior Cruciate Ligament Injury: Systematic Review and Meta-Analysis. [PDF]

Int J Mol Sci
Sun Z, Cięszczyk P, Bojarczuk A.
europepmc   +1 more source

Facile Synthesis of Nanolayered Manganese Oxide for the Efficient and Selective Removal of Strontium(II) from Nuclear Wastewater

Advanced Science, EarlyView.
A novel nanolayered manganese oxide material (Na‐NLMO) is prepared using a rapid and straightforward method for efficient adsorption of Sr(II) in both simulated waste liquid and natural water systems. Its excellent adsorption performance of Na‐NLMO could be attributed to the accessible layered structure and negatively charged framework.
Fan Wang, Qi Zheng, Wenya Tai, Qiang Wu, Xinglei Li, Yehuizi Wu, Ningchao Zheng, Shunyan Ning, Deqian Zeng, Hiroshi Watabe, Yan Wu, Hai Li, Yuezhou Wei, Xiangbiao Yin   +13 more
wiley   +1 more source

Accounting for ALA Natural Mutations Enhances the Efficiency of Graphene Oxide Nanopriming in Bar‐Modified Arabidopsis

Advanced Science, EarlyView.
Nanopriming enhances plant resilience to environmental challenges; however, its effectiveness across diverse genetic backgrounds, including genetic modifications and natural variations, remains uncertain. These findings demonstrate that nanopriming improves efficacy when natural genetic variations are considered, particularly in genetically modified ...
Yining Wu, Rui Sun, Yueting Cui, Jun Qiao, Chengdong Zhang   +4 more
wiley   +1 more source

Genetic variability in sodium-glucose cotransporter 2 and glucagon-like peptide 1 receptor effect on glycemic and pressure control in type 2 diabetes patients treated with SGLT2 inhibitors and GLP-1RA in the everyday clinical practice. [PDF]

Front Endocrinol (Lausanne)
Tonin G, Goričar K, Blagus T, Janež A, Dolžan V, Klen J.   +5 more
europepmc   +1 more source