Results 171 to 180 of about 454,115 (308)

Effect of time to start of biologic therapy on treatment response in childhood arthritis: Results from the UCAN CAN‐DU study

Arthritis &Rheumatology, Accepted Article.
Objective To estimate the effect of time from symptom onset to start of biologic treatment on achieving inactive arthritis within six months in a cohort of juvenile idiopathic arthritis (JIA) patients. Methods The international UCAN CAN‐DU study prospectively enrolls JIA patients across Canada and the Netherlands.
Jelleke B. de Jonge, Sytze de Roock, Dieneke Schonenberg‐Meinema, J. Merlijn van den Berg, Deborah A. Marshall, Sebastiaan J. Vastert, Rae S.M. Yeung, Joost F. Swart, Susanne M. Benseler, The UCAN CAN‐DU and UCAN CURE consortia, Adam Huber, Alan Rosenberg, Alexander Mosoiu, Alisa Rachlis, Amy Xu, Andrea Human, Annet van Royen‐Kerkhof, Arthur Cheng, Berent Prakken, Bianca Lang, Brenleigh Jebb, Brian Feldman, Bruno Pereira, Chelsea DeCoste, Ciarán Duffy, Claire LeBlanc, Clare Hutchinson, Daniah Basodan, Danielle Brinkman, David Cabral, Dax G. Rumsey, Deborah Levy, Dilan Dissanayake, Elizabeth Legger, Elizabeth Stringer, Elizaveta Limenis, Ellen Schatorje, Elodie Boudes, Erika Van Nieuwenhove, Erkan Demirkaya, Esther Hoppenreijs, Evelyn Rozenblyum, Gaëlle Chédeville, Gillian Currie, Giske Biesbroek, Gordon Soon, Harper Cheng, Heinrike Schmeling, Herman Tam, Hon Yan Ng, Jaime Guzman, Jeanine McColl, Jennifer Ji Young Lee, Jonathan Park, Joseph Cafazzo, Kate Neufeld, Kim Morishita, Kristin Houghton, Liane Heale, Lillian Lim, Lily Lim, Lori Tucker, Lynn Spiegel, Maarten IJzerman, Marc Jansen, Mariken Gruppen, Marinka Twilt, Marleen Verkaaik, Mehul Jariwala, Mercedes Chan, Michelle Batthish, Michelle Kip, Muhammed Dhalla, Nadia Luca, Nickolas Blanchette, Nico Wulffraat, Nicole Johnson, Paivi Miettunen, Paul Dancey, Petra Hissink Muller, Philomine van Pelt, Piya Lahiry, Ravneet Sran, Rayfel Schneider, Rebeka Stevenson, Regina de Geus, Roberta Berard, Roman Jurencak, Ronald Laxer, Rosie Scuccimarri, Ross Petty, Ruud Verstegen, Sarah Campillo, Shirley Tse, Suzanne Ramsey, Sylvia Kamphuis, Tala El Tal, Tania Cellucci, Tara McGrath, Tommy Gerschman, Trang Duong, Tristan Kerr, Wineke Armbrust   +102 more
wiley   +1 more source

Relationship between NAFLD and coronary artery disease: A Mendelian randomization study

Hepatology, EarlyView., 2022
Abstract Background and Aims There is an ongoing debate on whether NAFLD is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the present study was to assess the causal relationship between NAFLD and CAD.
Zhewen Ren, Pomme I. H. G. Simons, Anke Wesselius, Coen D. A. Stehouwer, Martijn C. G. J. Brouwers   +4 more
wiley   +1 more source

GENE EXPRESSION AND SINGLE NUCLEOTIDE POLYMORPHISM (rs1140713) OF MICRORNA-126

The Iraqi Journal of Agricultural science
MicroRNAs are non-coding gene regulators that may serve as systemic lupus erythematosus biomarkers for diagnosis or prognosis. This study was aimed to identify the single nucleotide polymorphism (rs1140713) of microRNA-126 and its expression by using ...
W. L. Abdullah, R. M. Abed
doaj  

Advanced glycation end-product receptor gene (RAGE) polymorphisms in patients with acute coronary syndrome - a case-control study in the Polish population. [PDF]

BMC Med Genomics
Gutowska K, Ambroziak M, Podraza J, Puzianowska-Kuźnicka M, Czajkowski K, Budaj A, Kuryłowicz A.   +6 more
europepmc   +1 more source

HLA‐DQA1*01:02 is associated with antibody multi‐reactivity with citrulline‐containing type II collagen epitopes while HLA‐DRB1*04:01 is associated with more private antibody reactivity with citrulline‐containing IgG epitopes in rheumatoid arthritis

Arthritis &Rheumatology, Accepted Article.
Objective Anti‐citrullinated protein antibodies (ACPAs) in rheumatoid arthritis (RA) can be promiscuous, with cross‐reactive binding to many antigens containing short motifs, or private with little cross‐reactivity. Also, ACPA reactivity patterns differ among RA patients, including for motif‐containing epitopes in important self‐antigens like collagen ...
S. Janna Bashar, Courtney B. Myhr, Adam H. Titi, Zihao Zheng, Miriam A. Shelef   +4 more
wiley   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

The Role of Gut Microbiota on Idiopathic Pulmonary Fibrosis Mediated by Circulating Inflammatory Proteins: A Two-Step, Two-Sample Mendelian Randomization Study. [PDF]

Clin Respir J
Zhu H, Chen C, Guo H, Zhang B, Hu Q.
europepmc   +1 more source

Lamivudine and tenofovir pharmacokinetic variability in people with HIV in Papua New Guinea

British Journal of Clinical Pharmacology, EarlyView.
Aims Demographics and kidney function contribute to variability in lamivudine and tenofovir drug concentrations. The aim was to assess, for the first time, the pharmacokinetic variability of lamivudine and tenofovir in Papua New Guinean (PNG) HIV/AIDS patients.
Natália Bordin Andriguetti, Daniel Thomas Barratt, Joseph Tucci, Paul Pumuye, Andrew Alexander Somogyi   +4 more
wiley   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

Association of Gene Polymorphism of Matrix Metalloproteinase-9 With Chronic Periodontitis: A Cross-Sectional Survey in a South Indian Population. [PDF]

Cureus
Mohamed SC, Beevi N R, Banerjee M, Sathyan S, Nayar BR, Janam P.   +5 more
europepmc   +1 more source