Results 101 to 110 of about 306,247 (295)

Effect of a single nucleotide polymorphism in miR-146a on COX-2 protein expression and lung function in smokers with chronic obstructive pulmonary disease [PDF]

, 2015
Ran Wang,1,* Min Li,2,* Sijing Zhou,1,3 Daxiong Zeng,4 Xuan Xu,5 Rui Xu,1 Gengyun Sun1 1Department of Respiratory Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of China; 2Department of Oncology, The ...
Sun GY, Wang R, Xu R, Zeng DX, Zhou SJ, Xu X, Li M   +6 more
core  

Association of single nucleotide polymorphisms rs7164665, rs71461059, rs74765750, rs6762529 with sudden cardiac death

Российский кардиологический журнал, 2019
Aim. To confirm the association between sudden cardiac death (SCD) and single nucleotide polymorphisms rs7164665, rs71461059, rs74765750, rs6762529, identified in own genome-wide associative study as new molecular genetic markers of SCD.Material and ...
A. A. Ivanova, V. N. Maksimov, S. K. Malutina, V. P. Novoselov, M. I. Voevoda   +4 more
doaj   +1 more source

Self‐Assembled Calcite Architectures for Programmable Information Storage

Advanced Materials Technologies, EarlyView.
Programmable biomineralization enables the formation of 3D calcite architectures that encode information through spatially defined refractive‐index modulations. Data are written via laser‐directed mineralization, stored in stable voxelized mineral structures, and retrieved non‐destructively through optical diffraction, offering a pathway toward ultra ...
Congrui Jin, Yong Huang, Mehdi Ranjkesh Rashteh Roudi   +2 more
wiley   +1 more source

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

Advanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung, Victor Tsao, Alina D Peshkova, Oscar A. Marcos‐Contreras, Kim Ha, Brian M Dulmovits, Nkemdilim Okoli, Anvi Sinha, Gennadiy Fonar, Rong Qiu, Rolf D Bates, Janelle Yeboah, Carson Shalaby, Tyler Truex, Soomin Jeong, Edna C Hardeman, Peter W Gunning, Vladimir R Muzykantov, Jacob W Myerson, Christopher S Thom   +19 more
wiley   +1 more source

Patterns of nucleotide polymorphism distinguish temperate and tropical wild isolates of Caenorhabditis briggsae [PDF]

, 2006
Caenorhabditis briggsae provides a natural comparison species for the model nematode C. elegans, given their similar morphology, life history, and hermaphroditic mode of reproduction. Despite C.
Cutter, Asher, Cutter, Asher D., Felix, Marie-Anne, Barriere, Antoine, Charlesworth, Deborah   +4 more
core   +1 more source

Association of apolipoprotein E-219T>G promoter polymorphism with primary open angle glaucoma in Turkish population

International Journal of Ophthalmology, 2014
AIM: To investigate the association between apolipoprotein E (APOE) -219 T>G promoter polymorphism and primary open angle glaucoma (POAG).METHODS: Patients and healthy subjects were genotyped with polymerase chain reaction-restriction fragment length ...
Emel Saglar, Banu Bozkurt, Murat Irkec
doaj   +1 more source

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

Advanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang, Jiadong Yu, Guolin Li, Ya Li, Fanlian Zeng, Jing Hu, Yifan Zhou, Chengcheng Yue, Qixiang Zhao, Chen Zhang, Hong Zhou, Fulei Zhao, Yawen Hu, Pei Zhou, Linna Gu, Yuting Feng, Mingxiang He, Shishi Huang, Xiaochi Sun, Xinmeng Wang, Jie Tang, Xinyu Zeng, Wenling Wu, Nongyu Huang, Xinai Cui, Kaijun Cui, Jiong Li   +26 more
wiley   +1 more source

Single nucleotide polymorphism statistics (freq – frequency, Syn – synonymous). [PDF]

, 2013
Single nucleotide polymorphism statistics (freq – frequency, Syn – synonymous).
Anthony F. Barbet (324450), Anna M. Lundgren (324447), Michael J. Dark (324444)   +2 more
core   +1 more source

Human Brain Single Nucleotide Polymorphism: Validation of DNA Sequencing

Journal of Alzheimer's Disease Reports, 2018
Genetic factors may be involved in the onset of neurodegenerative diseases like Alzheimer’s disease. In the case of the familial type, the disease is due to an inherited mutation at specific sites in three genes. Also, there are some genetic risk factors
Ángel J. Picher, Félix Hernández, Bettina Budeus, Eduardo Soriano, Jesús Avila   +4 more
doaj   +1 more source

Human‐Centered Innovation: Precision Nutrition and the Future of Food

Advanced Science, EarlyView.
ABSTRACT Nutritional science is moving beyond one‐size‐fits‐all recommendations toward more precise and personalized approaches, yet its implementation pathway remains unclear. This paper proposes a human‐centered precision nutrition framework that highlights the central roles of artificial intelligence (AI), food innovation, and human agency.
Shanshan Zhang, Yonggan Sun, Jiaqi Jiang, Shaoping Nie   +3 more
wiley   +1 more source