Results 211 to 220 of about 7,381 (220)

Polypharmacology in Drug Discovery

Clinical Pharmacology & Therapeutics, 2012
openaire   +2 more sources

Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets

Cell Chemical Biology, 2019
Claudia Ctortecka, Annamarie T Bryant, Bin Fang   +2 more
exaly  

Identification of Similar Binding Sites to Detect Distant Polypharmacology

Molecular Informatics, 2013
Xavier Jalencas, Jordi Mestres
exaly  

Exploiting polypharmacology for improving therapeutic outcome of kinase inhibitors (KIs): An update of recent medicinal chemistry efforts

European Journal of Medicinal Chemistry, 2018
Xiaoqing Lv, Xiaodong Ma
exaly  

In silico methods to address polypharmacology: current status, applications and future perspectives

Drug Discovery Today, 2016
Antonio Lavecchia, Carmen Cerchia
exaly  

Privileged Structures and Polypharmacology within and between Protein Families

ACS Medicinal Chemistry Letters, 2018
Joshua Meyers, Nicola E A Chessum, Ngai Mok   +2 more
exaly  

Polypharmacology of Berberine Based on Multi-Target Binding Motifs

Frontiers in Pharmacology, 2018
Yuedan Wang
exaly  

Polypharmacology

openaire   +1 more source

Target identification and polypharmacology of nutraceuticals

2016
György Dormán, Beáta Flachner, István Hajdú, Csaba D. András   +3 more
openaire   +1 more source

Polypharmacology: Repurposing ceritinib.

Nature reviews. Drug discovery
openaire   +1 more source