Results 11 to 20 of about 89,786 (317)
Molecular dynamics study on the mechanism of polynucleotide encapsulation by chitosan
Scientific Reports, 2017 The safe and effective delivery of therapeutic genes into target cell interiors is of great importance in gene therapy. Chitosan has been extensively studied as a gene delivery carrier due to its good biocompatibility and biodegradability.
Jia-Wei Shen +5 more
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Polynucleotide phosphorylase: Not merely an RNase but a pivotal post-transcriptional regulator. [PDF]
PLoS Genetics, 2018 Almost 60 years ago, Severo Ochoa was awarded the Nobel Prize in Physiology or Medicine for his discovery of the enzymatic synthesis of RNA by polynucleotide phosphorylase (PNPase).
Todd A Cameron +2 more
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Identification and characterization of 17 novel polynucleotide microsatellite markers in Ocypode stimpsoni (Decapoda: Ocypodidae) [PDF]
BMC Research NotesObjective The ghost crab Ocypode stimpsoni (Decapoda) is designated as a protected marine species in Korea due to its declining population. In this study, we successfully identified 17 microsatellite markers for O.
Ha Yeun Song +7 more
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International Journal of Nanomedicine, 2012 Mohamad Alameh, Diogo DeJesus, Myriam Jean, Vincent Darras, Marc Thibault, Marc Lavertu, Michael D Buschmann, Abderrazzak MerzoukiInstitute of Biomedical Engineering, Department of Chemical Engineering, École Polytechnique, Montréal,
Alameh M +7 more
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Viscosupplementation in the Therapy for Osteoarthritic Knee
Applied Sciences, 2021 Osteoarthritis (OA) is a degenerative disease that is spreading worldwide due to an aging population. This is not simply a disease caused by worn out joints, but a complex disease accompanied by various mechanisms such as inflammatory reactions.
Junghyun Park +3 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2023 Two novel conjugate molecules were designed: pyrene and phenanthridine-amino acid units with a different linker length between the aromatic fragments. Molecular modelling combined with spectrophotometric experiments revealed that in neutral and acidic ...
Josipa Matić +8 more
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Lipid metabolism in pancreatic cancer: emerging roles and potential targets
Cancer Communications, Volume 42, Issue 12, Page 1234-1256, December 2022., 2022 Abstract Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently <9%. Patients typically present with advanced disease due to vague symptoms or lack of screening for early cancer detection.
Xinpeng Yin +6 more
wiley +1 more source
Novel Tripodal Polyamine Tris-Pyrene: DNA/RNA Binding and Photodynamic Antiproliferative Activity
Pharmaceutics, 2023 A novel tri-pyrene polyamine (TAL3PYR) bearing net five positive charges at biorelevant conditions revealed strong intramolecular interactions in aqueous medium between pyrenes, characterised by pronounced excimer fluorescence.
Marta Jurković +8 more
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High‐Yield Separation of Extracellular Vesicles Using Programmable Zwitterionic Coacervates
Small, Volume 19, Issue 1, January 4, 2023., 2023 Positively charged zwitterionic coacervates are designed to purify extracellular vesicles in high yields. This system combines several advantages of different purification methods, including the scalability of precipitation, the gentle phase of aqueous two‐phase systems, and the programmability of chromatography. Abstract Programmable coacervates based
Carolina Paganini +8 more
wiley +1 more source
The dynamics of polynucleotide chain consisting of two different homogeneous sequences, divided by interface [PDF]
Компьютерные исследования и моделирование, 2013 To research dynamics of inhomogeneous polynucleotide DNA chain the Y-model with no dissipation term was used. Basing on this model using numerical methods calculations were carried out, which have shown the behaviour of nonlinear conformational ...
Andrei Anatolevich Grinevich +2 more
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