Results 91 to 100 of about 1,178,111 (366)

Variation in the Untranslated Genome and Susceptibility to Infections

Frontiers in Immunology, 2018
The clinical outcomes of infections are highly variable among individuals and are determined by complex host-pathogen interactions. Genome-wide association studies (GWAS) are powerful tools to unravel common genetic variations that are associated with ...
Veron Ramsuran, Rodger Ewy, Hoang Nguyen, Smita Kulkarni   +3 more
doaj   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Combining Inclusion Polymorphism and Parametric Polymorphism [PDF]

arXiv, 1999
We show that the question whether a term is typable is decidable for type systems combining inclusion polymorphism with parametric polymorphism provided the type constructors are at most unary. To prove this result we first reduce the typability problem to the problem of solving a system of type inequations.
arxiv  

Variation in Enamel Formation Genes Influences Enamel Demineralization In Vitro in a Streptococcus mutans Biofilm Model

Frontiers in Physiology, 2017
Genetic studies have shown that variations in enamel formation genes are associated with caries susceptibility. The aim of this study was to test in vitro whether variants in these genes are associated with dental enamel demineralization in a ...
Liangyue Pang, Liangyue Pang, Qinghui Zhi, Qinghui Zhi, Peilin Zhuang, Peilin Zhuang, Lixia Yu, Lixia Yu, Ye Tao, Ye Tao, Huancai Lin, Huancai Lin   +11 more
doaj   +1 more source

Switching From Acceptor to FRET Donor: How the Organic Solar Cell Architecture Can Change the Role of a Chromophore

Advanced Functional Materials, EarlyView.
The non‐fullerene acceptor o‐IDT‐BT‐DCV is used in both binary and ternary blends to investigate the role that it plays in each device architecture. The charge generation pathways are found to differ between the binary and ternary blends with o‐IDT‐BT‐DCV becoming a second donor in the ternary blend.
Hui Jin, Neil Mallo, Guanran Zhang, Oliver Lindsay, Ronan Chu, Mile Gao, Shaun McAnally, Isaac M. Etchells, Paul L. Burn, Ian R. Gentle, Paul E. Shaw   +10 more
wiley   +1 more source

Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism.

Biochemical Journal, 1994
In humans, glutathione-dependent conjugation of halomethanes is polymorphic, with 60% of the population classed as conjugators and 40% as non-conjugators. We report the characterization of the genetic polymorphism causing the phenotypic difference.
S. Pemble, K. R. Schroeder, S. R. Spencer, David J. Meyer, E. Hallier, Hermann M. Bolt, B. Ketterer, J. B. Taylor   +7 more
semanticscholar   +1 more source

Effect of childhood trauma on adult depression and neuroendocrine function: sex-specific moderation by CRH receptor 1 gene

Frontiers in Behavioral Neuroscience, 2009
Variations of the corticotropin-releasing hormone receptor 1 (CRHR1) gene appear to moderate the development of depression after childhood trauma. Depression more frequently affects women than men.
Christine Heim, Bekh Bradley, Bekh Bradley, Tanja Mletzko, Todd C Deveau, Dominique L Musselmann, Charles B Nemeroff, Kerry J Ressler, Kerry J Ressler, Elisabeth B Binder, Elisabeth B Binder, Elisabeth B Binder   +11 more
doaj   +1 more source

Butterfly‐Inspired Hierarchical Hybrid Composites for Lightweight Structural Thermal Management Applications

Advanced Functional Materials, EarlyView.
Emulating nature's unparalleled engineering, this work introduces butterfly‐inspired hybrid composites for high‐performance transportation and defense sectors. Leveraging biomimicry, these lightweight composites feature butterfly leg‐inspired hierarchical fibrous assemblies and butterfly wing‐inspired sandwich‐structured architecture, to achieve ...
Nello D. Sansone, Rafaela Aguiar, Mahmoud Embabi, Nichole Cheung, Anthony V. Tuccitto, Nathan R. S. Chang, Matthew Leroux, Patrick C. Lee   +7 more
wiley   +1 more source

Apolipoprotein E polymorphism and atherosclerosis.

Arteriosclerosis, 1988
The apo E locus contributes to determining the variation in plasma cholesterol levels of healthy and diseased populations. It also influences the expression of hyperlipidemia and appears to modulate the susceptibility to atherosclerosis in a complex ...
J. Davignon, R. Gregg, C. Sing
semanticscholar   +1 more source

A Close Look at the Local Structure of Functional Polymers: The Example of Poly(Vinylidene Fluoride)

Advanced Functional Materials, EarlyView.
To accurately develop structure‐property relationships in functional macromolecules, it is increasingly important to consider the local chain arrangement in addition to long‐range order. It is demonstrated in the case of poly(vinylidene fluoride) that solid‐state nuclear magnetic resonance (NMR) spectroscopy can provide detailed insights into the local
Henry J. Kantrow, Claire Welton, Neethu Thomas, Vincent Sarou‐Kanian, Tomasz Pawlak, Natalie Stingelin, G. N. Manjunatha Reddy   +6 more
wiley   +1 more source