Results 91 to 100 of about 74,680 (298)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Polypharmacy in primary care: A population-based retrospective cohort study of electronic health records.

PLoS ONE
BackgroundPolypharmacy, prescription of multiple medications to a patient, is a major challenge for health systems. There have been no peer-reviewed studies of polypharmacy prevalence and medication cost at a population level in England.AimsTo determine ...
Thomas Woodcock, Derryn Lovett, Gloria Ihenetu, Vesselin Novov, Thomas Beaney, Keivan Armani, Angela Quilley, Azeem Majeed, Paul Aylin   +8 more
doaj   +1 more source

Environmental impact of antidepressants: Is a new prescription framework possible?

British Journal of Clinical Pharmacology, EarlyView.
Aims Antidepressants such as venlafaxine and sertraline pose high risks to water ecosystems. As depressive disorders and other mental health conditions become increasingly prevalent worldwide, prescription and environmental presence of these pharmaceuticals continue to rise. This study explores the practical viability of a new framework for prescribing
Matilde Bianconi, Valentina Giunchi, Michael Thiede, Elisa Sangiorgi, Marco Menchetti, Elisabetta Poluzzi   +5 more
wiley   +1 more source

Polypharmacy: Misleading, but manageable

, 2008
Reamer L Bushardt1, Emily B Massey1, Temple W Simpson1, Jane C Ariail2, Kit N Simpson31Department of Clinical Services, 2Center for Academic Excellence, Medical University of South Carolina, Charleston, South Carolina, USA; 3Department of Health ...
Massey, Emily B., Reamer L Bushardt, Ariail, Jane C., Bushardt, Reamer L., Kit N Simpson, Temple W Simpson, Simpson, Temple W., Simpson, Kit N., Emily B Massey, Jane C Ariail   +9 more
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Current practice and guideline adherence in renal dose adjustment for patients with chronic kidney disease: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed, Ahmed Tehemar, Mohamed Gasimelseed, Ahmed Gharaibeh, Muhammad Abdul Hadi, Kazeem Yusuff, Amani Zidan, Ahmed Awaisu   +7 more
wiley   +1 more source

Long‐acting cabotegravir and rilpivirine in people with HIV receiving chronic anticoagulation: A real‐world case series

British Journal of Clinical Pharmacology, EarlyView.
Background Long‐acting intramuscular cabotegravir plus rilpivirine (LA‐CAB + RPV) is an effective maintenance antiretroviral regimen for virologically suppressed people with HIV. However, its use in individuals receiving chronic anticoagulation is limited by concerns regarding intramuscular bleeding risk, and real‐world data are scarce.
Montserrat Laguno, Berta Torres, Maria Martínez‐Rebollar, Paula Arreba, Octavi Roman, Roger LLobet, Leire Berrocal, Alberto Foncillas, Júlia Calvo, Abiu Sempere, Ivan Chivite, Elisa de Lazzari, Josep Mallolas, Ana González‐Cordón   +13 more
wiley   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

Polypharmacy and healthcare expenditures among older adults in the United States: a propensity score-matched study

BMC Geriatrics
Background Polypharmacy is associated with increased risk of adverse events and may increase healthcare expenditures. However, there is a lack of study using nationally representative data to assess additional healthcare costs associated with ...
Shaoxi Pan, Shanshan Li, Yin Shi, Qi Kang, Shaoxiang Jiang, Gordon G. Liu, Hongyan Wu, Beini Lyu   +7 more
doaj   +1 more source

Polypharmacy among the elderly

Journal of Mid-life Health, 2018
Older people are at risk for polypharmacy due to multiple chronic diseases. Considering the lack of information in this regard, the aim of this study was to investigate the state of polypharmacy among the elderly in the city of Amirkola in northern part of Iran.This descriptive/analytical cross-sectional study is a part of Amirkola Health and Aging ...
Seyed Reza Hosseini, Ali Zabihi, Seyedeh Roghayeh Jafarian Amiri, Ali Bijani   +3 more
openaire   +3 more sources

Polypharmacy in pediatric patients and opportunities for pharmacists' involvement

, 2015
Alexis E Horace, Fahamina Ahmed School of Pharmacy, College of Health and Pharmaceutical Sciences, University of Louisiana at Monroe, Monroe, LA, USA Abstract: Rates of chronic conditions among pediatrics have been steadily increasing and medications ...
Horace AE, Ahmed F
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