Results 91 to 100 of about 79,106 (244)
Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair [PDF]
, 2002 The DNA single-strand break repair (SSBR) protein XRCC1 is required for genetic stability and for embryonic viability. XRCC1 possesses two BRCA1 carboxyl-terminal (BRCT) protein interaction domains, denoted BRCT I and II.
Caldecott, Keith W +2 more
core +3 more sources
Journal of Phycology, EarlyView.Abstract Alkaline phosphatase (AP) plays an important role in phosphorus (P) cycling in aquatic ecosystems, particularly under nutrient limitation. In post‐mining lakes of Czechia, periphyton forms extensive mats despite chronic P deficiency, suggesting dissolved organic P (DOP) may serve as a key P source.
Eliška Konopáčová +5 more
wiley +1 more source
Syntheses and characterizations of the in vivo replicative bypass and mutagenic properties of the minor-groove O2-alkylthymidine lesions. [PDF]
, 2014 Endogenous metabolism, environmental exposure, and treatment with some chemotherapeutic agents can all give rise to DNA alkylation, which can occur on the phosphate backbone as well as the ring nitrogen or exocyclic nitrogen and oxygen atoms of ...
Cai, Qian +3 more
core +1 more source
Journal of Periodontal Research, EarlyView.Hydrogel‐based therapies have proven to be valuable tools to address the unique regeneration challenges of complex multi‐domain periodontal and craniofacial tissues. This review highlights and classifies clinically approved and emerging hydrogel therapies indicated for the regeneration of periodontal and craniofacial tissues.
Z. Gouveia +5 more
wiley +1 more source
Bio-ProtocolZinc-finger (ZF) arrays are compact, sequence-specific polynucleotide-binding domains, which have been used to target the delivery of diverse effector domains, enabling applications such as gene identification, localization, regulation, and editing.
Jingchang Liang +6 more
doaj +1 more source
Solvable models of neighbor-dependent nucleotide substitution processes
, 2005 We prove that a wide class of models of Markov neighbor-dependent substitution processes on the integer line is solvable. This class contains some models of nucleotide substitutions recently introduced and studied empirically by molecular biologists.
Bérard, Jean +2 more
core +3 more sources
Lack of Z-DNA Conformation in Mitomycin-Modified Polynucleotides Having Inverted Circular Dichroism [PDF]
, 1983 Poly(dG-dC)· poly(dG-dC) and Micrococcus lysodeikticus DNA were modified by exposure to reductively activated mitomycin C, an antitumor antibiotic. The resulting covalent drug-polynucleotide complexes displayed varying degrees of CD inversions, which are
Barton, Jacqueline K. +5 more
core +1 more source
Periodontology 2000, EarlyView.Abstract The primary objective is to critically analyze approaches to local therapy for periodontal disease, particularly in light of its well‐established systemic implications. We specifically address common misconceptions and overestimations regarding the potential of local treatments in contrast to their actual clinical effectiveness.
Andrea Mombelli, Alkisti Zekeridou
wiley +1 more source
Hyaluronic acid: A novel approach in regenerative/reconstructive periodontal therapy?
Periodontology 2000, EarlyView.Abstract Background Although hyaluronic acid (HA) has long been used for many medical applications, only in recent years has it gained greater popularity in the field of periodontics because of its biological effects during wound healing. Even today, most clinicians are not aware that more than one type of HA exists and that the extent of its ...
Andrea Pilloni +7 more
wiley +1 more source
Polynucleotide phosphorylase has an impact on cell biology of Campylobacter jejuni
Frontiers in Cellular and Infection Microbiology, 2012 Polynucleotide phosphorylase, encoded by the pnp gene, is known to degrade mRNA, mediating post-transcriptional regulation and may affect cellular functions. The role of PNPase is pleiotropic.
Nabila eHaddad +12 more
doaj +1 more source