Results 71 to 80 of about 65,968 (266)

A Small RNA Derived From the 5′ End of the IS200 tnpA Transcript Regulates Multiple Virulence Regulons in Salmonella typhimurium

Molecular Microbiology, EarlyView.
We show deletion of an IS200‐encoded sRNA (5′tnpA) in Salmonella impacts the expression of SPI‐1, flagellar, cysteine, and phsABC regulons. Evidence is presented that, with regard to the SPI‐1 regulon, 5′tnpA may function through base pairing with another sRNA known to regulate SPI1 called PinT.
Ryan S. Trussler, Naomi‐Jean Q. Scherba, Hoda Kooshapour, Michael J. Ellis, Konrad U. Förstner, Matthew Albert, Alexander J. Westermann, David B. Haniford   +7 more
wiley   +1 more source

Crystal structure of human polynucleotide phosphorylase: insights into its domain function in RNA binding and degradation

Nucleic Acids Research, 2011
Human polynucleotide phosphorylase (hPNPase) is a 3′-to-5′ exoribonuclease that degrades specific mRNA and miRNA, and imports RNA into mitochondria, and thus regulates diverse physiological processes, including cellular senescence and homeostasis ...
C. Lin, Yi-Ting Wang, Wei-Zen Yang, Y. Hsiao, Hanna S. Yuan   +4 more
semanticscholar   +1 more source

Dasineura asteriae Reprograms the Flower Gene Expressions of Vegetative Organs to Create Flower‐Like Gall in Aster scaber

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant galls are abnormal growing tissues induced by various parasitic organisms, exhibiting diverse and complex morphologies. Typically, these galls differ significantly in appearance from their host plants. Here, we report that larvae of a parasitic fly generate unique, rosette galls on Aster scaber, a perennial herb. These galls develop from
Kyung‐Hwan Boo, Young Kyoung Oh, Christian Møller, Doseung Lee, Gyeong Lyong Jeon, Donghyuk Kim, Meike Burow, Dominik Kilian Großkinsky, Jiwon Kim, Moon Young Ryu, Bora Lee, Jiye Suh, Chan Man Ha, Thomas Roitsch, Pyung Ok Lim, Frederic Berger, Joo‐Won Suh, Soon‐Il Kim, Tae Rin Oh, Seok Keun Cho, Wanggyu Kim, Sangtae Kim, Key Zung Riu, Seong Wook Yang   +23 more
wiley   +1 more source

Hyaluronic acid: A novel approach in regenerative/reconstructive periodontal therapy?

Periodontology 2000, EarlyView.
Abstract Background Although hyaluronic acid (HA) has long been used for many medical applications, only in recent years has it gained greater popularity in the field of periodontics because of its biological effects during wound healing. Even today, most clinicians are not aware that more than one type of HA exists and that the extent of its ...
Andrea Pilloni, Yoshinori Shirakata, Lorenzo Marini, Darko Božić, Richard J. Miron, Roberto Rotundo, Andreas Stavropoulos, Anton Sculean   +7 more
wiley   +1 more source

Polynucleotide Phosphorylase Activity May Be Modulated by Metabolites in Escherichia coli

Journal of Biological Chemistry, 2011
RNA turnover is an essential element of cellular homeostasis and response to environmental change. Whether the ribonucleases that mediate RNA turnover can respond to cellular metabolic status is an unresolved question.
S. Nurmohamed, H. Vincent, C. Titman, V. Chandran, Michael R. Pears, D. Du, J. Griffin, A. J. Callaghan, B. Luisi   +8 more
semanticscholar   +1 more source

How to Treat Skin Quality: A Consensus‐Based Treatment Algorithm and Expert Guidance

Journal of Cosmetic Dermatology, Volume 24, Issue S4, September 2025.
ABSTRACT Introduction Skin quality can be described using four emergent perceptual categories (EPCs): skin tone evenness, skin surface evenness, skin firmness, and skin glow. While the publication in which the EPCs were originally described by Goldie et al.
Martina Kerscher, Kate Goldie, Cyro Hirano, Stephen Lowe, Kavita Mariwalla, Milton Moore, Je‐Young Park, Dusan Sajic, Sonja Sattler, Julieta Spada, Vasanop Vachiramon, Bianca Viscomi   +11 more
wiley   +1 more source

Synthesis and polymerization of 1-(2-diallylaminoethyl)pyrimidines

Designed Monomers and Polymers, 2018
We report the preparation and characterization of three pyrimidine-based monomers, specifically: 1-(2-diallylaminoethyl)uracil, 1-(2-diallylaminoethyl)thymine and 1-(2-diallylaminoethyl)cytosine.
Jomana Elaridi, Alaa Ezzeddine, Lara Abramian, Ali Koubeissi, Nikolay Vladimirov, Kamal H. Bouhadir   +5 more
doaj   +1 more source

Optimised Ribosome Profiling Reveals New Insights Into Translational Regulation in Synchronised Chlamydomonas reinhardtii Cultures

Plant, Cell &Environment, Volume 48, Issue 9, Page 6982-7000, September 2025.
ABSTRACT Deep sequencing of ribosome footprints, also known as ribosome profiling (Ribo‐seq), enables the quantification of mRNA translation and a comprehensive view of the translatome landscape. Here, we report an optimised Ribo‐seq protocol and analysis pipeline for the model green alga, Chlamydomonas reinhardtiii (Chlamydomonas).
Yen‐Ling Lin, Eva Yuhua Kuo, Shih‐Yi Wang, Chih‐Chi Lee, Su‐Chiung Fang   +4 more
wiley   +1 more source

Naphthalene diimide bis-guanidinio-carbonyl-pyrrole as a pH-switchable threading DNA intercalator

Beilstein Journal of Organic Chemistry, 2020
A novel naphthalene diimde analogue (NDI) equipped at the imide positions with two guanidinio-carbonyl-pyrrole (GCP) pendant arms interacted significantly stronger with ds-DNA at pH 5 than at pH 7, due to reversible protonation of the GCP arms.
Poulami Jana, Filip Šupljika, Carsten Schmuck, Ivo Piantanida   +3 more
doaj   +1 more source

Photodynamic Therapy and Dietary Antioxidants: A Dual Strategy for Genome Stability and DNA Damage Repair

Cancer Medicine, Volume 14, Issue 15, August 2025.
ABSTRACT Background Photodynamic therapy (PDT) is an emerging cancer treatment that relies on photosensitizers (PS) activated by specific light wavelengths to produce reactive oxygen species (ROS), effectively targeting malignant cells. However, ROS can also harm surrounding healthy tissues, necessitating strategies to reduce unintended DNA damage ...
J. P. Jose Merlin, Sheeja S. Rajan, Heidi Abrahamse   +2 more
wiley   +1 more source