Results 11 to 20 of about 432,582 (269)
Comparison of the Genetic Alterations between Primary Colorectal Cancers and Their Corresponding Patient-Derived Xenograft Tissues [PDF]
Genomics & Informatics, 2018 Patient-derived xenograft (PDX) models are useful tools for tumor biology research and testing the efficacy of candidate anticancer drugs targeting the druggable mutations identified in tumor tissue.
Sang Mi Yu +2 more
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Frontiers in Genetics, 2022 Background: To decipher mutational signatures and their associations with biological implications in cutaneous melanomas (CMs), including those with a low ultraviolet (UV) signature.Materials and Methods: We applied non-negative matrix factorization (NMF)
Yoon-Seob Kim +7 more
doaj +1 more source
A Variant in Is Associated with the Risk of Ankylosing Spondylitis in Koreans [PDF]
Genomics & Informatics, 2017 Ankylosing spondylitis (AS) is a chronic autoinflammatory disease that affects the spine and sacroiliac joints. Regarding its etiology, although HLA-B27 is known to be the strongest genetic factor of AS, much evidence suggests the potential contribution ...
Sung-Min Cho +2 more
doaj +1 more source
PolyMorph: A P300 Polymorphic Speller [PDF]
, 2013 P300 is an electric signal emitted by brain about 300 milliseconds after a rare, but relevant-for-the-user event. Even if it is hard to identify and it provides a low-rate communication channel, it can be used in cases in which other evoked potentials fail.
CASAGRANDE, ALBERTO +4 more
openaire +3 more sources
Validation of Customized Cancer Panel for Detecting Somatic Mutations and Copy Number Alterations [PDF]
Genomics & Informatics, 2017 Accurate detection of genomic alterations, especially druggable hotspot mutations in tumors, has become an essential part of precision medicine.
Su-Hye Choi +2 more
doaj +1 more source
Journal of Advanced Pharmaceutical Technology & Research, 2023 Genetic variation remains a topic of great interest due to its potential as a risk factor for various diseases. Interactions between genes contribute to diverse phenotypes in response to factors such as infection.
Darnifayanti Darnifayanti +3 more
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Global Medical Genetics, 2023 A coronavirus disease 2019 (COVID-19) disease, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has created significant concern since December 2019 worldwide. The virus is known to be highly transmissible.
Begimai Mamurova +9 more
doaj +1 more source
BMC Medical Genetics, 2020 Background Dedifferentiated liposarcoma (DDLPS), which accounts for an estimated 15–20% of liposarcomas, is a high-grade and aggressive malignant neoplasm, exhibiting a poor response to available therapeutic agents.
Yoon-Seob Kim +3 more
doaj +1 more source
Life, 2023 Tissue inhibitor of metalloproteinase-2 (TIMP-2) is an endogenous inhibitor of matrix metalloproteinase-2 and is highly expressed in breast cancer (BC) cases at diagnosis.
Yun-Chi Wang +11 more
doaj +1 more source
Angewandte Chemie, 2005 (Figure Presented) At long last, the crystal structure of the metastable form of benzamide, whose existence has been known of for over 170 years, has finally been solved by using a combination of in situ crystallization, high-speed synchrotron X-ray powder diffraction, and global-optimization methods of structure determination (see picture).
W. I. F. David +5 more
openaire +4 more sources