Results 61 to 70 of about 89,786 (317)
Bloch oscillations of a soliton in a molecular chain [PDF]
The European Physical Journal B, 55, 85-87 (2007), 2013 The paper presents results of numerical experiments simulating Bloch oscillations of solitons in a deformable molecular chain in a constant electric field. By the example of a homogeneous polynucleotide chain it is shown that the system under consideration can demonstrate complicated dynamical regimes when at the field intensities less than a certain ...
arxiv +1 more source
Polynucleotide Phosphorylase Mediates a New Mechanism of Persister Formation in Escherichia coli
Microbiology Spectrum, 2023 Despite the identification of many genes and pathways involved in the persistence phenomenon in bacteria, the mechanisms of persistence are not well understood.
Nan Wu +8 more
doaj +1 more source
Micro-RNAS that control myosin expression and myofiber identity [PDF]
, 2015 The present invention relates to the identification of two microRNAs, miR-499 and miR-208b, that repress fast skeletal muscle contractile protein genes. Expression of miR-499 and/or miR-208b can be used to repress fast fiber genes and activate slow fiber
Olson, Eric N., van Rooij, Eva
core +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Regulation of metabolism by miR-378 [PDF]
, 2014 The present invention provides a method of regulating fatty acid metabolism in a cell by contacting the cell with a modulator of miR-378 and/or miR-378* activity or expression.
Carrer, Michele, Olson, Eric N.
core +1 more source
Advanced Engineering Materials, EarlyView.Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley +1 more source
Biology Direct, 2010 Background Almost all known nucleic acid polymerases catalyze 5'-3' polymerization by mediating the attack on an incoming nucleotide 5' triphosphate by the 3'OH from the growing polynucleotide chain in a template dependent or independent manner. The only
Aravind L +2 more
doaj +1 more source
Dual targeting of MIR-208 and MIR-499 in the treatment of cardiac disorders [PDF]
, 2014 The present invention provides a method of treating or preventing cardiac disorders in a subject in need thereof by inhibiting the expression or function of both miR-499 and miR-208 in the heart cells of the subject. In particular, specific protocols for
Olson, Eric S., van Rooij, Eva
core +1 more source
Frontiers in Microbiology, 2019 Pseudomonas aeruginosa is an opportunistic bacterial pathogen that causes various acute and chronic infections. It is intrinsically resistant to a variety of antibiotics. However, production of pyocins during SOS response sensitizes P.
Zheng Fan +11 more
doaj +1 more source
Method for creating polynucleotide and polypeptide sequences [PDF]
, 2003 The invention provides methods for evolving a polynucleotide toward acquisition of a desired property. Such methods entail incubating a population of parental polynucleotide variants under conditions to generate annealed polynucleotides comprising ...
Arnold, Frances +2 more
core +1 more source