Results 111 to 120 of about 80,646 (211)

An unusually high substitution rate in transplant-associated BK polyomavirus in vivo is further concentrated in HLA-C-bound viral peptides.

PLoS Pathogens, 2018
Infection with human BK polyomavirus, a small double-stranded DNA virus, potentially results in severe complications in immunocompromised patients. Here, we describe the in vivo variability and evolution of the BK polyomavirus by deep sequencing.
Pilar Domingo-Calap, Benjamin Schubert, Mélanie Joly, Morgane Solis, Meiggie Untrau, Raphael Carapito, Philippe Georgel, Sophie Caillard, Samira Fafi-Kremer, Nicodème Paul, Oliver Kohlbacher, Fernando González-Candelas, Seiamak Bahram   +12 more
doaj   +1 more source

Polyomavirus specific cellular immunity: from BK-virus-specific cellular immunity to BK-virus-associated nephropathy ?

Frontiers in Immunology, 2015
In renal transplantation, BK-virus-associated nephropathy has emerged as a major complication, with a prevalence of 5–10% and graft loss in >50% of cases. BK-virus is a member of the Polyomavirus family and rarely induces apparent clinical disease in the
manon edekeyser, helene efrancois, severine ebeaudreuil, Antoine eDurrbach   +3 more
doaj   +1 more source

Polyomavirus – an emergent pathogen in transplant recipients [PDF]

, 2007
Medical centers that work with transplants often face opportunisticinfections that demand specific tools to make diagnosis. Theprevalence of latent polyomavirus infections is high, and the mostcommon site of latency of the most prevalent polyomavirus in ...
Bárbara Tengaten Fontanelle, Cláudio Osmar Pereira Alexandre, Juliana de Moura Montagner, Regina Barbosa Schroeder, Tatiana Ferreira Michelon, Alexandre Tavares Duarte de Oliveira, Márcia Silveira Graudenz, Janaina Gomes da Silveira, Jorge Neumann   +8 more
core  

Investigation of the antiviral effects of artesunate on BK and JC polyomavirus replication [PDF]

, 2014
The ubiquitous human BK and JC polyomaviruses cause the diseases polyomavirus-associated nephropathy, hemoragic cystitis and progressive multifocal leukoencephalopathy in immunosuppressed patients.
Sharma, Biswa Nath
core  

BK Polyomavirus-Associated Nephropathy and Hemorrhagic Cystitis in Transplant Recipients—What We Understand and What Remains Unclear

Viruses
The reactivation of BK polyomavirus (BKPyV) during severe immunosuppression plays a crucial role in two significant syndromes observed in transplant recipients: BK polyomavirus-associated nephropathy (BKPyVAN) in kidney transplant patients and BK ...
Tang-Her Jaing, Yi-Lun Wang, Tsung-Yen Chang   +2 more
doaj   +1 more source

Renal Allograft Biopsies with Polyomavirus BK Nephropathy: Turin Transplant Center, 2015-19. [PDF]

Viruses, 2020
Zanotto E, Allesina A, Barreca A, Sidoti F, Gallo E, Bottino P, Iannaccone M, Bianco G, Biancone L, Cavallo R, Costa C.   +10 more
europepmc   +1 more source

Development of a Nucleic Acid Lateral Flow Immunoassay for the Detection of Human Polyomavirus BK. [PDF]

Diagnostics (Basel), 2020
Huang YH, Yu KY, Huang SP, Chuang HW, Lin WZ, Cherng JH, Hung YW, Yeh MK, Hong PD, Liu CC.   +9 more
europepmc   +1 more source

Correlations between plasma BK viral load, pathological findings, and prognosis in BK polyomavirus-associated nephropathy after kidney transplantation

Renal Replacement Therapy
Background BK polyomavirus-associated nephropathy (BKPyVAN) is a significant risk factor for graft loss after kidney transplantation, with pathological staging defined by the Banff Working Group.
Yuki Shimamoto, Asami Takeda, Kenta Futamura, Ayano Ienaga, Tomoki Himeno, Yuki Hasegawa, Manabu Okada, Takahisa Hiramitsu, Yuko Miwa, Shunji Narumi, Yoshihiko Watarai, Takaaki Kobayashi   +11 more
doaj   +1 more source

BK Polyomavirus, thyroïdites auto-immunes et goitre

, 2017
Introduction : les thyroïdites auto-immunes (TAI) sont fréquentes et leur physiopathologie est mal connue. Elles sont souvent associées à un goitre. Parmi les facteurs à l'origine de ces entités pathologiques, on suspecte le rôle des infections virales ...
Desdoits, Franklin
core   +1 more source

Clinical Efficacy of Intravenous Immunoglobulin for BK Polyomavirus-Associated Nephropathy After Living Kidney Transplantation

Therapeutics and Clinical Risk Management, 2020
Soichi Matsumura,1 Taigo Kato,1,2 Ayumu Taniguchi,1 Masataka Kawamura,1 Shigeaki Nakazawa,1 Tomoko Namba-Hamano,3 Toyofumi Abe,1 Norio Nonomura,1 Ryoichi Imamura1 1Department of Urology, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan;
Matsumura S, Kato T, Taniguchi A, Kawamura M, Nakazawa S, Namba-Hamano T, Abe T, Nonomura N, Imamura R   +8 more
doaj