Advanced glycation end products modulate transcriptional regulation in mesangial cells [PDF]
Advanced glycation end products modulate transcriptional regulation in mesangial cells. Advanced glycation end products (AGEs) stimulate synthesis of extracellular matrix (ECM) in a receptor-mediated manner on mesangial cells.
Iehara, Noriyuki +4 more
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In Vitro Repair of Single–strand Breaks in γ-irradiated DNA by Polynucleotide Ligase
SummaryThe ability of polynucleotide ligase to eliminate single-strand breaks in γ-irradiated DNA was studied. The irradiated DNA was first labelled at the 5′-end of the break with 32P-phosphate and treated in vitro with polynucleotide ligase. In phosphoester-bonds joined by the ligase, the incorporated 32P-phosphate is resistant to subsequent ...
Jacobs, A., Bopp, A., Hagen, U.
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Thermodynamic simulation of deoxyoligonucleotide hybridization, polymerization, and ligation [PDF]
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1997.Includes bibliographical references (leaves 54-55).by Alexander J.
Hartemink, Alexander J. (Alexander John), 1972-
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Analysis of epidermis- and mesophyll-specific transcript accumulation in powdery mildew-inoculated wheat leaves [PDF]
Powdery mildew is an important disease of wheat caused by the obligate biotrophic fungus Blumeria graminis f. sp. tritici. This pathogen invades exclusively epidermal cells after penetrating directly through the cell wall.
Abderhalden, Olaf +3 more
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Polynucleotide ligase from myeloid and lymphoid tissues. [PDF]
T, Lindahl, G M, Edelman
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Polynucleotide Ligase Activity in Adenovirus-Infected Human Embryonic Kidney Cell Cultures
SummaryCell-free extracts prepared from human embryonic kidney (HEK) cultures after infection with adenovirus 2 or 12 had a decreased ability to repair single-strand breaks in the HEK cell DNA substrate. The apparent loss of polynucleotide ligase activity found in infected cells may be related to the adenovirus-induced inhibition of HEK cell DNA ...
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Expression, Enzymatic Activities and Subcellular Localization of Hepatitis E Virus and Semliki Forest Virus Replicase Proteins [PDF]
Viruses are submicroscopic, infectious agents that are obligate intracellular parasites. They adopt various types of strategies for their parasitic replication and proliferation in infected cells.
Perttilä, Julia
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Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD+-dependent polynucleotide ligases. [PDF]
Unciuleac MC, Goldgur Y, Shuman S.
europepmc +1 more source
Microhomology-mediated DNA strand annealing and elongation by human DNA polymerases λ and β on normal and repetitive DNA sequences [PDF]
‘Classical' non-homologous end joining (NHEJ), dependent on the Ku70/80 and the DNA ligase IV/XRCC4 complexes, is essential for the repair of DNA double-strand breaks. Eukaryotic cells possess also an alternative microhomology-mediated end-joining (MMEJ)
Crespan, Emmanuele +3 more
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A polynucleotide ligase from polyoma virus-infected mouse cells [PDF]
P, Beard, J D, Pitts
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