Results 81 to 90 of about 727,358 (304)
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy+14 more
wiley +1 more source
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma+3 more
wiley +1 more source
Palm oil (PO) and palm kernel oil (PKO) compositions (100/0, 80/20, 60/40, 50/50, 40/60, 20/80 and 0/100) were interesterified in laboratory scale under predetermined conditions (0.4% sodium metoxide, 20 minutes, 100ºC).
Renato Grimaldi+3 more
doaj +1 more source
Multilocus patterns of nucleotide variability and the demographic and selection history of drosophila melanogaster populations [PDF]
Uncertainty about the demographic history of populations can hamper genome-wide scans for selection based on population genetic models. To obtain a portrait of the effects of demographic history on genome variability patterns in Drosophila melanogaster ...
Andolfatto, Peter+3 more
core +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik+2 more
wiley +1 more source
Second order conservative languages with a Maltsev polymorphism also have a majority polymorphism [PDF]
The paper proves that for any second order conservative constraint language with a Maltsev polymorphism there is a majority polymorphism. Moreover, the majority polymorphism can be defined by the Maltsev polymorphism.
arxiv
Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet+6 more
wiley +1 more source
Association study between the MDR1 gene and clinical characteristics in schizophrenia
Objective: Schizophrenia is a complex psychiatric disorder, characterized by disturbed patterns of thought and affecting 0.3-2.0% of the world population.
Carlos A. Tovilla-Zárate+8 more
doaj +1 more source
In this paper we consider a special class of polymorphisms with invariant measure, - (cf.[1])- the algebraic polymorphisms of compact groups. A general polymorphism is -- by definition -- a many-valued map with invariant measure, and the conjugate operator of a polymorphism is a Markov operator (i.e., a positive operator on $L^2$ of norm 1 which ...
arxiv
Development of SSR markers from Citrus clementina (Rutaceae) BAC end sequences and interspecific transferability In Citrus (P148) [PDF]
Microsatellite primers were developed from bacterial artificial chromosome (BAC) end sequences (BES) of Citrus clementina and their transferability and polymorphism tested in the genus Citrus for future anchorage of physical and genetic maps and ...
Navarro, Luis+5 more
core