Results 71 to 80 of about 48,872 (218)

New Fractal Soliton Solutions and Sensitivity Visualization for Double-Chain DNA Model

open access: yesJournal of Function Spaces, 2022
This article discusses dynamics of the fractal double-chain deoxyribonucleic acid model. This structure contains two long elastic homogeneous strands that serve as two polynucleotide chains of deoxyribonucleic acid molecules, bounded by an elastic ...
Zara Hassan   +7 more
doaj   +1 more source

Viral Evolution and Adaptation as a Multivariate Branching Process [PDF]

open access: yes, 2011
In the present work we analyze the problem of adaptation and evolution of RNA virus populations, by defining the basic stochastic model as a multivariate branching process in close relation with the branching process advanced by Demetrius, Schuster and Sigmund ("Polynucleotide evolution and branching processes", Bull. Math. Biol. 46 (1985) 239-262), in
arxiv   +1 more source

The Reaction of Formaldehyde with Polynucleotides

open access: yesJournal of Biological Chemistry, 1961
Formaldehyde has been used extensively for chemically modifying proteins and for inactivating toxins and viruses, although the precise mode of its action is little understood. In the case of tobacco mosaic virus, however, Fraenkel-Conrat (1) and Staehelin (2) have shown that inactivation of the virus is due to interaction of formaldehyde with the amino
Robert Haselkorn, Paul Doty
openaire   +3 more sources

Polynucleotide phosphorylase has an impact on cell biology of Campylobacter jejuni

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
Polynucleotide phosphorylase, encoded by the pnp gene, is known to degrade mRNA, mediating post-transcriptional regulation and may affect cellular functions. The role of PNPase is pleiotropic.
Nabila eHaddad   +12 more
doaj   +1 more source

Nickel (II) Ions Interaction with Polynucleotides and DNA of Different GC Composition [PDF]

open access: yesarXiv, 2009
The goal of the work was to study the role of GC alternative dimmers in the binding of DNA with Ni (II) ions. The method of ultraviolet difference spectroscopy has been applied to investigate Ni (II) ions interactions with DNA extracted from Clostridium perfringens, Mice liver (C3HA line), Calf thymus, Salmon sperm, Herring sperm, E.coli, Micrococcus ...
arxiv  

Derivatization of unprotected polynucleotides

open access: yesNucleic Acids Research, 1983
A simple and efficient method for attaching amines to the terminal 5'-phosphate of unprotected oligonucleotides or nucleic acids in aqueous solution is described. The method is applicable to low molecular-weight amines, polypeptides, or proteins. The terminal 5'-phosphate of an oligonucleotide or nucleic acid reacts with a water-soluble carbodiimide in
Barbara C.F. Chu   +2 more
openaire   +4 more sources

Driven Polymer Translocation Through a Narrow Pore [PDF]

open access: yes, 1999
Motivated by experiments in which a polynucleotide is driven through a proteinaceous pore by an electric field, we study the diffusive motion of a polymer threaded through a narrow channel with which it may have strong interactions. We show that there is a range of polymer lengths in which the system is approximately translationally invariant, and we ...
arxiv   +1 more source

A nanometric DNA-zwitterionic phospholipid unilamellar vesicle formulation compacted for gene delivery: Adiabatic differential scanning microcalorimetric study [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2004
Complexes between nucleic acids and phospholipid vesicles have been developed as stable non-viral gene delivery vehicles. Currently employed approach uses positively charged lipid species and a helper zwitterionic lipid, the latter being applied for the ...
Erhan S u˙˙leymano(glu
doaj  

Synthesis and polymerization of 1-(2-diallylaminoethyl)pyrimidines

open access: yesDesigned Monomers and Polymers, 2018
We report the preparation and characterization of three pyrimidine-based monomers, specifically: 1-(2-diallylaminoethyl)uracil, 1-(2-diallylaminoethyl)thymine and 1-(2-diallylaminoethyl)cytosine.
Jomana Elaridi   +5 more
doaj   +1 more source

Naphthalene diimide bis-guanidinio-carbonyl-pyrrole as a pH-switchable threading DNA intercalator

open access: yesBeilstein Journal of Organic Chemistry, 2020
A novel naphthalene diimde analogue (NDI) equipped at the imide positions with two guanidinio-carbonyl-pyrrole (GCP) pendant arms interacted significantly stronger with ds-DNA at pH 5 than at pH 7, due to reversible protonation of the GCP arms.
Poulami Jana   +3 more
doaj   +1 more source

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