Results 81 to 90 of about 837,662 (281)

Development and External Validation of a Genetic Risk Score for Pain in Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Several single‐nucleotide polymorphisms (SNPs) have been associated with chronic pain syndromes. Our objective was to determine whether genetic variants are associated with pain and disease activity in rheumatoid arthritis (RA). Methods Participants were included from two independent RA cohorts: FORWARD (National Databank for Rheumatic ...
Katie J. McMenamin, Thomas R. Riley IV, Kristin Wipfler, Kaleb Michaud, Austin Wheeler, Bryant R. England, Brian Sauer, Katherine D. Wysham, Rui Xiao, Michael March, Grant W. Cannon, Sylvanus Toikumo, Henry R. Kranzler, Rachel L. Kember, Ted R. Mikuls, Joshua F. Baker   +15 more
wiley   +1 more source

Replicators in Fine-grained Environment: Adaptation and Polymorphism

, 2009
Selection in a time-periodic environment is modeled via the two-player replicator dynamics. For sufficiently fast environmental changes, this is reduced to a multi-player replicator dynamics in a constant environment.
Armen E. Allahverdyan, Chin-Kun Hu, E. Dempster, J. Hofbauer, J. H. Gillespie, J. L. Cornette, L. A. Bach, L. D. Landau, R. Levins, V. Grant, Yu. M. Svirezhev   +10 more
core   +1 more source

Response to allopurinol and febuxostat according to the fractional excretion of urate in men with gout

Arthritis Care &Research, Accepted Article.
Background Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of urate (FEUA) also modulates this response and relates to oxypurinol concentrations. We further evaluated its potential influence
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source

Exploring crystal structure–physical property relationships with pressure

IUCrJ
From its conception, X-ray crystallography has provided a unique understanding of the structure, bonding and electronic state of materials, which, in turn, unlocks a means of examining the properties and function of crystalline systems.
David R. Allan
doaj   +1 more source

Association between MTHFR C677T polymorphism and non-traumatic osteonecrosis of the femoral head: An update meta-analysis

Pteridines, 2020
Objective To investigate the correlation between MTHFR C677T polymorphism and non-traumatic osteonecrosis of the femoral head.
Zhang Tao, Ye Shanshan, Chen Zhenzhong, Ma Yunmiao   +3 more
doaj   +1 more source

Polymorphism and apartness.

Notre Dame Journal of Formal Logic, 1991
The author gives a new intuitionistic model \({\mathcal C}\) for the second- order polymorphic lambda calculus. \({\mathcal C}\) is a proper subcategory of the category \({\mathcal M}\) of realizability-valued modest sets on which earlier intuitionistic models have been constructed.
openaire   +3 more sources

Polymorphism of cephaloridine

Journal of Pharmacy and Pharmacology, 1968
Abstract Infrared spectra of Nujol mulls and X-ray powder photographs have shown that cephaloridine can exist in at least six different crystalline forms. The preparation, interconversion and properties of these forms are discussed. Proton magnetic resonance spectroscopy has been used to check their chemical identity.
J H, Chapman, J E, Page, A C, Parker, D, Rogers, C J, Sharp, S E, Staniforth   +5 more
openaire   +2 more sources

Validation of a Genetic Risk Score Combined with Clinical Variables for Predicting Pulmonary Fibrosis in early Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Objectives Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). The study aimed to externally validate a genetic risk score (GRS) and a combined risk score for predicting the risk of RA‐associated PF in an independent cohort of early‐RA patients. Methods This study utilized an inception cohort of 1118 patients
Mikael Brink, Austin Wheeler, Bryant R. England, Solbritt Rantapää‐Dahlqvist   +3 more
wiley   +1 more source

Talent inclusion: An imperfect solution to genetic testing in sport - Response to commentaries

Current Issues in Sport Science
We are extremely grateful our esteemed colleagues Craig Pickering, Duarte Araújo, Keith Davids, and Kevin Till have read and offered insightful reflections on the target article “Talent inclusion and genetic testing in sport: A practitioner’s guide”. We
Alexander B. T. McAuley, Joseph Baker, Kathryn Johnston, Ian Varley, Adam J. Herbert, Bruce Suraci, David C. Hughes, Loukia G. Tsaprouni, Adam L. Kelly   +8 more
doaj   +1 more source

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source