Results 101 to 110 of about 43,987 (256)
Genome-Wide Study of mRNA Degradation and Transcript Elongation in Escherichia coli [PDF]
An essential part of gene expression is the coordination of RNA synthesis and degradation, which occurs in the same cellular compartment in bacteria.
Chen, Huiyi+3 more
core +2 more sources
Field effect transistor biosensors for healthcare monitoring
Amidst the growing need for healthcare monitoring, field effect transistor (FET) biosensors stand out for their high sensitivity and rapid detection capabilities. The review delves into sensor design and operational principles highlighting their application in biomarker detection for diseases.
Zhicheng Zhang+5 more
wiley +1 more source
Regulatory Mechanisms of Exoribonuclease PNPase and Regulatory Small RNA on T3SS of Dickeya dadantii
The type III secretion system (T3SS) is an essential virulence factor for many bacterial pathogens. Polynucleotide phosphorylase (PNPase) is one of the major exoribonucleases in bacteria and plays important roles in mRNA degradation, tRNA processing, and
Quan Zeng+3 more
doaj +1 more source
Rat liver mitochondrial polynucleotide phosphorylase
We have recently isolated, partially purified and demonstrated the specificity of a polynucleotide phosphorylase from crude guinea-pig liver nuclei [ 1,2] The enzyme was associated with membrane lipids and catalysed the phosphorolysis of polyribonucleotides to ribonucleoside diphosphates.
Yew Phew See, P. S. Fitt
openaire +3 more sources
A Glance into the Near Future: Cultivated Meat from Mammalian and Insect Cells
Growing demand for meat and environmental concerns are driving the search for sustainable alternatives for meat production. Cultured meat from animal stem cells, particularly insect stem cells, is emerging as an efficient, economical, and environmentally friendly option.
Fabiana Giglio+9 more
wiley +1 more source
Strategies for Detecting Aminoacylation and Aminoacyl‐tRNA Editing in vitro and in Cells
Abstract Aminoacyl‐tRNA synthetases (aaRSs) maintain translational fidelity by ensuring the formation of correct aminoacyl‐tRNA pairs. Numerous point mutations in human aaRSs have been linked to disease phenotypes. Structural studies of aaRSs from human pathogens encoding unique domains support these enzymes as potential candidates for therapeutics ...
Rylan R. Watkins+2 more
wiley +1 more source
Bottom‐Up Synthesized Glucan Materials: Opportunities from Applied Biocatalysis
Linear d‐glucans, simple yet versatile polysaccharides, shape nanostructures crucial for biomaterial development. Shifting from top‐down to bottom‐up synthesis using natural and engineered enzymes provides meticulous control over polymer structures, fostering diversification for macromolecular materials.
Chao Zhong, Bernd Nidetzky
wiley +1 more source
DNA double strand breaks, if unrepaired, pose a threat to the cell because they can cause a wide variety of genetic alteration and apoptosis. Therefore, DNA double‐strand break repair pathways are critical for the survival of all organisms.
M. Spence, Lee A. Uranga, S. Lusetti
semanticscholar +1 more source
Single‐Molecule Electrical Profiling of Peptides and Proteins
This work presents a timely overview of the prominent research progress in peptide and protein‐related studies through single‐molecule electrical techniques, including single‐molecule junction, single‐molecule field‐effect transistor (FET), and nanopore.
Hongyu Ju+6 more
wiley +1 more source
Antibiotic influx and efflux in Pseudomonas aeruginosa: Regulation and therapeutic implications
This work comprehensively summarized the regulatory networks of the major porin proteins and efflux pumps that play critical roles in antibiotic influx and efflux in Pseudomonas aeruginosa. It also discussed promising therapeutic approaches to combat multidrug‐resistant P.
Weiyan Wu, Jiahui Huang, Zeling Xu
wiley +1 more source