Results 241 to 250 of about 666,024 (276)

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

Advanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu, Jialiang Luo, Haoyuan Qiu, Weijie Shao, Yueyang Lu, Meixuan Luo, Zhaofeng Lin, Yan Zhang, Libo Zhang, Hong Wang, Jia Zhou, Guangfeng Ruan, Peihua Cao, Daming Zuo   +13 more
wiley   +1 more source

Methylenetetrahydrofolate Reductase and Methionine Synthase Reductase Polymorphisms: Genetic Predictors of Congenital Heart Disease Subtypes. [PDF]

Cureus
Tripathi S, Awasthi S, Tripathi S, Jain A, Sharma AK.   +4 more
europepmc   +1 more source

Uncoupling Metastasis and Epithelial‐to‐Mesenchymal Transition in sgP19/kRAS‐Driven Spontaneous Metastatic Liver Tumor Model

Advanced Science, EarlyView.
The article first reported that a murine mixed typical intrahepatic cholangiocarcinoma (iCCA)/sarcomatoid iCCA liver tumor model with 100% incidence of spontaneous extrahepatic metastasis and confirmed the occurrence of in mouse iCCA. Most importantly, EMT induced by the TGF‐β/ZEB1 axis does not influence tumor development or distant metastasis in this
Jingwen Wang, Zijing Xu, Lei Xu, Lishan Wang, Jiahao Geng, Xue Wang, Meng Xu, Daphne Superville, Melissa Reeves, Matthias Evert, Diego F. Calvisi, Xin Chen, Xinhua Song   +12 more
wiley   +1 more source

Molecular Evidence of Clonal <i>Salmonella</i> Enteritidis Persistence in Poultry Cold-Chain Environments Under Environmental Stress. [PDF]

Foods
Gazi KS, Alshehri WA, Alkhammash AM, Alqadri N, Bahwerth FS, Baty RS, Albakri NN, Khalel AF, Alpakistany TA, Melebari M.   +9 more
europepmc   +1 more source

Impact of SLCO1B1 (rs2306283) polymorphism on personalized atorvastatin dosing in a genetically distinct South Asian cohort. [PDF]

BMC Pharmacol Toxicol
Farooq T, Naeem U, Siddique A, Kausar S, Waheed A, Mumal S.   +5 more
europepmc   +1 more source

A public mid-density genotyping platform for cultivated cranberry (Vaccinium macrocarpon Aiton). [PDF]

Plant Genome
Chen S, Lin M, Taniguti CH, Tang X, de la Torre F, Sideli GM, Iorizzo M, Edger PP, Neyhart J, Zalapa J, Bassil N, Heller-Uszynska K, Zhao D, Beil CT, Sheehan MJ.   +14 more
europepmc   +1 more source

Genetic Testing in Periodontitis: A Narrative Review on Current Applications, Limitations, and Future Perspectives. [PDF]

Genes (Basel)
Modafferi C, Grippaudo C, Corvaglia A, Cristi V, Amato M, Rigotti P, Polizzi A, Isola G.   +7 more
europepmc   +1 more source

GLIS3 rs7034200 and ADRB3 rs4994 genetic variants associated with an increased risk of gestational diabetes mellitus in Chinese women: a case-control study. [PDF]

BMC Pregnancy Childbirth
Shui L, Liu Q, Liu X, Bai H, Wu Y, Sheng Y, He G, Fan P.   +7 more
europepmc   +1 more source

Impact of cytochrome P450 3A5 expression on clinical outcomes in renal transplant recipients receiving tacrolimus-based immunosuppression. [PDF]

World J Transplant
Pasari AS, Malde S, Tolani P, Ramteke V, Gupta S, Pawar T, Jeyachandran V, Sejpal K, Kurundwadkar M, Gurjar P, Kashiv P, Dubey S, Bawankule C, Kute VB, Deshpande N, Balwani MR.   +15 more
europepmc   +1 more source