Results 131 to 140 of about 99,805 (324)

Polypharmacy in elective lumbar spinal surgery for degenerative conditions with 24-month follow-up

Scientific Reports
We sought to identify long-term associations of medical complications and healthcare utilization related to polypharmacy following spinal surgery for degenerative lumbar pathology.
Nicholas Dietz, Chitra Kumar, Aladine A. Elsamadicy, Martin F. Bjurström, Katrina Wong, Alysha Jamieson, Mayur Sharma, Dengzhi Wang, Beatrice Ugiliweneza, Doniel Drazin, Maxwell Boakye   +10 more
doaj   +1 more source

An observational cross-sectional study on the impact of polypharmacy on medication adherence in patients with type 2 diabetes mellitus.

Student's Journal of Health Research Africa
Background: Polypharmacy is increasingly prevalent among patients with Type 2 Diabetes Mellitus (T2DM) due to frequent comorbidities. While multiple medications may be clinically justified, their cumulative burden can impair adherence, ultimately ...
Dr. Gayathri Elango, Dr. Athira Muralidas, Dr. Prasheeta V Praviraj   +2 more
doaj   +1 more source

β3‐Adrenoceptor Agonists for Neurogenic Lower Urinary Tract Dysfunction: Evidence and Clinical Rationale for First‐Line Therapy

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To summarize current evidence on β3‐adrenoceptor agonists for managing neurogenic lower urinary tract dysfunction (NLUTD), focusing on their efficacy, safety, and clinical role in optimizing bladder storage and protecting upper tracts. Methods Evidence from randomized controlled trials, meta‐analyses, and observational studies in spinal ...
Sharon E. Fishberg, Rano Matta
wiley   +1 more source

Comprehensive Insights into Natural Bioactive Compounds: From Chemical Diversity and Mechanisms to Biotechnological Innovations and Applications

ChemistryOpen, EarlyView.
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali, Atif Ali Khan Khalil, Muhammad Saeed Akhtar, Adnan Amin, Wajid Zaman   +4 more
wiley   +1 more source

Medication prescription patterns in cancer rehabilitation physiatry outpatients: A multicenter retrospective study

PM&R, EarlyView.
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen, Nafis Eghrari, David Leong, Philip Chang, Jasmine Zheng, Amy Ng, Richard Wilson, Mary Vargo   +7 more
wiley   +1 more source

Comorbidities and polypharmacy among HIV-positive patients aged 50 years and over: a case–control study [PDF]

, 2019
José Antonio Mata-Marín, Moisés Hermilo Martínez-Osio, Carla Ileana Arroyo-Anduiza, María de los Ángeles Berrospe-Silva, Alberto Chaparro-Sánchez, Itzel Cruz-Grajales, Javier Enrique Cruz-Herrera, Luis Antonio Uribe-Noguéz, Jesús Gaytán-Martı́nez, Medardo Jerónimo-Morales   +9 more
openalex   +1 more source

Development of a Novel Frailty Trigger for Use at Triage in the Emergency Department

Academic Emergency Medicine, EarlyView.
ABSTRACT Background Emergency Department (ED) Triage identifies patients with urgent needs. Frailty is not routinely identified and older patients presenting atypically may be inappropriately triaged as low priority. The introduction of a frailty modifier at triage is recommended in international guidelines, but is not yet widely‐adopted.
Elizabeth Moloney, Mark R. O'Donovan, Dearbhla Burke, Anne Healy, Maria Larkin, Anne O'Keeffe, Rónán O'Caoimh   +6 more
wiley   +1 more source

Management of Agitation in Emergency Medical Services for Older Adults: A Qualitative Exploration

Academic Emergency Medicine, EarlyView.
ABSTRACT Introduction Emergency medical services (EMS) providers are often first responders to agitated older adults, providing critical clinical care and transport. However, significant knowledge gaps persist in our understanding of agitation management for older adults in the prehospital setting.
Fatima I. Shah, Grace Lew, Ryan Lee, Krista Reich, Kathryn Crowder, Stephanie VandenBerg, Margaret McGillivray, Ian E. Blanchard, Zahra Goodarzi   +8 more
wiley   +1 more source

Medication taking behaviour and hypertension: A review of the literature [PDF]

, 2009
Hypertension is a global illness and one that affects circa 20% of the population. Despite the effectiveness of treatment, adherence with medication is a key concern, particularly in the elderly.
Banning, M
core  

Predicting Cognitive Change During Treatment for Inpatient Depression: Secondary Analysis From a Randomized Controlled Trial

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Individuals hospitalized with depression are particularly impacted by cognitive impairment. Identifying variables that predict improvements in cognition across treatment may inform more targeted and effective treatment approaches. We conducted secondary analyses to investigate baseline predictors of objective cognitive change in a
Zoe A. Odering, Jennifer Jordan, Cameron J. Lacey, Christopher M. Frampton, Richard J. Porter, Katie M. Douglas   +5 more
wiley   +1 more source