Results 211 to 220 of about 15,147 (259)
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Peptide Antibiotics (Polymyxin B and Polymyxin E)
1978Of the five polymyxins, A, B, C, D and E, originally isolated from a spore-bearing bacillus called variously B. aerosporus and B. polymyxa (Garrod et al., 1973), only two have found clinical usefulness, namely polymyxin B, usually in the form of the sulphate, and polymyxin E (colistin), either as the sulphate or sodium sulphomethate.
A. P. Ball, J. A. Gray, J. McM. Murdoch
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Battle of polymyxin induced nephrotoxicity: Polymyxin B versus colistin
International Journal of Antimicrobial AgentsNephrotoxicity is the most serious and common adverse effect that limits the use of polymyxins. This study compared polymyxin E (colistin) and polymyxin B regarding drug-related nephrotoxicity.This study was conducted as a retrospective cohort study in a university hospital between January 2020 and July 2022.
Fatma Nisa Ballı +8 more
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Biomedical Chromatography
AbstractTo facilitate clinical therapeutic drug monitoring (TDM) of polymyxin B (PB) and polymyxin E (PE), we developed and validated a simple LC–MS/MS method for simultaneous determination of PB (including polymyxin B1 (PB1), polymyxin B2 (PB2), polymyxin B3 (PB3) and isoleucine‐polymyxin B1 (ile‐PB1)) and PE (including polymyxin E1 (PE1) and ...
Feng Chen +6 more
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AbstractTo facilitate clinical therapeutic drug monitoring (TDM) of polymyxin B (PB) and polymyxin E (PE), we developed and validated a simple LC–MS/MS method for simultaneous determination of PB (including polymyxin B1 (PB1), polymyxin B2 (PB2), polymyxin B3 (PB3) and isoleucine‐polymyxin B1 (ile‐PB1)) and PE (including polymyxin E1 (PE1) and ...
Feng Chen +6 more
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Rescuing the Last-Line Polymyxins: Achievements and Challenges
Pharmacological Reviews, 2021Tony Velkov, Qi Zhou, Jian Li
exaly