Results 11 to 20 of about 751 (90)

Association between a C8orf13-BLK polymorphism and polymyositis/dermatomyositis in the Japanese population: an additive effect with STAT4 on disease susceptibility.

PLoS ONE, 2014
BackgroundAccumulating evidence has shown that several non-HLA genes are involved in the susceptibility to polymyositis/dermatomyositis. This study aimed to investigate the involvement of C8orf13-BLK, one of the strongest candidate genes for autoimmune ...
Tomoko Sugiura, Yasushi Kawaguchi, Kanako Goto, Yukiko Hayashi, Takahisa Gono, Takefumi Furuya, Ichizo Nishino, Hisashi Yamanaka   +7 more
doaj   +1 more source

Identification of Palmitoleic Acid Controlled by mTOR Signaling as a Biomarker of Polymyositis

Journal of Immunology Research, 2017
Polymyositis (PM) is a chronic disease characterized by muscle pain, weakness, and increase in muscle-related enzymes, accompanied with inflammations in lymphocytes.
Geng Yin, Ying Wang, Xiao-min Cen, Yuan Yang, Min Yang, Qi-bing Xie   +5 more
doaj   +1 more source

Roles of macrophage migration inhibitory factor in polymyositis: Inflammation and regeneration

Journal of International Medical Research, 2018
Objective To elucidate the clinical significance of macrophage migration inhibitory factor (MIF) serum concentration in patients with polymyositis. Methods Thirty-six patients with polymyositis were enrolled.
Yu-Qiong Zou, Wei-Dong Jin, Ya-Song Li
doaj   +1 more source

The clinical application of tumor markers in the screening of malignancies and interstitial lung disease of dermatomyositis/polymyositis patients: A retrospective study

SAGE Open Medicine, 2018
Objective: To examine the clinical utility of tumor markers in dermatomyositis/polymyositis patients in Taiwan. Method: Data were collected retrospectively from the database of Taichung Veterans General Hospital in Taiwan from 1998 to 2014.
Chong Hong Lim, Chih-Wei Tseng, Ching-Tsai Lin, Wen-Nan Huang, Yi-Hsing Chen, Yi-Ming Chen, Der-Yuan Chen   +6 more
doaj   +1 more source

Bilateral leg pain and unilateral calf atrophy caused by polymyositis accompanying lumbar spinal stenosis and disc herniation: a case report

Journal of International Medical Research, 2022
Polymyositis is a subgroup of idiopathic inflammatory myopathies characterized by symmetric proximal limb weakness and chronic skeletal muscle inflammation.
In-Hwa Baek, Hyung-Youl Park, Ho-Young Jung, Jun-Seok Lee   +3 more
doaj   +1 more source

Polymyositis following varicella and mumps infection in adults: report of two cases

Reumatismo, 2023
Idiopathic immune myopathies (IIMs) are autoimmune diseases caused by immune-mediated muscle damage. The etiology remains unclear. Epidemiological and experimental studies, both in animals and humans, hint at viruses as major environmental factors able ...
F. Masini, K. Gjeloshi, E. Pinotti, R. Ferrara, C. Romano, G. Cuomo   +5 more
doaj   +1 more source

Severe myopathy in a patient with chronic neurological disease – diagnostic challenges [PDF]

Romanian Journal of Rheumatology, 2023
Polymyositis is a rare disease that belongs to the idiopathic inflammatory myopathies (IIMs) group, characterized by chronic muscle inflammation, and in rare cases a life-threatening condition due to extra-muscular involvement.
Cristian-Mihai Ilie, Suzana Popescu, Sinziana Daia-Iliescu, Ioana Saulescu, Denisa Predeteanu, Violeta-Claudia Bojinca, Andra Balanescu, Daniela Opris-Belinski   +7 more
doaj   +1 more source

High-Dose Subcutaneous Immunoglobulins for the Treatment of Severe Treatment-Resistant Polymyositis

Case Reports in Rheumatology, 2014
Polymyositis is a rare debilitating condition characterized by chronic inflammation and muscle weakness. Standard treatments include corticosteroids and immunosuppressants; however, resistance to these regimens may develop.
Cherin Patrick, Delain Jean-Christophe, Crave Jean-Charles, Cartry Odile   +3 more
doaj   +1 more source

Chronic-graft-versus-host-disease-related polymyositis: a 17-months-old child with a rare and late complication of haematopoietic stem cell transplantation.

Mediterranean Journal of Hematology and Infectious Diseases, 2020
Background: Chronic graft versus host disease (cGVHD) occurs in 20-30% of paediatric patients receiving haemopoietic stem cell transplantation (HSCT). Neuromuscular disorders such as polymyositis are considered a rare and distinctive but non-diagnostic ...
Matteo Chinello, Rita Balter, Massimiliano De Bortoli, Virginia Vitale, Ada Zaccaron, Elisa Bonetti, Paola Tonin, Gaetano Vattemi, Valeria Guglielmi, Simone Cesaro   +9 more
doaj   +1 more source

Severe Rhabdomyolysis without Systemic Involvement: A Rare Case of Idiopathic Eosinophilic Polymyositis

Case Reports in Rheumatology, 2015
Introduction. Eosinophilic polymyositis (EPM) is a rare cause of rhabdomyolysis characterized by eosinophilic infiltrates in the muscle. We describe the case of a young patient with eosinophilic polymyositis causing isolated severe rhabdomyolysis without
Ayesha Farooq, Vivek Choksi, Andrew Chu, Dhruti Mankodi, Sameer Shaharyar, Keith O’Brien, Uday Shankar   +6 more
doaj   +1 more source