Results 171 to 180 of about 260,303 (252)

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

Machine learning and multi-omic analysis reveal contrasting recombination landscape of A and C subgenomes of winter oilseed rape. [PDF]

Plant Genome
Montero-Tena JA, Zanini SF, Yildiz G, Kox T, Abbadi A, Snowdon RJ, Golicz AA.   +6 more
europepmc   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

Journal of Applied Toxicology, EarlyView.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz, Bayram Göktaş, İlker Ateş, Mustafa Çelik   +3 more
wiley   +1 more source

Analysis of copy number variations and candidate genes in recurrent pregnancy loss. [PDF]

PeerJ
Wang L, Yang L, Li S, Liu X, Tang P.
europepmc   +1 more source

Exploring the Relationship Between MDM4 Gene Polymorphisms (rs1380576 and rs4245739) and Breast Cancer Susceptibility in Bangladesh: A Case–Control Study

Journal of Clinical Laboratory Analysis, EarlyView.
Our findings indicated that the rs4245739 A>C polymorphism was not associated with BC risk in the Bangladeshi population, whereas the rs1380576 C>G polymorphism was significantly associated with BC risk. This study provides new insights into the genetic factors influencing breast cancer susceptibility in the Bangladeshi population, highlighting the ...
J. M. Aousiful Islam, Sharif Ahamed, Shafiqul Islam, M. Mahboob Hossain, Md Sadbean Hossain, Md. Shaki Mostaid, Md. Rabiul Islam, Md. Aminul Haque   +7 more
wiley   +1 more source

Young adult self‐harm: The role of victimisation and polygenic risk in a population‐based longitudinal study

JCPP Advances, EarlyView.
Abstract Background Victimisation has been associated with self‐harm (with or without suicidal intent), but little is known about this association during young adulthood—a distinct developmental period. Further, not all individuals who experience victimisation will later engage in self‐harm, suggesting the influence of other factors.
Filip Marzecki, Isabelle Ouellet‐Morin, Helena M. S. Zavos, Sylvana Côté, Richard E. Tremblay, Jean‐Philippe Gouin, Massimiliano Orri, Michel Boivin, Marie‐Claude Geoffroy   +8 more
wiley   +1 more source

Mendelian randomization analysis: causal link between hyperthyroidism/thyrotoxicosis and ovarian cancer. [PDF]

Discov Oncol
Wang H, Liang C, Yu Y, Lin J, Dong Y, Hong X, Huang H.   +6 more
europepmc   +1 more source

Unpacking early risks for peer victimization: A network analysis of early temperament and polygenic risk scores

JCPP Advances, EarlyView.
Abstract Background Children who show difficult temperament are at risk of peer victimisation, which in turn associates with numerous negative outcomes later in life. We used network analysis to examine whether specific aspects of difficult temperament contributed to these associations, and whether the links were moderated by variations in genetic ...
Tom C.‐H. Wu, Deniz Konac, Liliana Garcia‐Mondragon, Alex F. Martin, Barbara Maughan, Ted Barker   +5 more
wiley   +1 more source

Association of 25-hydroxyvitamin D levels and vitamin D receptor gene polymorphisms with breast cancer risk in Bangladeshi women. [PDF]

Sci Rep
Akter R, Islam MS, Mosaddek ASM, Akhtar MW, Afrose A, Haque MA, Azam F, Sharmin S, Hasan R, Hossain MM, Bhowmick RK, Asaduzzaman M.   +11 more
europepmc   +1 more source

PERCC1‐associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide

JPGN Reports, EarlyView.
Abstract Congenital diarrheas and enteropathies (CODE) are rare inherited disorders characterized by early‐onset intractable diarrhea. Though progress has been made in elucidating the genetic basis of CODE, much remains to be discovered. Another challenge is the lack of curative therapies—treatment is primarily supportive including enteral and ...
Angela Tran, Vivien Nguyen, Phuong Huynh
wiley   +1 more source