Results 81 to 90 of about 65,968 (266)

Analytical Study of Lanolin as Potential Biomarker of Prehistoric Sheep‐Shearing Practice

Chemistry–Methods, Volume 5, Issue 8, August 2025.
Lanolin, a complex wax found on sheep wool, accumulates on shearing tools, such as flint and obsidian blades, used since the Neolithic. This study explores lanolin's degradation patterns as a potential biomarker for prehistoric sheep‐shearing practices, employing micro‐Fourier transformed infrared spectroscopy, hyperspectral imaging, and gas ...
Claudia Adsuar Fuster, Francesco Caruso, Olivia Gómez‐Laserna, Martina Romani, Ramón J. Barrio, Josep Maria Vergès, Vincenza Forgia, Maite Maguregui, Asier Vallejo   +8 more
wiley   +1 more source

Exploring the Potential and Advancements of Circular RNA Therapeutics

Exploration, Volume 5, Issue 4, August 2025.
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang, Lianqing Wang, Chunbo Dong, Jialong Liu, Guoxin Cui, Shan Gao, Zhida Liu   +6 more
wiley   +1 more source

Prediction of Proliferation Rate of Pre‐Osteoblasts Using Raman Spectroscopy and Machine Learning Models

Journal of Raman Spectroscopy, Volume 56, Issue 8, Page 700-710, August 2025.
The main processes involved in predicting the pre–osteoblast proliferation rate using Raman spectroscopy and machine learning. ABSTRACT This novel study focuses on using Raman spectroscopy and machine learning (ML) models to forecast the murine pre‐osteoblast (OB) proliferation rate.
Sai S. Sudha, Angshuman Baradwaz, Ahmad Y. Javaid, Ambalangodage C. Jayasuriya   +3 more
wiley   +1 more source

Dual Modes of Interaction between XRCC4 and Polynucleotide Kinase/Phosphatase

Journal of Biological Chemistry, 2010
XRCC4 plays a crucial role in the nonhomologous end joining (NHEJ) pathway of DNA double-strand break repair acting as a scaffold protein that recruits other NHEJ proteins to double-strand breaks. Phosphorylation of XRCC4 by protein kinase CK2 promotes a
R. Mani, Yaping Yu, Shujuan Fang, Meiling Lu, M. Fanta, Angela E. Zolner, Nasser Tahbaz, D. Ramsden, D. Litchfield, S. Lees-Miller, M. Weinfeld   +10 more
semanticscholar   +1 more source

Complete Mitochondrial Genomes Provide Evidence of a Killer Whale Refugium Off the Coast of Japan During the Last Glacial Maximum

Journal of Biogeography, Volume 52, Issue 8, August 2025.
ABSTRACT Aim During glacial periods, highly mobile species often shifted to warmer, ice‐free regions known as refugia, which frequently maintained higher genetic diversity than newly colonised areas after glacial retreat. We analyse complete mitogenome sequences from 11 killer whale samples in Nemuro Strait to test the hypothesis that waters around ...
Olga A. Filatova, Ivan D. Fedutin, Ekaterina A. Borisova, Ilya G. Meschersky, Marina V. Shitova, Erich Hoyt, Andrew D. Foote   +6 more
wiley   +1 more source

Polynucleotide phosphorylase is implicated in homologous recombination and DNA repair in Escherichia coli

BMC Microbiology, 2017
Background Polynucleotide phosphorylase (PNPase, encoded by pnp) is generally thought of as an enzyme dedicated to RNA metabolism. The pleiotropic effects of PNPase deficiency is imputed to altered processing and turnover of mRNAs and small RNAs, which ...
Thomas Carzaniga, Giulia Sbarufatti, Federica Briani, Gianni Dehò   +3 more
doaj   +1 more source

Nol9 is a novel polynucleotide 5′-kinase involved in ribosomal RNA processing

EMBO Journal, 2010
In a cell, an enormous amount of energy is channelled into the biogenesis of ribosomal RNAs (rRNAs). In a multistep process involving a large variety of ribosomal and non‐ribosomal proteins, mature rRNAs are generated from a long polycistronic precursor.
Katrin Heindl, Javier Martinez
semanticscholar   +1 more source

A Novel Peel to Prevent Post‐Inflammatory Hyperpigmentation After CO2 Resurfacing for Acne Scars

Journal of Cosmetic Dermatology, Volume 24, Issue 8, August 2025.
ABSTRACT Background Atrophic acne scars are a common dermatological concern, often requiring fractional carbon dioxide (CO2) laser resurfacing for effective treatment. However, in darker skin types (Fitzpatrick III–V), the high risk of post‐inflammatory hyperpigmentation (PIH) remains a significant limitation, affecting treatment outcomes.
Xiaozhun Hang, Davin Sui Lim
wiley   +1 more source

DNA repair deficiency in neuropathogenesis: when all roads lead to mitochondria

Translational Neurodegeneration, 2019
Mutations in DNA repair enzymes can cause two neurological clinical manifestations: a developmental impairment and a degenerative disease. Polynucleotide kinase 3′-phosphatase (PNKP) is an enzyme that is actively involved in DNA repair in both single and
Luis Bermúdez-Guzmán, Alejandro Leal
doaj   +1 more source

Nucleotide exchange reactions catalysed by ribonuclease and spleen phosphodiesterase. 2. Synthesis of polynucleotides [PDF]

, 1955
L. A. Heppel, Paul R. Whitfeld, Roy Markham   +2 more
openalex   +1 more source