Results 111 to 120 of about 74,970 (276)

Nickel (II) Ions Interaction with Polynucleotides and DNA of Different GC Composition [PDF]

open access: yesarXiv, 2009
The goal of the work was to study the role of GC alternative dimmers in the binding of DNA with Ni (II) ions. The method of ultraviolet difference spectroscopy has been applied to investigate Ni (II) ions interactions with DNA extracted from Clostridium perfringens, Mice liver (C3HA line), Calf thymus, Salmon sperm, Herring sperm, E.coli, Micrococcus ...
arxiv  

Surface Localized Coacervation Controlled by Bioactive Nanoarchitectonic Polyelectrolyte Multilayers

open access: yesSmall, EarlyView.
Using enzymatically active nanoarchitectured polyelectrolyte multilayers (PEMs), localized liquid–liquid phase separation can be directed from a so‐modified surface. In the presence of urea, PEM‐containing urease layers generate a pH gradient near the surface resulting in the self‐coacervation of a model peptide‐based coacervator.
Jean‐Yves Runser   +10 more
wiley   +1 more source

The chemical basis for the origin of the genetic code and the process of protein synthesis [PDF]

open access: yes
The principles upon which the process of protein synthesis and the genetic code were established are elucidated. Extensive work on nuclear magnetic resonance studies of both monomermonomer and monoamino acid polynucleotide interactions is included. A new

core   +1 more source

Toward Automated DNA Nanoprinting: Advancing the Synthesis of Covalently Branched DNA

open access: yesSmall Methods, EarlyView.
A streamlined synthesis method for covalently branched DNA is developed, laying the foundation for future automated DNA printing devices. Different DNA strands can be covalently transferred to various small molecules, including aromatics and functional porphyrins.
Fangzhou Zhao   +3 more
wiley   +1 more source

Studies of nucleotide sequences in TMV-RNA. II - The action of spleen diesterase [PDF]

open access: yes
Spleen diesterase action on polynucleotide and ribonucleic acid ...
Fraenkel-Conrat, H.   +2 more
core   +1 more source

Mdm2 binding to a conformationally sensitive domain on p53 can be modulated by RNA [PDF]

open access: yes, 2000
Biochemical characterisation of the interaction of mdm2 protein with p53 protein has demonstrated that full-length mdm2 does not bind stably to p53–DNA complexes, contrasting with C-terminal truncations of mdm2 which do bind stably to p53–DNA complexes ...
Abarzua   +29 more
core   +1 more source

The Multifunctional Role of Templates in Chemically Fueled Dynamic Combinatorial Libraries

open access: yesChemSystemsChem, EarlyView.
In template‐based, chemically fueled dynamic combinatorial libraries, inherently labile bonds between library members are formed at the expense of high‐energy molecules, with templates guiding the product distribution. Conversely, we demonstrate that the chemically fueled library affects the properties of the template.
Christine M. E. Kriebisch   +6 more
wiley   +1 more source

Organic Reactivity Matters for the Emergence of Life: Kinetic Barriers and Molecular Diversity Are Suggested as Crucial Factors by Emerging Autonomous System Models

open access: yesChemSystemsChem, EarlyView.
Self‐organisation may result from organic systems fed with free energy provided that reactivity becomes a determining factor. The propensity of carbon to form covalent bonds can give rise to kinetically stable thermodynamically activated compounds possibly undergoing non‐linear kinetic processes.
Robert Pascal
wiley   +1 more source

A nanometric DNA-zwitterionic phospholipid unilamellar vesicle formulation compacted for gene delivery: Adiabatic differential scanning microcalorimetric study [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2004
Complexes between nucleic acids and phospholipid vesicles have been developed as stable non-viral gene delivery vehicles. Currently employed approach uses positively charged lipid species and a helper zwitterionic lipid, the latter being applied for the ...
Erhan S u˙˙leymano(glu
doaj  

Force-induced misfolding in RNA [PDF]

open access: yes, 2009
RNA folding is a kinetic process governed by the competition of a large number of structures stabilized by the transient formation of base pairs that may induce complex folding pathways and the formation of misfolded structures. Despite of its importance
D. Herschlag   +5 more
core   +3 more sources

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