Results 231 to 240 of about 145,434 (315)

Recent Statistical Innovations in Human Genetics

open access: yesAnnals of Human Genetics, EarlyView.
ABSTRACT We review three areas of human genetics that have been developed in the past few decades, in which statistical innovation has made a crucial contribution with recent important advances and the potential for further rapid progress. The first topic is the development of mathematical models for the genealogy underlying samples of genome‐wide ...
David J. Balding, Doug Speed
wiley   +1 more source

Pharmacogenetics of follicle‐stimulating hormone action in the male

open access: yesAndrology, EarlyView.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani   +7 more
wiley   +1 more source

Assessment of the molecular mechanisms of drug‐induced hidden cardiotoxicity by a multi‐omics approach: The example of rofecoxib

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Hidden cardiotoxicity is defined as drug‐induced cardiotoxicity that becomes obvious only in the presence of comorbidities. However, the molecular mechanisms of hidden cardiotoxicity are not always known. Therefore, unbiased multi‐omics approaches could assist in revealing regulatory pathways.
Bennet Y. Weber   +12 more
wiley   +1 more source

Global consequences of dam‐induced river fragmentation on diadromous migrants: a systematic review and meta‐analysis

open access: yesBiological Reviews, EarlyView.
ABSTRACT The global proliferation of dams has altered flow and sediment regimes in rivers, presenting a major threat to freshwater biodiversity. Diadromous species, such as fishes, decapod crustaceans and gastropods, are particularly susceptible to fragmentation because dams obstruct their breeding migrations between coastal waters and rivers. Although
Jeffery C. F. Chan   +3 more
wiley   +1 more source

Association of MMP-11 Genotypes With Colorectal Cancer in Taiwan. [PDF]

open access: yesIn Vivo
Ke TW   +9 more
europepmc   +1 more source

Prenatal Cell‐Free DNA Screening With Fetal Enrichment Enables Sampling From 8 Weeks of Gestational Age

open access: yesClinical Genetics, EarlyView.
Fetal fraction (FF) estimates for 170 male pregnancies sampled between 7w0d and 9w6d of GA as a function of gestational age at blood draw without (blue triangles) and with fetal enrichment (red dots). Regression lines are shown (gray 95% CI). Besides, there is a closer look at samples below 4% FF.
Seyedeh Saideh Daryabari   +6 more
wiley   +1 more source

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