Results 181 to 190 of about 7,381 (220)

Distant Polypharmacology among MLP Chemical Probes

ACS Chemical Biology, 2014
Small molecules are essential tool compounds to probe the role of proteins in biology and advance toward more efficient therapeutics. However, they are used without a complete knowledge of their selectivity across the entire proteome, at risk of confounding their effects due to unknown off-target interactions.
Albert A, Antolín, Jordi, Mestres
openaire   +2 more sources

Polypharmacology in Clinical Applications: Neurological Polypharmacology

2022
Zhiguo Wang, Baofeng Yang
openaire   +1 more source

Polypharmacology in Clinical Applications—Anticancer Polypharmacology

2022
Zhiguo Wang, Baofeng Yang
openaire   +1 more source

Hybrid Compounds in Polypharmacology

Current Topics in Medicinal Chemistry

Luciana Scotti, Marcus T. Scotti
openaire   +1 more source

Polypharmacology

2022
Zhiguo Wang, Baofeng Yang
openaire   +1 more source

Polypharmacology in Clinical Applications: Respiratory Polypharmacology

2022
Zhiguo Wang, Baofeng Yang
openaire   +1 more source

Polypharmacology in Clinical Applications: Renal Polypharmacology

2022
Zhiguo Wang, Baofeng Yang
openaire   +1 more source

Web-Based Tools for Polypharmacology Prediction

2018
Drug promiscuity or polypharmacology is the ability of small molecules to interact with multiple protein targets simultaneously. In drug discovery, understanding the polypharmacology of potential drug molecules is crucial to improve their efficacy and safety, and to discover the new therapeutic potentials of existing drugs.
Mahendra, Awale, Jean-Louis, Reymond
openaire   +2 more sources

Polypharmacology in Clinical Applications: Cardiovascular Polypharmacology

2022
Zhiguo Wang, Baofeng Yang
openaire   +1 more source

Polypharmacology in Clinical Applications: Metabolic Disease Polypharmacology

2022
Zhiguo Wang, Baofeng Yang
openaire   +1 more source