Results 31 to 40 of about 306,247 (295)

H5N1 Clade 2.2 Polymorphism Tracing Identifies Influenza Recombination and Potential Vaccine Targets [PDF]

, 2007
Highly pathogenic Influenza A H5N1 was first identified in Guangdong Province in 1996, followed by human cases in Hong Kong in 1997 1. The number of confirmed human cases now exceeds 300 and the associated Case Fatality Rate exceeds 60% 2.
Nasr M. ElSayed, A Nayei, A A. Abdelghani, Jeffery Tjaden, Mona Aly, Marshall Monteville, Hala Essmat, A Abdelghani, Bruce Boynton, A I. Nayei, Henry Niman, Moustafa Mansour, Kenneth Earhart, Henry L. Niman, Magdi Saad, Moustafa M. Mansour, Hala M. Essmat, Mona M. Aly, Nasr ElSayed, Magdi D. Saad, A-SA Arafa, Kenneth C. Earhart, Elassai Labib, Bruce R. Boynton, E Ayoub, Marshall R. Monteville, Elassai M. Labib   +26 more
core   +2 more sources

Superoxide dismutase coding of gene polymorphisms associated with susceptibility to Parkinson’s disease [PDF]

Journal of Integrative Neuroscience, 2019
Oxidative stress linked to the etiology of Parkinson’s disease, which is characterized by chronic and progressive neurodegeneration of dopamine neurons.
Chunlei Liu, Jinju Fang, Wenke Liu
doaj   +1 more source

Single-nucleotide polymorphism (SNP) markers associated with cassava starch pasting properties based on the MLM, MLMM, and FarmCPU methods. [PDF]

, 2022
Single-nucleotide polymorphism (SNP) markers associated with cassava starch pasting properties based on the MLM, MLMM, and FarmCPU methods.
Carlos Wanderlei Piler Carvalho (5695028), Luciana Alves de Oliveira (11985977), Eder Jorge de Oliveira (8544567), Ana Carla Brito (6515063), Massaine Bandeira Sousa (11985974), Cristiano Silva dos Santos (11985971)   +5 more
core   +1 more source

ABL single nucleotide polymorphisms may masquerade as BCR-ABL mutations associated with resistance to tyrosine kinase inhibitors in patients with chronic myeloid leukemia

Haematologica, 2008
The BCR-ABL K247R change is based on a rare single nucleotide polymorphism occurring likewise in healthy controls and non-hematologic cell types. Despite its juxtaposition to the P-loop, functional analysis showed no alteration compared to non-mutated ...
Thomas Ernst, Jana Hoffmann, Philipp Erben, Benjamin Hanfstein, Armin Leitner, Rüdiger Hehlmann, Andreas Hochhaus, Martin C. Müller   +7 more
doaj   +1 more source

Programmed death-ligand 1 single nucleotide polymorphism affects breast cancer chemosensitivity and adverse events in the neoadjuvant setting

The International Journal of Biological Markers, 2020
Objective We aimed to determine whether single nucleotide polymorphisms in the PD-L1 gene are related to the response and adverse events of patients receiving neoadjuvant therapy and to explore the mechanism.
Jinglu Lu*, Ziping Wu*, Jing Peng, Shuguang Xu, Liheng Zhou, Yanping Lin, Yan Wang, Wenjin Yin, Jinsong Lu   +8 more
doaj   +1 more source

Inflammasome genetic variants are associated with tuberculosis, HIV-1 infection, and TB/HIV-immune reconstitution inflammatory syndrome outcomes

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundTuberculosis (TB) and AIDS are the leading causes of infectious diseases death worldwide. Here, we investigated the relationship between from single nucleotide polymorphisms (SNPs) of the NLRP3, CARD8, AIM2, CASP-1, IFI16, and IL-1β ...
Nathalia Beatriz Ramos de Sá, Nara Cristina Silva de Souza, Milena Neira-Goulart, Marcelo Ribeiro-Alves, Tatiana Pereira Da Silva, Jose Henrique Pilotto, Jose Henrique Pilotto, Valeria Cavalcanti Rolla, Carmem B. W. Giacoia-Gripp, Luzia Maria de Oliveira Pinto, Daniel Scott-Algara, Mariza Gonçalves Morgado, Sylvia Lopes Maia Teixeira   +12 more
doaj   +1 more source

Inferring the demographic history and rate of adaptive substitution in Drosophila [PDF]

, 2006
An important goal of population genetics is to determine the forces that have shaped the pattern of genetic variation in natural populations. We developed a maximum likelihood method that allows us to infer demographic changes and detect recent positive ...
Stephan Wolfgang, Li, Haipeng, Stephan, Wolfgang, Wolfgang Stephan, Li Haipeng, Haipeng Li   +5 more
core   +1 more source

Single Nucleotide Polymorphism (SNP) identified.xlsx [PDF]

, 2019
Single Nucleotide Polymorphism (SNP ...
RODRIGO VIDAL (6845669)
core   +1 more source

Inter-individual variation in nucleotide excision repair in young adults: effects of age, adiposity, micronutrient supplementation and genotype [PDF]

, 2009
Nucleotide excision repair (NER) is responsible for repairing bulky helix-distorting DNA lesions and is essential for the maintenance of genomic integrity.
Mathers, John, Williams, Elizabeth, Daly, Ann, Tyson, John, Caple, Fiona, Hesketh, John, Spiers, Alison   +6 more
core   +1 more source

Investigations into the molecular effects of single nucleotide polymorphism [PDF]

, 2000
Objectives: DNA sequences are very rich in short repeats and their pattern can be altered by point mutations. We wanted to investigate the effect of single nucleotide polymorphism (SNP) on the pattern of short DNA repeats and its biological consequences.
Lohrer, Horst D., Tangen, Uwe
core   +1 more source