Results 101 to 110 of about 95,296 (292)

The Double Face of Base Excision Repair: Preventing and Triggering Double‐Strand Breaks

open access: yesBioEssays, Volume 48, Issue 1, January 2026.
Base excision repair is conserved from bacteria to man, robustly eliminating oxidized bases in DNA and reinserting the appropriate nucleotide to restore an intact double helix. Recent results describe conditions and mechanisms that misregulate long‐patch BER to generate double‐strand breaks, triggering chromosome fragmentation and cell death, altering ...
Susan M. Gasser
wiley   +1 more source

Polynucleotide phosphorylase has an impact on cell biology of Campylobacter jejuni

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
Polynucleotide phosphorylase, encoded by the pnp gene, is known to degrade mRNA, mediating post-transcriptional regulation and may affect cellular functions. The role of PNPase is pleiotropic.
Nabila eHaddad   +12 more
doaj   +1 more source

Linker region is required for efficient nuclear localization of polynucleotide kinase phosphatase.

open access: yesPLoS ONE, 2020
Polynucleotide kinase phosphatase (PNKP) is a DNA repair factor with dual enzymatic functions, i.e., phosphorylation of 5'-end and dephosphorylation of 3'-end, which are prerequisites for DNA ligation and, thus, is involved in multiple DNA repair ...
Kaima Tsukada   +2 more
doaj   +1 more source

The Landscape of Radiofrequency Technology for Skin Rejuvenation

open access: yesHealth Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Aging skin is characterized by reduced tissue volume, weakened fibrous support, and increased laxity, leading to wrinkles and sagging. While surgical methods are effective, noninvasive techniques like radiofrequency (RF) have gained popularity due to their safety, minimal recovery time, and natural‐looking results.
Boyu Zhang, Xingyu Tan, Qi Zhang, Min Wu
wiley   +1 more source

Mycobacteriophage Mcgavigan Uses Noncanonical Bxb1‐Like Repressor for Heterotypic Superinfection Immunity

open access: yesJournal of Basic Microbiology, Volume 66, Issue 1, January 2026.
ABSTRACT Mycobacteriophage Mcgavigan could be a promising candidate for use as a preventative agent against infections with Mycobacterium avium subsp. paratuberculosis. Bioinformatic analysis of the Mcgavigan genome revealed the presence of an operon containing a “Bxb1‐like” repressor.
Natali Shafer   +2 more
wiley   +1 more source

The chemical basis for the origin of the genetic code and the process of protein synthesis [PDF]

open access: yes
The principles upon which the process of protein synthesis and the genetic code were established are elucidated. Extensive work on nuclear magnetic resonance studies of both monomermonomer and monoamino acid polynucleotide interactions is included. A new

core   +1 more source

Polynucleotide Phosphorylase Activity May Be Modulated by Metabolites in Escherichia coli

open access: yesJournal of Biological Chemistry, 2011
RNA turnover is an essential element of cellular homeostasis and response to environmental change. Whether the ribonucleases that mediate RNA turnover can respond to cellular metabolic status is an unresolved question.
S. Nurmohamed   +8 more
semanticscholar   +1 more source

Activity‐restoring mutations in the histamine H3 receptor increase constitutive activity and reduce structural stability

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract The histamine H3 receptor (H3R) is a class A G protein‐coupled receptor (GPCR) that regulates neurotransmitter release in the central nervous system. Although structures of H3R in both inactive and active states have been elucidated, the functional roles of specific residues remain unclear.
Ami Nakajima   +6 more
wiley   +1 more source

Studies of nucleotide sequences in TMV-RNA. II - The action of spleen diesterase [PDF]

open access: yes
Spleen diesterase action on polynucleotide and ribonucleic acid ...
Fraenkel-Conrat, H.   +2 more
core   +1 more source

DNA Nanostructure‐Guided Synthesis of Nanomaterials and Their Applications

open access: yesSmall Structures, Volume 7, Issue 1, January 2026.
This review summarizes the state‐of‐the‐art progress on the synthesis of nanomaterials, e.g., inorganic nanomaterials, organic polymers, and liposomes, based on DNA templates, and several emerging applications of these nanomaterials are also included.
Yiming Xie   +3 more
wiley   +1 more source

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