Results 1 to 10 of about 65,968 (266)

An Innovative Lip Boosting Technique Using Polynucleotides: “4-point Cannula Technique” [PDF]

Plastic and Reconstructive Surgery, Global Open
Summary:. The new concept in aesthetic medicine is heading toward regenerative medicine and the use of skin boosters in our practice, so the present case report aimed to evaluate the efficacy of injecting a polynucleotide into the lips for lip ...
Noury Adel, MSc
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B-cell immunodeficiency associated with polynucleotide kinase 3′-phosphatase (PNKP) deficiency [PDF]

Journal of Allergy and Clinical Immunology: Global
Background: DNA repair is crucial for maintaining genomic integrity and plays a significant role in the immune system. Defects in DNA repair pathways are often associated with immunodeficiency, including B-cell defects, which are consistent with the need
Sanami Takada, MD, PhD, Tsubasa Okano, MD, PhD, Kay Tanita, MD, PhD, Kaima Tsukada, PhD, Masato Watanabe, MD, Atsushi Hijikata, PhD, Takuya Naruto, PhD, Tzu-Wen Yeh, PhD, Saki Kasuga, MD, PhD, Sadao Tokimasa, MD, PhD, Mariko Taniguchi-Ikeda, MD, PhD, Reina Ogata, MD, Azusa Ikeda, MD, PhD, Tomohide Goto, MD, PhD, Hitoshi Osaka, MD, PhD, Masatoshi Takagi, MD, PhD, Kohsuke Imai, MD, PhD, Tomohiro Morio, MD, PhD, Mirjam van der Burg, PhD, Mikio Shimada, PhD, Hirokazu Kanegane, MD, PhD   +20 more
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Sequential Bone Repair in Rabbit Sinus Lifts Using Bio-Oss and Hyaluronic Acid–Polynucleotide Gel (Regenfast) [PDF]

Journal of Functional Biomaterials
Background: A comprehensive investigation to associate the use of polynucleotides and hyaluronic acid with bovine bone in maxillary sinus lift procedures in rabbits has not been performed yet.
Nozomi Maniwa, Samuel Porfirio Xavier, Sergio Luis Scombatti de Souza, Erick Ricardo Silva, Daniele Botticelli, Kenzo Morinaga, Shunsuke Baba   +6 more
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Viscosupplementation in the Therapy for Osteoarthritic Knee

Applied Sciences, 2021
Osteoarthritis (OA) is a degenerative disease that is spreading worldwide due to an aging population. This is not simply a disease caused by worn out joints, but a complex disease accompanied by various mechanisms such as inflammatory reactions.
Junghyun Park, Hue Jung Park, Min Cheol Rho, Jin Joo   +3 more
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Phenanthridine–pyrene conjugates as fluorescent probes for DNA/RNA and an inactive mutant of dipeptidyl peptidase enzyme

Beilstein Journal of Organic Chemistry, 2023
Two novel conjugate molecules were designed: pyrene and phenanthridine-amino acid units with a different linker length between the aromatic fragments. Molecular modelling combined with spectrophotometric experiments revealed that in neutral and acidic ...
Josipa Matić, Tana Tandarić, Marijana Radić Stojković, Filip Šupljika, Zrinka Karačić, Ana Tomašić Paić, Lucija Horvat, Robert Vianello, Lidija-Marija Tumir   +8 more
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Novel Tripodal Polyamine Tris-Pyrene: DNA/RNA Binding and Photodynamic Antiproliferative Activity

Pharmaceutics, 2023
A novel tri-pyrene polyamine (TAL3PYR) bearing net five positive charges at biorelevant conditions revealed strong intramolecular interactions in aqueous medium between pyrenes, characterised by pronounced excimer fluorescence.
Marta Jurković, Marijana Radić Stojković, Ksenija Božinović, Davor Nestić, Dragomira Majhen, Estefanía Delgado-Pinar, Mario Inclán, Enrique García-España, Ivo Piantanida   +8 more
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The dynamics of polynucleotide chain consisting of two different homogeneous sequences, divided by interface [PDF]

Компьютерные исследования и моделирование, 2013
To research dynamics of inhomogeneous polynucleotide DNA chain the Y-model with no dissipation term was used. Basing on this model using numerical methods calculations were carried out, which have shown the behaviour of nonlinear conformational ...
Andrei Anatolevich Grinevich, Artem Andreevich Ryasik, L. V. Yakushevich   +2 more
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Polynucleotide phosphorylase protects against renal tubular injury via blocking mt-dsRNA-PKR-eIF2α axis

Nature Communications, 2023
Renal tubular atrophy is a hallmark of chronic kidney disease. The study by Zhu et al. reveals the protective role of tubular polynucleotide phosphorylase (PNPT1) against renal atrophy by blocking the leakage of mitochondrial dsRNAs into cytoplasm where ...
Yujie Zhu, Mingchao Zhang, Weiran Wang, Shuang Qu, Minghui Liu, Weiwei Rong, Wenwen Yang, Hongwei Liang, Caihong Zeng, Xiaodong Zhu, Limin Li, Zhihong Liu, Ke Zen   +12 more
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Binding to the minor groove of the double-strand, tau protein prevents DNA from damage by peroxidation. [PDF]

PLoS ONE, 2008
Tau, an important microtubule associated protein, has been found to bind to DNA, and to be localized in the nuclei of both neurons and some non-neuronal cells.
Yan Wei, Mei-Hua Qu, Xing-Sheng Wang, Lan Chen, Dong-Liang Wang, Ying Liu, Qian Hua, Rong-Qiao He   +7 more
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Development of an Interaction Assay between Single-Stranded Nucleic Acids Trapped with Silica Particles and Fluorescent Compounds

Journal of Functional Biomaterials, 2012
Biopolymers are easily denatured by heating, a change in pH or chemical substances when they are immobilized on a substrate. To prevent denaturation of biopolymers, we developed a method to trap a polynucleotide on a substrate by hydrogen bonding using ...
R. Maeda, T. Isoda
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