Results 111 to 120 of about 40,696 (222)
Nickel (II) Ions Interaction with Polynucleotides and DNA of Different GC Composition [PDF]
arXiv, 2009 The goal of the work was to study the role of GC alternative dimmers in the binding of DNA with Ni (II) ions. The method of ultraviolet difference spectroscopy has been applied to investigate Ni (II) ions interactions with DNA extracted from Clostridium perfringens, Mice liver (C3HA line), Calf thymus, Salmon sperm, Herring sperm, E.coli, Micrococcus ...
arxiv
Synthetic and Systems Biotechnology, 2017 The usefulness of genetic/metabolic engineering for further improvement of industrial strains is subject of discussion because of the general lack of knowledge on genetic alterations introduced by iterative cycles of random mutagenesis in such strains ...
Eser Ünsaldı +4 more
doaj +1 more source
Driven Polymer Translocation Through a Narrow Pore [PDF]
, 1999 Motivated by experiments in which a polynucleotide is driven through a proteinaceous pore by an electric field, we study the diffusive motion of a polymer threaded through a narrow channel with which it may have strong interactions. We show that there is a range of polymer lengths in which the system is approximately translationally invariant, and we ...
arxiv +1 more source
ENZYMATIC SYNTHESIS OF POLYNUCLEOTIDES
Journal of Biological Chemistry, 1957 SUMMARY The relative activity toward different nucleoside diphosphates remains essentially unchanged after 500-fold purification of polynucleotide phosphorylase of Azotobacter v&elan&i suggesting that a single enzyme is involved. The purified enzyme, virtually free of nuclease, contains small amounts of an oligoribonucleotide (with adenine, guanine ...
Matthys Staehelin +2 more
openaire +3 more sources
Solvable models of neighbor-dependent nucleotide substitution processes [PDF]
arXiv, 2005 We prove that a wide class of models of Markov neighbor-dependent substitution processes on the integer line is solvable. This class contains some models of nucleotide substitutions recently introduced and studied empirically by molecular biologists. We show that the polynucleotide frequencies at equilibrium solve explicit finite-size linear systems ...
arxiv
Computational evolution of an RNA-binding protein towards enhanced oxidized-RNA binding
Computational and Structural Biotechnology Journal, 2020 The oxidation of RNA has been implicated in the development of many diseases. Among the four ribonucleotides, guanosine is the most susceptible to oxidation, resulting in the formation of 8-oxo-7,8-dihydroguanosine (8-oxoG). Despite the limited knowledge
Juan C. Gonzalez-Rivera +9 more
doaj
Binding of $TMPyP^{3+}$ porphyrin to poly(A)-poly(U) polynucleotide: a spectroscopic study [PDF]
arXivThe porphyrins are macrocyclic compounds widely used as photosensitizers in anticancer photodynamic therapy. The binding of a tricationic meso-tris(N-methylpyridinium)-porphyrin, $TMPyP^{3+}$, to poly(A)-poly(U) polynucleotide has been studied in neutral buffered solution, pH6.9, of low and near-physiological ionic strength in a wide range of molar ...
arxiv
Mitochondria facilitate neuronal differentiation by metabolising nuclear-encoded RNA
Cell Communication and SignalingMitochondrial activity directs neuronal differentiation dynamics during brain development. In this context, the long-established metabolic coupling of mitochondria and the eukaryotic host falls short of a satisfactory mechanistic explanation, hinting at ...
Filip Vujovic +5 more
doaj +1 more source
Binding of Pheophorbide-a methyl ester to nucleic acids of different secondary structures: A spectroscopic study [PDF]
Biophysical Bulletin (2009) v. 23(2), p. 20-29 (in Russian), 2018 Binding of neutral Pheophorbide-a methyl ester (MePheo-a) to various synthetic polynucleotides, double-stranded poly(A)-poly(U), poly(G)-poly(C) and four-stranded poly(G), as well as to calf thymus DNA, was studied using the methods of absorption and polarized fluorescent spectroscopy.
arxiv
The Generalized Model of Polypeptide Chain Describing the Helix-Coil Transition in Biopolymers [PDF]
arXiv, 2005 In this paper we summarize some results of our theoretical investigations of helix-coil transition both in single-strand (polypeptides) and two-strand (polynucleotides) macromolecules. The Hamiltonian does not contain any parameter designed especially for helix-coil transition and uses pure molecular microscopic parameters.
arxiv