Results 11 to 20 of about 444,739 (309)
Detection of Single-Nucleotide Polymorphism
BioTechniques, 1998 Weikuan Gu +2 more
doaj +4 more sources
Construction and analysis of single nucleotide polymorphism-single nucleotide polymorphism interaction networks. [PDF]
IET Syst Biol, 2013 The study of gene regulatory network and protein–protein interaction network is believed to be fundamental to the understanding of molecular processes and functions in systems biology. In this study, the authors are interested in single nucleotide polymorphism (SNP) level and construct SNP–SNP interaction network to understand genetic characters and ...
Liu Y, Li X, Liu Z, Chen L, Ng MK.
europepmc +5 more sources
Single-Nucleotide Polymorphisms in Soybean [PDF]
Genetics, 2003 Abstract Single-nucleotide polymorphisms (SNPs) provide an abundant source of DNA polymorphisms in a number of eukaryotic species. Information on the frequency, nature, and distribution of SNPs in plant genomes is limited. Thus, our objectives were (1) to determine SNP frequency in coding and noncoding soybean (Glycine max L.
Perry B. Cregan +12 more
openaire +3 more sources
Detection of Single Nucleotide Polymorphisms [PDF]
Current Issues in Molecular Biology, 2003 Single nucleotide polymorphism (SNP) detection technologies are used to scan for new polymorphisms and to determine the allele(s) of a known polymorphism in target sequences. SNP detection technologies have evolved from labor intensive, time consuming, and expensive processes to some of the most highly automated, efficient, and relatively inexpensive ...
Kwok, Pui-Yan, Chen, Xiangning
openaire +3 more sources
Investigations into the molecular effects of single nucleotide polymorphism [PDF]
, 2000 Objectives: DNA sequences are very rich in short repeats and their pattern can be altered by point mutations. We wanted to investigate the effect of single nucleotide polymorphism (SNP) on the pattern of short DNA repeats and its biological consequences.
Lohrer, Horst D., Tangen, Uwe
core +1 more source
The C242T polymorphism of the NAD(P)H oxidase p22(phox) subunit is associated with an enhanced risk for cerebrovascular disease at a young age [PDF]
, 2008 Background and Purpose: Oxidative stress has been proposed as a major contributing factor for vascular disease, that acts independently from its participation in predisposing disorders such as diabetes and arterial hypertension.
Genius, Just +2 more
core +1 more source
Revista Brasileira de Hematologia e Hemoterapia, 2015 Objective: To standardize the single nucleotide polymorphism array (SNPa) method in acute myeloid leukemia/myelodysplastic syndromes, and to identify the similarities and differ- ences between the results of this method and karyotyping.
Thiago Rodrigo de Noronha +2 more
doaj +1 more source
Bulk segregant analysis using single nucleotide polymorphism microarrays. [PDF]
PLoS ONE, 2011 Bulk segregant analysis (BSA) using microarrays, and extreme array mapping (XAM) have recently been used to rapidly identify genomic regions associated with phenotypes in multiple species.
Anthony Becker +4 more
doaj +1 more source
A novel DRD2 single-nucleotide polymorphism associated with schizophrenia predicts age of onset: HapMap tag-sincle-nucleotide polymorphism analysis [PDF]
, 2012 Background: Dopamine D2 receptor (DRD2) is thought to be critical in regulating the dopaminergic pathway in the brain which is known to be important in the aetiology of schizophrenia. It is therefore not surprising that most antipsychotic medication acts
Hughes, Ian +5 more
core +2 more sources
Haematologica, 2012 Background The recent advent of genome-wide molecular platforms has facilitated our understanding of the human genome and disease, particularly copy number aberrations.
Hee-Jin Kim +10 more
doaj +1 more source