Results 51 to 60 of about 19,008 (171)
Molecular Microbiology, Volume 126, Issue 2, Page 190-207, August 2026.Here, we demonstrate that polysaccharide chain length regulation plays a distinct role in enabling formation of a cyclic molecule important for the bacterial cell surface. However, this function is necessary, but not sufficient for the cyclic molecule's biosynthesis.
Joseph F. Carr +4 more
wiley +1 more source
, 1993 We have measured the effects of eight distamycin and two anthracycline derivatives on polynucleotide joining and self-adenylating activities of human DNA ligase I and rat DNA ligases I and III.
M Lestingi +4 more
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Chemical Syntheses of 3′ and 5′ Phosphorylated Oligonucleotides: An Overview
European Journal of Organic Chemistry, Volume 29, Issue 21, 4 June 2026.This review provides an overview of the various chemical methods employed in the synthesis of oligonucleotides bearing a phosphate group at their 3′ or 5′ end. Notably, it presents modified phosphoramidites and supports developed for this purpose. Oligonucleotides (ON) with a phosphate monoester group at their 3′ or 5′ end have applications in many ...
Rémy Lartia
wiley +1 more source
SnapShot:Types of ubiquitin ligases
, 2016 Ubiquitination is a post-translational modification of proteins involved in a variety of cellular processes. Ubiquitination requires the sequential action of three enzymes: E1 (ubiquitin-activating enzymes), E2 (ubiquitin-conjugating enzymes), and E3 ...
Morreale, Francesca Ester, Walden, Helen
core +1 more source
Characterisation of ATP-Dependent Mur Ligases Involved in the Biogenesis of Cell Wall Peptidoglycan in Mycobacterium tuberculosis [PDF]
, 2013 ATP-dependent Mur ligases (Mur synthetases) play essential roles in the biosynthesis of cell wall peptidoglycan (PG) as they catalyze the ligation of key amino acid residues to the stem peptide at the expense of ATP hydrolysis, thus representing ...
Nicholas H Keep +29 more
core +1 more source
Developing as assay to screen inhibitors for various ATP-dependent ligases [PDF]
, 2009 DNA ligases (EC.6.5.1.1) are key enzymes that catalyze the formation of phosphodiester bonds at single-stranded or double-stranded breaks between adjacent 5’-PO4 and 3’-OH groups of DNA. These enzymes are essential guardians of genomic integrity and have
Kaur, L.
core +1 more source
Biomaterials for polynucleotide delivery to anchorage-independent cells
, 2017 Comparison of various chemical vectors used for polynucleotide delivery to mammalian anchorage-independent cells.
Aysha S. Ansari +2 more
core +1 more source
In Vitro Repair of Single–strand Breaks in γ-irradiated DNA by Polynucleotide Ligase
International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1972 SummaryThe ability of polynucleotide ligase to eliminate single-strand breaks in γ-irradiated DNA was studied. The irradiated DNA was first labelled at the 5′-end of the break with 32P-phosphate and treated in vitro with polynucleotide ligase. In phosphoester-bonds joined by the ligase, the incorporated 32P-phosphate is resistant to subsequent ...
Jacobs, A., Bopp, A., Hagen, U.
openaire +3 more sources
Ubiquitin Ligases in Cholesterol Metabolism [PDF]
, 2014 To maintain cholesterol homeostasis, the processes of cholesterol metabolism are regulated at multiple levels including transcription, translation, and enzymatic activity.
Wei Jiang, Bao-Liang Song
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Role of polynucleotide kinase/phosphatase in mitochondrial DNA repair
, 2011 Mutations in mitochondrial DNA (mtDNA) are implicated in a broad range of human diseases and in aging. Compared to nuclear DNA, mtDNA is more highly exposed to oxidative damage due to its proximity to the respiratory chain and the lack of protection ...
Nasser Tahbaz +2 more
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