Results 51 to 60 of about 65,968 (266)

Defects in Polynucleotide phosphorylase impairs virulence in Escherichia coli O157:H7

open access: yesFrontiers in Microbiology, 2015
Polynucleotide phosphorylase (PNPase) is reported to regulate virulence in Salmonella, Yersinia spp. and Campylobacter jejuni, yet its role in Escherichia coli O157:H7 has not been investigated. To gain insights into its roles in E.
Jia eHu, Jia eHu, Meijun eZhu
doaj   +1 more source

Electronic analogue of DNA [PDF]

open access: yesКомпьютерные исследования и моделирование, 2017
It is known that the internal mobility of DNA molecules plays an important role in the functioning of these molecules. This explains the great interest of researchers in studying the internal dynamics of DNA.
L. V. Yakushevich
doaj   +1 more source

Ribosomal Incorporation of Thioxanthone as a Noncanonical Amino Acid Facilitates the Engineering of Photoenzymes

open access: yesChemCatChem, EarlyView.
Thioxanthone is an efficient visible‐light photosensitizer and facilitates reactions that are not known from natural enzymes. It is now possible to incorporate thioxanthone as a noncanonical amino acid (thioX) into proteins by an engineered amino acyl tRNA synthetase.
Marco Seifert   +3 more
wiley   +1 more source

Scaling and Visualization of Nucleotide Sequences [PDF]

open access: yesEPJ Web of Conferences, 2019
Algorithms for scaling and visualization of nucleotide sequences developed in this study allow identifying relationships between the biochemical parameters of DNA and RNA molecules with scale invariance, fractal clusters, nonlinear ordering and symmetry ...
Stepanyan Ivan V., Khussein Abbakar M.
doaj   +1 more source

ENZYMATIC SYNTHESIS OF POLYNUCLEOTIDES

open access: yesJournal of Biological Chemistry, 1957
SUMMARY The relative activity toward different nucleoside diphosphates remains essentially unchanged after 500-fold purification of polynucleotide phosphorylase of Azotobacter v&elan&i suggesting that a single enzyme is involved. The purified enzyme, virtually free of nuclease, contains small amounts of an oligoribonucleotide (with adenine, guanine ...
Matthys Staehelin   +2 more
openaire   +3 more sources

Mechanism of RNA 2′,3′-cyclic phosphate end healing by T4 polynucleotide kinase–phosphatase

open access: yesNucleic Acids Research, 2012
T4 polynucleotide kinase–phosphatase (Pnkp) exemplifies a family of enzymes with 5′-kinase and 3′-phosphatase activities that function in nucleic acid repair.
Ushati Das, S. Shuman
semanticscholar   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

New Fractal Soliton Solutions and Sensitivity Visualization for Double-Chain DNA Model

open access: yesJournal of Function Spaces, 2022
This article discusses dynamics of the fractal double-chain deoxyribonucleic acid model. This structure contains two long elastic homogeneous strands that serve as two polynucleotide chains of deoxyribonucleic acid molecules, bounded by an elastic ...
Zara Hassan   +7 more
doaj   +1 more source

Polynucleotide-Chitosan Complex, an Insoluble but Reactive Form of Polynucleotide.

open access: yesChemical and Pharmaceutical Bulletin, 1997
DNA formed an insoluble complex on mixing with chitosan (poly-D-glucosamine) in solution. The DNA content of the complex was about 50% and the DNA remained insoluble in aqueous media of pH 2-7%; e.g., on treatment of the DNA-chitosan complex with phosphate-buffered saline at pH 7 and 37 degrees C for 26 h, the DNA released into the aqueous phase was ...
Takashi Kubo   +3 more
openaire   +3 more sources

Conserved mycobacterial sRNA B11 regulates lipooligosaccharide synthesis at posttranscriptional level in Mycobacterium marinum

open access: yesmLife, EarlyView.
Abstract Extractable glycolipids of mycobacteria, such as lipooligosaccharides (LOSs), play crucial roles in responding to environmental stress and modulating the host immune response. Although the biosynthesis of LOS is likely regulated at multiple levels to ensure proper composition of the cell wall, the key regulators remain unknown.
Chuan Wang   +6 more
wiley   +1 more source

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