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Synthetic nanocarriers for the delivery of polynucleotides to the eye [PDF]
This is the accepted manuscript of the following article: Saraiva, S., Castro-López, V., Pañeda, C., & Alonso, M. (2017). Synthetic nanocarriers for the delivery of polynucleotides to the eye. European Journal Of Pharmaceutical Sciences, 103, 5-18.
María José Alonso Fernández +1 more
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Polynucleotides X. Oligonucleotides and their association with polynucleotides
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1967Abstract Titration studies on a series of oligo (A)'s are described and the thermal stability of the structural form at acid pH has been examined. The stability of complexes formed between oligonucleotides and a complementary polynucleotide has also been studied using homologous series of oligo (A)'s, (C)'s, (I)'s, and (U)'s, and a wide variety of ...
A M, Michelson, C, Monny
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This randomized, double-blind clinical trial was conducted over 16 weeks to assess the efficacy and safety profile of intra-articular polynucleotides gel injections in the treatment of knee osteoarthritis associated with persistent knee pain. 60 patients
Stefano Marco Paolo Rossi
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Model for the elongation of polynucleotide chains by polynucleotide phosphorylase
Journal of Molecular Biology, 1970Abstract The experiments described in this paper were designed to elucidate the mechanism of elongation of a polynucleotide chain catalysed by polynucleotide phosphorylase. The problem has been approached in three different ways, essentially: (1) examination of the size distribution of the end products isolated during the course of the reaction; (2 ...
M N, Thang +2 more
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