Results 91 to 100 of about 66,109 (299)

Environmental impact of antidepressants: Is a new prescription framework possible?

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Antidepressants such as venlafaxine and sertraline pose high risks to water ecosystems. As depressive disorders and other mental health conditions become increasingly prevalent worldwide, prescription and environmental presence of these pharmaceuticals continue to rise. This study explores the practical viability of a new framework for prescribing
Matilde Bianconi   +5 more
wiley   +1 more source

Polypharmacy or medication washout: an old tool revisited [PDF]

open access: yes, 2011
Daniel A Hoffman1, Mark Schiller2, James M Greenblatt3, Dan V Iosifescu41Neuro-Therapy Clinic Inc, Denver, CO; 2Mind Therapy Clinic, 2299 Post Street, Suite 104A, San Francisco, CA; 3Comprehensive Psychiatric Resources, Waltham, MA; 4Mood and Anxiety ...
Schiller M   +3 more
core  

Polypharmacy [PDF]

open access: yes
Polypharmacy and super-polypharmacy in the under 65s – a scoping review of characteristics, risk and deprescribing ...
Jalpesh Trivedi
core   +1 more source

Failure to Reach a Consensus in Polypharmacy Definition: An Obstacle to Measuring Risks and Impacts—Results of a Literature Review [PDF]

open access: yes, 2020
Najwa Taghy, 1 Linda Cambon, 2 Jean-Marie Cohen, 3 Claude Dussart 4 1Laboratory P2S (Health Systemic Process), University of Lyon, University Claude Bernard of Lyon 1, Lyon, EA4129, France; 2Research Chair in Prevention, University of Bordeaux, ISPED ...
Cohen JM, Taghy N, Dussart C, Cambon L
core  

Management of severe bone loss in patients at risk of medication‐related osteonecrosis of the jaw with microsurgery and guided bone regeneration: A case study

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Medication‐related osteonecrosis of the jaw (MRONJ) is a challenging complication associated with antiresorptive medications. Its exact pathophysiology remains unclear, but dental extractions and infections are known triggers, complicating prevention, and treatment.
Pedro Franco Ferreira   +3 more
wiley   +1 more source

Polypharmacy in older adults with human immunodeficiency virus infection compared with the general population [PDF]

open access: yes, 2016
Mercedes Gimeno-Gracia,1 María José Crusells-Canales,2 Francisco Javier Armesto-Gómez,3 Vicente Compaired-Turlán,4 María José Rabanaque-Hernández5 1Pharmacy Department, Lozano Blesa University Clinical ...
Crusells-Canales MJ   +4 more
core  

Medication Prescribing Patterns for Chronic Kidney Diseases: Analysis of Drug-Dose Adjustments, Polypharmacy, and Drug Interactions [PDF]

open access: yes
Background: Multiple drug prescriptions in chronic kidney disease (CKD) escalate metabolic buildup, nephrotoxicity, and end stage kidney disease progression.
Ikilas Moldaliyev   +9 more
core   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples   +10 more
wiley   +1 more source

Breaking Down Psychiatric Polypharmacy: From Evidence to Practice

open access: yesAnnals of Indian Psychiatry
Psychiatric polypharmacy, the use of multiple psychotropic medications, has significantly increased in recent decades. Prescriptions for three or more medications went from 5% in 1974 to 40% in 1995. The rates vary widely, from 13% to 90% globally. About
Ketaki Ladi   +5 more
doaj   +1 more source

Strengthening Pharmacovigilance Reporting for Withdrawal Reactions to Support Deprescribing

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pharmacovigilance plays a crucial role in post‐marketing surveillance of medicines and relies on the spontaneous reporting of adverse drug reactions (ADRs). Discontinuation of a drug can cause clinically relevant signs and symptoms, including withdrawal reactions; however, this subset of ADRs is not fully accommodated in current pharmacovigilance ...
Zakir Khan, Frank Moriarty
wiley   +1 more source

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