Results 1 to 10 of about 85,546 (259)

Lumos for the long trail: Strategies for clinical diagnosis and severity staging for diabetic polyneuropathy and future directions

Journal of Diabetes Investigation, 2020
Diabetic polyneuropathy, which is a chronic symmetrical length‐dependent sensorimotor polyneuropathy, is the most common form of diabetic neuropathy. Although diabetic polyneuropathy is the most important risk factor in cases of diabetic foot, given its ...
Tatsuhito Himeno, Hideki Kamiya, Jiro Nakamura   +2 more
doaj   +2 more sources

Quantitative study and related factors analysis of sciatic neuropathy in type 2 diabetes mellitus patients by elastic imaging virtual tissue imaging quantification technique [PDF]

Hereditas
Background The incidence of diabetic peripheral neuropathy (DPN) is increasing every year for type 2 diabetes mellitus (T2DM) patients, and diabetic polyneuropathy is a common type.
Ruixing Liu, Beibei Yu, Gaopan Cao, Lina Ye, Dan Zhang   +4 more
doaj   +2 more sources

Eplontersen for Hereditary Transthyretin Amyloidosis With Polyneuropathy.

Journal of the American Medical Association (JAMA), 2023
Importance Transthyretin gene silencing is an emerging treatment strategy for hereditary transthyretin (ATTRv) amyloidosis. Objective To evaluate eplontersen, an investigational ligand-conjugated antisense oligonucleotide, in ATTRv polyneuropathy ...
T. Coelho, Wilson Marques, N. Dasgupta, C. Chao, Y. Parman, M. França, Yuh-Cherng Guo, J. Wixner, Long-Sun Ro, Cristian R Calandra, P. Kowacs, J. Berk, L. Obici, F. A. Barroso, M. Weiler, I. Conceição, Shiangtung W. Jung, G. Buchele, Michela Brambatti, Jersey Chen, Steven G. Hughes, Eugene Schneider, N. Viney, Ahmad Masri, Morie Gertz, Yukio Ando, J. Gillmore, S. Khella, P. J. Dyck, M. Waddington Cruz, A. Mazzeo, A. Papagianni, Mazen Dimachkie, Ioannis Zaganas, Edward Gane, M. Luigetti, L. Galán Dávila, Michelle Mezei, Juan Gonzalez Moreno, P. Cintas, D. Pareyson, Rebecca E Traub, Julie Khoury, C. Estol, Merrilee Needham, David John Adams, M. Polydefkis, T. Brannagan, V. Bril, S. Attarian, Marcelo Rugiero, Barbara Distad, Eleni Zamba Papanicolaou, Kon-Ping Lin, Merrill D. Benson, M. Scheinberg   +55 more
semanticscholar   +1 more source

Neurofilament proteins as a potential biomarker in chemotherapy-induced polyneuropathy

JCI Insight, 2022
BACKGROUND Paclitaxel chemotherapy frequently induces dose-limiting sensory axonal polyneuropathy. Given that sensory symptoms are challenging to assess objectively in clinical practice, an easily accessible biomarker for chemotherapy-induced ...
Petra Huehnchen, C. Schinke, N. Bangemann, A. Dordevic, Johannes Kern, Smilla K. Maierhof, L. Hew, Luca Nolte, Péter Körtvélyessy, J. Göpfert, K. Ruprecht, C. Somps, J. Blohmer, J. Sehouli, M. Endres, W. Boehmerle   +15 more
semanticscholar   +1 more source

Contactin-1 is a novel target antigen in membranous nephropathy associated with chronic inflammatory demyelinating polyneuropathy.

Kidney International, 2021
Primary membranous nephropathy (MN) is an autoimmune glomerular disease in which autoantibodies are directed against podocyte proteins. In about 80% of cases the main targeted antigen is the phospholipase A2 receptor 1 (PLA2R1).
M. Le Quintrec, Maxime Teisseyre, N. Bec, E. Delmont, I. Szwarc, H. Perrochia, M. Machet, Anthony Chauvin, N. Mavroudakis, G. Taieb, Luca Lanfranco, C. Rigothier, Boucraut José, Catalano Concetta, C. Geneste, V. Pernin, C. Larroque, J. Devaux, Anais Beyze   +18 more
semanticscholar   +1 more source

The effects of combined physical procedures on the functional status of patients with diabetic polyneuropathy [PDF]

Vojnosanitetski Pregled, 2022
Background/Aim. Diabetic polyneuropathy is a common chronic complication in patients with diabetes mellitus. The aim of this study was to determine the importance of applied physical procedures on the functional status of diabetic polyneuropathy patients
Grbović Vesna, Đukić Svetlana, Stefanović Srđan, Zdravković-Petrović Nataša, Simović Stefan, Jurišić-Škevin Aleksandra   +5 more
doaj   +1 more source

The sensitivity and specificity of the neurological examination in polyneuropathy patients with clinical and electrophysiological correlations. [PDF]

PLoS ONE, 2017
INTRODUCTION:Polyneuropathy is one of the most prevalent neurologic disorders. Although several studies explored the role of the neurological examination in polyneuropathy, they were mostly restricted to specific subgroups of patients and have not ...
Alon Abraham, Majed Alabdali, Abdulla Alsulaiman, Hana Albulaihe, Ari Breiner, Hans D Katzberg, Danah Aljaafari, Leif E Lovblom, Vera Bril   +8 more
doaj   +1 more source

Associations of polyneuropathy with risk of all‐cause and cardiovascular mortality, cardiovascular disease events stratified by diabetes status

Journal of Diabetes Investigation, 2023
Aims/Introduction We investigated the association of polyneuropathy (PN) with all‐cause and cardiovascular (CV) mortality and with cardiovascular disease (CVD) events stratified by diabetes status. Materials and Methods This prospective cohort study used
Kyuho Kim, Su‐Nam Lee, Yu‐Bae Ahn, Seung‐Hyun Ko, Jae‐Seung Yun   +4 more
doaj   +1 more source

Plasma lipid metabolites associate with diabetic polyneuropathy in a cohort with type 2 diabetes

Annals of Clinical and Translational Neurology, 2021
The global rise in type 2 diabetes is associated with a concomitant increase in diabetic complications. Diabetic polyneuropathy is the most frequent type 2 diabetes complication and is associated with poor outcomes.
Amy E. Rumora, K. Guo, Fadhl M Alakwaa, S. T. Andersen, E. Reynolds, M. Jørgensen, D. Witte, H. Tankişi, M. Charles, M. G. Savelieff, B. Callaghan, T. Jensen, E. Feldman   +12 more
semanticscholar   +1 more source

Expert consensus recommendations to improve diagnosis of ATTR amyloidosis with polyneuropathy

Journal of Neurology, 2020
Amyloid transthyretin (ATTR) amyloidosis with polyneuropathy (PN) is a progressive, debilitating, systemic disease wherein transthyretin protein misfolds to form amyloid, which is deposited in the endoneurium. ATTR amyloidosis with PN is the most serious
D. Adams, Y. Ando, J. Beirão, T. Coelho, M. Gertz, J. Gillmore, P. Hawkins, I. Lousada, O. Suhr, G. Merlini   +9 more
semanticscholar   +1 more source