Results 41 to 50 of about 27,152 (204)

Circulating plasma microRNA profiling in patients with polymyositis/dermatomyositis before and after treatment: miRNA may be associated with polymyositis/dermatomyositis

Inflammation and Regeneration, 2018
MicroRNAs (miRNAs) are involved in the regulation of key biological processes and have been implicated in various diseases, including autoimmune disorders.
Takuya Hirai, K. Ikeda, H. Tsushima, M. Fujishiro, K. Hayakawa, Y. Yoshida, S. Morimoto, K. Yamaji, Y. Takasaki, K. Takamori, N. Tamura, I. Sekigawa   +11 more
semanticscholar   +1 more source

Acute rhabdomyolysis with severe polymyositis following ipilimumab-nivolumab treatment in a cancer patient with elevated anti-striated muscle antibody

Journal of Immunotherapy for Cancer, 2016
BackgroundImmune checkpoint inhibitors have revolutionized cancer therapy since these drugs target inhibitory pathways on T cells, which result in durable anti-tumor immune responses and significant overall survival for a subset of cancer patients. These
Mehmet A. Bilen, S. Subudhi, Jianjun Gao, N. Tannir, S. Tu, Padmanee Sharma   +5 more
semanticscholar   +1 more source

Systemic Autoimmune Rheumatic Disease Risk: Association With Long‐Term Exposure to Fine Particulate Matter

Arthritis &Rheumatology, EarlyView.
Objective Fine particulate matter (PM2.5) is a possible trigger of systemic autoimmune rheumatic diseases (SARDs). We investigated SARDs risk related to long‐term exposure to PM2.5 and its components (ammonium, black carbon, mineral dust, sea salt, nitrate, sulfate, organic matter), the composition of which may affect toxicity.
Mareva Geslin, Julien Vachon, Naizhuo Zhao, Elhadji Anassour Laouan Sidi, Sonia Jean, Audrey Smargiassi, Sasha Bernatsky   +6 more
wiley   +1 more source

Ultrastructural muscle and neuro-muscular junction alterations in polymyositis

Нервно-мышечные болезни, 2015
Ultrastructural analysis of 7 biopsies from m.palmaris longus and m.deltoideus in patients with confirmed polymyositis revealed alterationand degeneration of muscle fibers and anomalies of neuro-muscular junction (NMJ).
L. L. Babakova, O. M. Pozdnyakov
doaj   +1 more source

Alu Overexpression Leads to an Increased Double‐stranded RNA Signature in Dermatomyositis

Arthritis &Rheumatology, Accepted Article.
Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the non‐coding genome in disease pathogenesis.
Rayan Najjar, Andrew Mammen, Tomas Mustelin   +2 more
wiley   +1 more source

Idiopathic inflammatory myopathies: Contributions from India

Indian Journal of Rheumatology, 2020
A careful literature search would reveal significant contributions by Indian clinicians and basic researchers in the field of Idiopathic inflammatory myopathies (IIMs).
Anand Narayan Malaviya
doaj   +1 more source

National Mortality Databases to Assess Disease Burden in Systemic Autoimmune Diseases: A Valuable Resource, But with Limitations

Arthritis &Rheumatology, Accepted Article.
Disease‐specific mortality statistics are useful measures of disease burden. Population‐based studies from a few United States counties have reported mortality in systemic autoimmune diseases (SAID). However, due to substantial differences in the population structure of these counties as well as relatively small numbers of SAID deaths in these counties,
Ram Raj Singh
wiley   +1 more source

Polymyositis-Dermatomyositis and Interstitial Lung Disease in Pregnant Woman Successfully Treated with Cyclosporine and Tapered Steroid Therapy

Case Reports in Rheumatology, 2019
Polymyositis-dermatomyositis is extremely rare during pregnancy, and immunosuppressive therapy should be administered after carefully considering the effects on both the mother and fetus.
Saito Mayu, Sakiko Isojima, Yoko Miura, Shinichiro Nishimi, Mika Hatano, Takahiro Tokunaga, Ryo Takahashi, Keiko Koide, Yusuke Miwa   +8 more
doaj   +1 more source

Acute heart failure and rhabdomyolysis: a clue for the diagnosis of polymyositis with cardiac involvement

Reumatismo, 2017
Polymyositis is an idiopathic inflammatory myopathy, characterized by proximal muscle weakness and sometimes extramuscular manifestations. We report the case of a 51-year-old male, with history of complete heart block, which required pacemaker ...
P. Pinto-Lopes, L. Carneiro-Leão, R. Morais, J. Pinheiro, A. Vieira Lopes, P. Bettencourt   +5 more
doaj   +1 more source

Anti-SRP antibody-associated necrotizing myopathy: 2 clinical cases

Нервно-мышечные болезни, 2023
Necrotizing myopathies are a subtype of autoimmune myopathies characterized by muscle fiber necrosis with minimal infiltration by inflammatory cells on muscle biopsy. This group of myopathies is defined by flaccid palsies due to prima‑ ry skeletal muscle
F. A. Abbasov, G. V. Zemtsova, P. A. Popov, K. I. Chekhonatskaya, D. V. Kukhno, M. M. Severova, M. V. Shmyreva, A. A. Kindarova, D. Yu. Schekochikhin   +8 more
doaj   +1 more source