Results 271 to 280 of about 93,488 (303)

Methylation in the Study of Polynucleotides

Nature, 1949
ALTHOUGH detailed knowledge of the components of pentose nucleic acids is still incomplete, considerable effort over a long period has been directed towards the problem of the mode of union of the constituent nucleosides. It was early recognized that these units are linked through phosphoric acid residues, and the precise manner in which this takes ...
Kathleen R. Farrar, A. S. Anderson, G. R. Barker   +2 more
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Sensitive and rapid screening of T4 polynucleotide kinase activity and inhibition based on coupled exonuclease reaction and graphene oxide platform.

Analytical Chemistry, 2011
Phosphorylation of DNA with 5'-hydroxyl termini plays a critical role in a majority of normal cellular events, including DNA recombination, DNA replication, and repair of DNA during strand interruption.
Lei Lin, Yang Liu, Xin Zhao, Jinghong Li
semanticscholar   +1 more source

Nucleic acids and polynucleotides

Journal of Cellular Physiology, 1969
The conformation of native double helical DNA is well-known, but it is possible that small regions occur within native DNA, undetectable by X-ray diffraction methods, which have different conformations. Model structures are the synthetic deoxypolynucleotides of defined sequence. Under the conditions used, DNA, poly d(A-T) • poly d(A-T), and poly d(T-G)
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Hypochromicity of oligo- and polynucleotides

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects, 1962
Abstract 1. 1. Syntheses of dinucleoside phosphates containing 6-dimethylaminopurine are described. The ultraviolet-absorption properties of these compounds show that hydrogen bonding is not a direct cause of hypochromicity. 2. The properties of chemically synthesised oligoguanylic acids and of dinucleoside 5′-pyrophosphates are examined and the ...
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Enzymic synthesis of polynucleotides I. polynucleotide phosphorylase of Azotobacter vinelandii

Biochimica et Biophysica Acta, 1956
The isolation, partial purification and some properties of polynucleotide phosphorylase of Azotobacter vinelandii are described. The enzyme catalyzes the synthesis of highly polymerized ribonucleic acid-like polynucleotides from 5′-nucleoside diphosphates with release of orthophosphate. The reaction requires magnesium ions and is reversible.
Marianne Grunberg-Manago, Severo Ochoa, Priscilla J. Ortiz   +2 more
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The Synthesis of Polynucleotides

1979
Publisher Summary This chapter focuses on the chemical synthesis of oligo and poly-nucleotides. Some of the ways in which synthetic polynucleotides have been used in clarifying molecular-biological problems, and comments on areas in which such compounds are currently under investigation are summarized in the chapter.
Morio Ikehara, Eiko Ohtsuka, Alexander F. Markham   +2 more
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On the Theories of Hypochromism in Polynucleotides

Radiation Research, 1963
Conformational changes and resulting effects on spectra involve intramolecular attractions between relatively independent groups such as the bases in polynucleotides. Intramolecular forces (4) and additivity of group properties (1) in polymers are discussed in general by assuming the total wave function of a polymer to be the product of independent ...
Oktay Sinanoğlu, Oktay Sinanoglu
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Mechanism of polynucleotide phosphorylase

Biochemistry, 1989
The de novo polymerization of RNA initiated by polynucleotide phosphorylase from nucleoside diphosphates was examined. End group analysis performed under conditions designed to specifically end label the polymer revealed no evidence for a 5'-pyrophosphate-terminated polymer.
Silvio P. Marchese-Ragona, Michael A. Sulewski, Stephen J. Benkovic, Kenneth A. Johnson   +3 more
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Concepts and software for a rational design of polynucleotide probes.

Environmental Microbiology Reports, 2011
Fluorescence in situ hybridization (FISH) of genes and mRNA is most often based on polynucleotide probes. However, so far there was no published framework for the rational design of polynucleotide probes. The well-established concepts for oligonucleotide
C. Moraru, Gabriel Moraru, B. Fuchs, R. Amann   +3 more
semanticscholar   +1 more source

The Polynucleotide Field

Nature, 1961
Polynucleotides Natural and Synthetic Nucleic Acids. By Robert F. Steiner, and Roland F. Beers Jr. Pp. viii + 404. (Amsterdam: Elsevier Publishing Company; London: D. Van Nostrand Company, Ltd., 1961.) 85s.
openaire   +2 more sources