Results 111 to 120 of about 93,488 (303)
Polynucleotide Phosphorylase Activity May Be Modulated by Metabolites in Escherichia coli
Journal of Biological Chemistry, 2011 RNA turnover is an essential element of cellular homeostasis and response to environmental change. Whether the ribonucleases that mediate RNA turnover can respond to cellular metabolic status is an unresolved question.
S. Nurmohamed +8 more
semanticscholar +1 more source
Localisation of the human hSuv3p helicase in the mitochondrial matrix and its preferential unwinding of dsDNA [PDF]
, 2002 We characterised the human hSuv3p protein belonging to the family of NTPases/helicases. In yeast mitochondria the hSUV3 orthologue is a component of the degradosome complex and participates in mtRNA turnover and processing, while in Caenorhabditis ...
Awiszus, K. +10 more
core +2 more sources
A Chromosome Inversion Creates a Supergene for Sex and Colour in Lake Malawi Cichlids
Molecular Ecology, EarlyView.ABSTRACT Cichlid fishes have the highest rates of evolutionary turnover of sex chromosomes among vertebrates. Many large structural polymorphisms in the radiation of cichlids in Lake Malawi are associated with sex chromosomes and may also carry adaptive variation.
Kristen A. Behrens +10 more
wiley +1 more source
Naphthalene diimide bis-guanidinio-carbonyl-pyrrole as a pH-switchable threading DNA intercalator
Beilstein Journal of Organic Chemistry, 2020 A novel naphthalene diimde analogue (NDI) equipped at the imide positions with two guanidinio-carbonyl-pyrrole (GCP) pendant arms interacted significantly stronger with ds-DNA at pH 5 than at pH 7, due to reversible protonation of the GCP arms.
Poulami Jana +3 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 1981 We have compared the behavior in solution of the synthetic polynucleotide poly(dG-m5dC).poly(dG-m5dC) with that of the unmethylated polynucleotide poly(dG-dC).poly(dG-dC).
M. Behe, G. Felsenfeld
semanticscholar +1 more source
Viral Evolution and Adaptation as a Multivariate Branching Process
, 2013 In the present work we analyze the problem of adaptation and evolution of RNA virus populations, by defining the basic stochastic model as a multivariate branching process in close relation with the branching process advanced by Demetrius, Schuster and ...
Antoneli, Fernando +4 more
core +1 more source
Plant, Cell &Environment, EarlyView.ABSTRACT Deep sequencing of ribosome footprints, also known as ribosome profiling (Ribo‐seq), enables the quantification of mRNA translation and a comprehensive view of the translatome landscape. Here, we report an optimised Ribo‐seq protocol and analysis pipeline for the model green alga, Chlamydomonas reinhardtiii (Chlamydomonas).
Yen‐Ling Lin +4 more
wiley +1 more source
Dynamics of Molecular Motors and Polymer Translocation with Sequence Heterogeneity [PDF]
, 2004 The effect of sequence heterogeneity on polynucleotide translocation across a pore and on simple models of molecular motors such as helicases, DNA polymerase/exonuclease and RNA polymerase is studied in detail.
Kafri, Yariv +2 more
core +3 more sources
Clinical and Translational Medicine, Volume 15, Issue 7, July 2025.The interaction between m6A and APA is mediated by the m6A regulator IGF2BP2 and the APA factor CPSF6 The transcripts harbouring m6A modification tend to use the proximal polyadenylation signal (PAS) in ovarian cancer (OC) PUM2 promotes the malignant progression of OC through its m6A methylation and APA processing .
Xin Luo +14 more
wiley +1 more source
Oligo/polynucleotide-based gene modification: strategies and therapeutic potential.
Oligonucleotides, 2011 Oligonucleotide- and polynucleotide-based gene modification strategies were developed as an alternative to transgene-based and classical gene targeting-based gene therapy approaches for treatment of genetic disorders.
R. Geoffrey Sargent +2 more
semanticscholar +1 more source