Results 1 to 10 of about 32,057 (203)

Virus Replication as a Phenotypic Version of Polynucleotide Evolution [PDF]

, 2013
In this paper we revisit and adapt to viral evolution an approach based on the theory of branching process advanced by Demetrius, Schuster and Sigmund ("Polynucleotide evolution and branching processes", Bull. Math. Biol.
A. Eyre-Walker, A. Kowald, A. Timm, C. Escarmís, C. J. Thompson, C. Meyer, C. O. Wilke, C. O. Wilke, D. A. Steinhauer, D. R. Rokyta, Diogo Castro, E. Domingo, E. Domingo, E. Lázaro, F. Antoneli, F. Antoneli, F. Gantmacher, Fernando Antoneli, Francisco Bosco, H. A. Orr, H. W. Watson, I. Leuthäusser, J. A. Capitán, J. A. Cuesta, J. A. Cuesta, J. Aguirre, J. Aguirre, J. H. Wilkinson, J. Hermisson, J. J. Bull, J. J. Bull, J. J. Bull, J. Swetina, K. B. Athreya, K. Dietz, L. Demetrius, L. Demetrius, Luiz Mario Janini, M. Delbrück, M. Eigen, M. Eigen, M. Imhof, M. Jiřina, M. Kimmel, M. Parera, M. Ziehe, P. Carrasco, P. D. Keightley, P. Domingo-Calap, P. Jagers, R. Forster, R. M. Gray, R. Miralles, R. Sanjuán, S. C. Manrubia, S. Crotty, S. F. Elena, S. F. Elena, S. Ojosnegros, S. Ojosnegros, T. G. Kurtz, T. Harris, U. Grenander, W. Feller, Y. Zhu   +64 more
core   +2 more sources

Combination of Hyaluronic Acid and Polynucleotides Injection for the Treatment of Cheilitis Simplex

Clinical, Cosmetic and Investigational Dermatology
Kartika Ruchiatan, Yuri Yogya, Ilma Arifani, Reti Hindritiani, Diah Puspitosari, Trustia Rizqandaru, Srie Prihianti Gondokaryono, Pati Aji Achdiat Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin
Ruchiatan K, Yogya Y, Arifani I, Hindritiani R, Puspitosari D, Rizqandaru T, Gondokaryono SP, Achdiat PA   +7 more
doaj   +1 more source

Viscosupplementation in the Therapy for Osteoarthritic Knee

Applied Sciences, 2021
Osteoarthritis (OA) is a degenerative disease that is spreading worldwide due to an aging population. This is not simply a disease caused by worn out joints, but a complex disease accompanied by various mechanisms such as inflammatory reactions.
Junghyun Park, Hue Jung Park, Min Cheol Rho, Jin Joo   +3 more
doaj   +1 more source

Phenanthridine–pyrene conjugates as fluorescent probes for DNA/RNA and an inactive mutant of dipeptidyl peptidase enzyme

Beilstein Journal of Organic Chemistry, 2023
Two novel conjugate molecules were designed: pyrene and phenanthridine-amino acid units with a different linker length between the aromatic fragments. Molecular modelling combined with spectrophotometric experiments revealed that in neutral and acidic ...
Josipa Matić, Tana Tandarić, Marijana Radić Stojković, Filip Šupljika, Zrinka Karačić, Ana Tomašić Paić, Lucija Horvat, Robert Vianello, Lidija-Marija Tumir   +8 more
doaj   +1 more source

Novel Tripodal Polyamine Tris-Pyrene: DNA/RNA Binding and Photodynamic Antiproliferative Activity

Pharmaceutics, 2023
A novel tri-pyrene polyamine (TAL3PYR) bearing net five positive charges at biorelevant conditions revealed strong intramolecular interactions in aqueous medium between pyrenes, characterised by pronounced excimer fluorescence.
Marta Jurković, Marijana Radić Stojković, Ksenija Božinović, Davor Nestić, Dragomira Majhen, Estefanía Delgado-Pinar, Mario Inclán, Enrique García-España, Ivo Piantanida   +8 more
doaj   +1 more source

The dynamics of polynucleotide chain consisting of two different homogeneous sequences, divided by interface [PDF]

Компьютерные исследования и моделирование, 2013
To research dynamics of inhomogeneous polynucleotide DNA chain the Y-model with no dissipation term was used. Basing on this model using numerical methods calculations were carried out, which have shown the behaviour of nonlinear conformational ...
Andrei Anatolevich Grinevich, Artem Andreevich Ryasik, L. V. Yakushevich   +2 more
doaj   +1 more source

Polynucleotide phosphorylase protects against renal tubular injury via blocking mt-dsRNA-PKR-eIF2α axis

Nature Communications, 2023
Renal tubular atrophy is a hallmark of chronic kidney disease. The study by Zhu et al. reveals the protective role of tubular polynucleotide phosphorylase (PNPT1) against renal atrophy by blocking the leakage of mitochondrial dsRNAs into cytoplasm where ...
Yujie Zhu, Mingchao Zhang, Weiran Wang, Shuang Qu, Minghui Liu, Weiwei Rong, Wenwen Yang, Hongwei Liang, Caihong Zeng, Xiaodong Zhu, Limin Li, Zhihong Liu, Ke Zen   +12 more
doaj   +1 more source

Development of an Interaction Assay between Single-Stranded Nucleic Acids Trapped with Silica Particles and Fluorescent Compounds

Journal of Functional Biomaterials, 2012
Biopolymers are easily denatured by heating, a change in pH or chemical substances when they are immobilized on a substrate. To prevent denaturation of biopolymers, we developed a method to trap a polynucleotide on a substrate by hydrogen bonding using ...
R. Maeda, T. Isoda
doaj   +1 more source

Binding to the minor groove of the double-strand, tau protein prevents DNA from damage by peroxidation. [PDF]

PLoS ONE, 2008
Tau, an important microtubule associated protein, has been found to bind to DNA, and to be localized in the nuclei of both neurons and some non-neuronal cells.
Yan Wei, Mei-Hua Qu, Xing-Sheng Wang, Lan Chen, Dong-Liang Wang, Ying Liu, Qian Hua, Rong-Qiao He   +7 more
doaj   +1 more source

The Effect of Divalent Metal Ions on the Temperature Stability of Poly(I:C) Duplex

Journal of Spectroscopy, 2020
The effect of divalent ions on the thermal stability of the double-stranded polynucleotide polyinosinic:polycytidylic acid (poly(I:C)) in a buffer solution (pH 7) was studied by UV absorption spectroscopy and thermal denaturation by measuring the ...
Evgeniya Usenko, Vladimir Valeev, Alexander Glamazda, Victor Karachevtsev   +3 more
doaj   +1 more source